Results 81 to 90 of about 9,980 (152)

A Val292 substitution combined with an alanine duplication (ADUP) in the Ω loop of ADC β-lactamase confers reduced susceptibility to advanced β-lactam agents, including cefiderocol. [PDF]

mBio
Kawai A, McElheny CL, Shields RK, Arias CA, Paterson DL, Patel R, Bonomo RA, Fowler VG, van Duin D, Doi Y.   +9 more
europepmc   +1 more source

<i>In vitro</i> activity of the novel β-lactamase inhibitor nacubactam against a nationwide collection of carbapenem-resistant Enterobacterales in Japan. [PDF]

JAC Antimicrob Resist
Yanagihara K, Tateda K, Doi Y, Takahashi S, Ohge H, Itahashi K, Okade H, Mikamo H.   +7 more
europepmc   +1 more source

Comment on "evaluation of high dose post-dialytic versus daily beta-lactam dosing in hemodialysis patients using Monte Carlo simulation". [PDF]

Int J Clin Pharm
Aljumaa SA, Al Musawa M, El Lababidi R, Abidi E, Ghazi I, El Nekidy WS.   +5 more
europepmc   +1 more source

Likelihood of aggressive PK/PD target attainment of continuous-infusion beta-lactams during the first week of treatment of febrile neutropenia: findings from a 1-year prospective, monocentric study in onco-haematological patients. [PDF]

J Antimicrob Chemother
Cojutti PG, Toschi A, Pasquini Z, Paolini S, Maffini E, Bonifazi F, Zinzani PL, Giannella M, Viale P, Pea F.   +9 more
europepmc   +1 more source

Accurate and Sensitive UHPLC-Tandem Mass Spectrometry Sequential Methods for Therapeutic Drug Monitoring of Aztreonam/Avibactam in Human Plasma. [PDF]

Pharmaceutics
Trozzi I, Giorgi B, De Paola R, Gatti M, Pea F.   +4 more
europepmc   +1 more source

The <i>in vitro</i> activity of aztreonam-avibactam and cefiderocol against globally collected clinical metallo-β-lactamase- and/or serine-carbapenemase-positive Enterobacterales isolates and the utility of commonly used <i>in vitro</i> diagnostic kits. [PDF]

Microbiol Spectr
Estabrook M, Streit C, Townsend A, Stone G, Kamat S, Sahm D.   +5 more
europepmc   +1 more source

Genomic and molecular characterisation of a KPC-producing Klebsiella pneumoniae clinical isolate resistant to meropenem-vaborbactam, imipenem-relebactam, and ceftazidime-avibactam. [PDF]

BMC Genom Data
Wan Y, Wong JLC, Sanchez-Garrido J, Low WW, Turton JF, Morecchiato F, Baccani I, Dodgson K, Rossolini GM, Woodford N, Frankel G, Jauneikaite E, Meunier D, Hopkins KL.   +13 more
europepmc   +1 more source

Cefiderocol Heteroresistance in NDM-Producing Enterobacterales: A Complex Polymicrobial Infection Successfully Salvaged With Ceftazidime-Avibactam Plus Aztreonam. [PDF]

Am J Case Rep
Nuaimi M, Cirillo J, Usbosy S, Egan D, Kovacich A, Madruga M, Carlan SJ.   +6 more
europepmc   +1 more source

Impact of Susceptibility Testing Methodology on the Positioning of Cefiderocol and Aztreonam-Avibactam Against Metallo-β-Lactamase-Producing Gram-Negative Bacteria. [PDF]

Antibiotics (Basel)
Del Nogal-Labrador F, González-Blanco B, Sanz MI, Recio R, Brañas P, Muñoz-Gallego I, Viedma E, Villa J.   +7 more
europepmc   +1 more source

Intrapulmonary penetration of ceftolozane/tazobactam and ceftazidime/avibactam administered by continuous infusion in critically ill patients with nosocomial pneumonia: a randomized pharmacokinetic trial. [PDF]

Crit Care
Benítez-Cano A, Sancho-Araiz A, Carazo J, Ramos I, Sánchez-Font A, Chalela R, López-Palacio M, García-Prieto FF, Navarrete-Rouco ME, Juanes-Borrego AM, Gómez-Junyent J, Horcajada JP, Adalia R, Roberts J, Sorlí L, Luque S.   +15 more
europepmc   +1 more source