Results 91 to 100 of about 81,092 (236)

The raphe nuclear organization and serotonergic system in the bat (Artibeus planirostris)

open access: yesJournal of Anatomy, EarlyView.
Schematic representation of the methodological workflow used to characterize the serotonergic (5‐HT) system in the bat Artibeus planirostris. Serotonin (5‐HT) immunohistochemistry was performed on brainstem sections to identify and map the distribution of serotonergic neurons within the raphe nuclei.
Mariana D. Leite   +9 more
wiley   +1 more source

Intermittent hypoxia increases lipid insulin resistance in healthy humans: A randomized crossover trial

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
This scheme illustrates the main results of the present study showing an increase in circulating free fatty acids (FFA) that are likely to be related to several mechanisms like decrease in FFA insulin sensitivity and increase in FFA production. Significant changes are labelled in white, and non‐significant or hypothesis are labelled in pale green ...
Anne Briançon‐Marjollet   +8 more
wiley   +1 more source

Metabolic Reprogramming and GM‐CSF Secretion in Areca Nut‐Activated Fibroblasts Drive Oral Precancer Progression

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Oral cancer, with a rising global incidence and poor prognosis, is associated with areca nut use in South and Southeast Asia. In this study, we addressed the effects of areca nut extract (ANE) on oral carcinogenesis by modulating fibroblast behavior in oral tissue.
Yen‐Yun Wang   +9 more
wiley   +1 more source

Self-Assembled (Aza)BODIPY Dyes for Biomedical in Vivo Imaging. [PDF]

open access: yesAngew Chem Int Ed Engl
This minireview classifies (aza)BODIPY dyes according to their molecular stacking modes and aggregate types (H‐, oblique‐, or J‐type) in aqueous media, correlating these features with their multimodal imaging performance. By linking molecular design, exciton coupling, and pathway‐dependent assembly, we provide a framework for engineering next ...
Albers A, Masthoff M, Fernández G.
europepmc   +2 more sources

Epidermal PAR2‐TRPV3‐IL‐33 Signaling Promotes Mast Cell Recruitment and Sensory Nerve‐Mast Cell Interactions in Atopic Dermatitis

open access: yes
Allergy, EarlyView.
Jiahui Zhao   +10 more
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford   +9 more
wiley   +1 more source

The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Hong Gao   +5 more
wiley   +1 more source

Adipocytes in Aortic Stenosis: Association With Clinical and Morphological Indices

open access: yesClinical Anatomy, Volume 39, Issue 3, Page 325-331, April 2026.
ABSTRACT Recently, great attention has been given to understanding the new pathogenetic mechanisms underlying aortic stenosis (AS). The study aims to understand the role of mature adipocytes in AS and their association with histologic, clinical, and echocardiographic data, an area previously overlooked in AS research.
Elena Zoico   +9 more
wiley   +1 more source

Characterisation of bacteria‐induced colitis and its modulation by probiotics in naked mole rats: a new mammalian model for acute inflammatory disease

open access: yesThe Journal of Pathology, Volume 268, Issue 4, Page 493-511, April 2026.
Abstract Enteropathogenic bacteria are a major cause of morbidity and mortality globally. While mouse models have been indispensable in advancing our understanding of infectious enteric diseases, key differences in intestinal microbiota and immunobiology between mice and humans underscore the need for alternative mammalian models that better ...
Daniel W. Hart   +14 more
wiley   +1 more source

Doppel as an early‐stage biomarker promoting EMT and dissemination in ovarian cancers

open access: yesInternational Journal of Cancer, Volume 158, Issue 6, Page 1755-1768, 15 March 2026.
What's new? Existing biomarkers for ovarian cancer (OC) lack the sensitivity and specificity needed to consistently distinguish the malignancy from non‐ovarian influences and other cancers. Here, the authors explored the ability of the prion‐like protein Doppel, normally found in the male testes, to detect OC.
Zulfikar Azam   +18 more
wiley   +1 more source

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