Results 201 to 210 of about 1,044,066 (265)

Continuous Imaging of the Cardiac Cycle Metabolism With Hyperpolarized [1‐13C]Pyruvate

NMR in Biomedicine, Volume 39, Issue 11, November 2026.
We present a continuous hyperpolarized 13C MRI framework for phase‐resolved imaging of myocardial metabolism throughout the entire cardiac cycle. By combining spectral‐spatial bicarbonate excitation with frequency‐shifted reconstruction of residual pyruvate signal, both metabolites are obtained from a single acquisition.
Mohsen Redda, Nikolaj Bøgh, Esben Søvsø Szocska Hansen, Uffe Kjærgaard, Rolf F. Schulte, Christoffer Laustsen   +5 more
wiley   +1 more source

In Situ Water Stable Isotope Techniques—A Review of the Latest Developments and a Call for Harmonization

WIREs Water, Volume 13, Issue 6, November/December 2026.
In our work, we review the advantages and limitations of a range of methods developed to collect in situ and in a minimally destructive manner the water vapor from soils, from plant xylem, and from the ecosystem atmosphere for the online or laboratory isotope analysis (δ2H and δ18O).
Natalie Orlowski, Matthias Beyer, Zuosinan Chen, Adrian Dahlmann, Maren Dubbert, Benjamin Gralher, Suzanne Jacobs, Jiri Kocum, Miriam Kreher, Angelika Kübert, Kathrin Kühnhammer, Samuel Le Gall, Marco M. Lehmann, Ruth‐Kristina Magh, John Marshall, Katrin Meusburger, Daniele Penna, Stefan Seeger, Daniel Schulz, Ilja van Meerveld, Youri Rothfuss   +20 more
wiley   +1 more source

Fatigue Assessment of Welded Joints Subjected to Multiaxial Loading Conditions through the Effective Critical Plane Approach

Fatigue &Fracture of Engineering Materials &Structures, Volume 49, Issue 11, Page 5048-5064, November 2026.
ABSTRACT Reliable fatigue design of welded components under multiaxial loading demands local criteria able to capture both the stress gradient at the weld notches and the influence of a complex loading condition including non proportionality of the stress‐strain load history. The Effective Critical Plane (ECP) approach, based on a stress averaging over
A. Chiocca, F. Frendo
wiley   +1 more source

Serum Response Factor Cooperates With Progesterone Receptor to Regulate Oviductal Smooth Muscle Gene Expression During Preimplantation Embryo Transport

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Oviductal smooth muscle contractions are important for preimplantation embryo transport under the regulation of steroid hormone signaling. Deletion of serum response factor (Srf) in progesterone receptor (Pgr)‐expressing cells leads to differential expression of 1670 genes in the mouse oviduct, 306 of which are directly bound by SRF.
Peter F. Lais, Ryan M. Marquardt, San‐Pin Wu, John P. Lydon, Francesco J. DeMayo   +4 more
wiley   +1 more source

Establishment and Characterization of a Stable hERG Cell Line for High-Throughput Drug Cardiac Safety Screening. [PDF]

Int J Mol Sci
Lu H, Guo Q, Qiu Q, Hu J.
europepmc   +1 more source

Elimination of Spurious Modes in Reduced‐Order‐Modeling‐Based Topology Optimization of Geometrically Nonlinear Structures

International Journal for Numerical Methods in Engineering, Volume 127, Issue 20, 30 October 2026.
ABSTRACT In geometrically nonlinear topology optimization, elements with low pseudo‐densities, subjected to compression from neighboring stiffer regions, can lead to complications, such as “inside‐out” elements in 2D structures or spurious local buckling in shells and plates.
Lidan Zhang, Fred van Keulen
wiley   +1 more source

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.
The paper describes the serendipitous discovery of chemical manipulation allowing the activator‐to‐inhibitor switching in Kv7.2 channel modulators. The molecular determinants driving this switch have been rationalized by multidisciplinary investigation encompassing synthetic and analytical chemistry, in silico methods, cryo‐EM analysis ...
Tania Ciaglia, Giusy Carleo, Zhenni Yang, Francesca Di Matteo, Federica De Rosa, Gerardina Smaldone, Zhao‐Bing Gao, Marco D'Alì, Rita Turcio, Demin Ma, Veronica Di Sarno, Nannan Su, Salvatore Vincenzo Giofrè, Giacomo Pepe, Pietro Campiglia, Alessia Bertamino, Francesco Miceli, Jiangtao Guo, Nunzio Iraci, Carmine Ostacolo, Maurizio Taglialatela   +20 more
wiley   +2 more sources

Selective activation of tetrodotoxin-sensitive sodium channels by AaH-II drives arrhythmogenic late Na+ current in the heart. [PDF]

Europace
Millet H, Choteau-Bodor M, Stervinou T, Bibault F, Godin S, Belhumeur P, Dereli M, Hivonnait A, Erfanian M, Tessier A, Girardeau A, Lamirault G, Charpentier F, Croyal M, Gaborit N, Montnach J, De Waard M.   +16 more
europepmc   +1 more source

OntOMat: Toward Ontology‐Based Product and Process Design Engineering and Optimization Solutions Fueling Circular Value Chains

Advanced Engineering Materials, Volume 28, Issue 20, 21 October 2026.
The OntOMat ontology establishes a structured framework for polymer matrix fiber reinforced composite materials, integrating manufacturing processes, characterization methods, and multiscale design through the VDI/VDE 3682 formalized process description standard.
Nicolas Christ, Jörg Hohe, Martin Kördel, Michael Giese, Niklas Toffert, Christian Seidel, Olaf Rehme, Patrik Schneider, Oliver Focke, Elie Abi Aoun, Claas Falldorf, Beñat Gutierrez, Alexandra Kühn, Sven Torstrick-von der Lieth, Christoph Herden, Erik Johannsen, Jan‐Uwe R. Schmidt, Felix Winkelmann, Andreas Schott, Daniel Schott   +19 more
wiley   +1 more source

Managing mitral annular calcification-high-end robotic mitral valve repair for experienced surgeons. [PDF]

J Thorac Dis
Bonatti J, Kobayashi K.
europepmc   +1 more source