Results 91 to 100 of about 132,737 (315)
Native silica nanoparticles are powerful membrane disruptors [PDF]
, 2015 Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
core +1 more source
Advanced Science, EarlyView.Spatiotemporal Supra‐LYTAC formation near cancerous membrane via CAIX‐targeting is achieved. As a result of generation of Supra‐LYTAC, POI trafficking into lysosome is significantly implemented for targeted protein degradation. Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable ...
Dohyun Kim +6 more
wiley +1 more source
Modification of the loops in the ligand-binding site turns avidin into a steroid-binding protein
BMC Biotechnology, 2011 Background Engineered proteins, with non-immunoglobulin scaffolds, have become an important alternative to antibodies in many biotechnical and therapeutic applications.
Kulomaa Markku S +9 more
doaj +1 more source
Advanced Science, EarlyView.Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu +7 more
wiley +1 more source
Pericentromeric organization at the fusion point of mouse Robertsonian translocation chromosomes [PDF]
, 2001 In mammals, Robertsonian (Rb) translocation (the joining of two telo/acrocentric chromosomes at their centromere to form a metacentric) is the most effective process in chromosomal evolution leading to speciation; its occurrence also affects human health
Capanna, E. +5 more
core +3 more sources
Advanced Contactless Bioassembly Approaches: Leveraging Sound, Optical, and Magnetic Fields
Advanced NanoBiomed Research, EarlyView.This review explores innovative contactless bioassembly techniques driven by sound, light, and magnetic fields, which enable the precise organization of cells, biomaterials, and bioactive substances into complex 3D structures. These technologies, crucial for in vitro modeling and regenerative medicine, are examined in detail, highlighting their ...
Micaela Natta +4 more
wiley +1 more source
Journal of Nanobiotechnology, 2011 Background The quantification of surface groups attached to non-woven fibers is an important step in developing nanofiber biosensing detection technologies.
Magnone Joshua +4 more
doaj +1 more source
Disruption of HOX activity leads to cell death that can be enhanced by the interference of iron uptake in malignant B cells. [PDF]
, 2010 The HOX genes encode a family of transcription factors that are dysregulated in several malignancies and have been implicated in oncogenesis and cancer cell survival.
Daniels, TR +5 more
core +1 more source
Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
Advanced NanoBiomed Research, EarlyView.This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou +4 more
wiley +1 more source
BMC Genomics, 2005 Background A chicken egg contains several biotin-binding proteins (BBPs), whose complete DNA and amino acid sequences are not known. In order to identify and characterise these genes and proteins we studied chicken cDNAs and genes available in the NCBI ...
Nordlund Henri R +5 more
doaj +1 more source