Results 191 to 200 of about 899,641 (334)

Association of Synovial Innate Immune Exhaustion With Worse Pain in Knee Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Uncontrolled pain remains a major clinical challenge in the management of knee osteoarthritis (OA), the most common disabling joint disease. Worse pain is associated with synovial innate immune cell infiltration (synovitis), but the role of innate immune‐regulatory cells in pain is unknown. Our objective was to identify synovial innate immune
Holly T. Philpott, Trevor B. Birmingham, Garth Blackler, J. Daniel Klapak, Alexander J. Knights, Easton C. Farrell, Benoit Fiset, Logan A. Walsh, J. Robert Giffin, Edward M. Vasarhelyi, Steven J. MacDonald, Brent A. Lanting, Tristan Maerz, C. Thomas Appleton, on behalf of the WOREO Knee Study Group   +14 more
wiley   +1 more source

Double gene mutations of LRSAM1 and REEP1 and a new REEP1 mutation site found in a patient with amyotrophic lateral sclerosis with subjective paresthesia: A case report

Ibrain, EarlyView., 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by selective degeneration of upper and lower motor neurons. Leucine‐rich repeats and sterility α mutations in motif 1 (LRSAM1) has been proven to be involved in the pathogenesis of ALS.
Ji‐Yao Qin, Zun‐Lin Zhou, Yuan‐Qing Zhou, Ya Chen, Xiao‐Yan Yang, Hai‐Qing Zhang, Zu‐Cai Xu   +6 more
wiley   +1 more source

Integrin-mediated electric axon guidance underlying optic nerve formation in the embryonic chick retina. [PDF]

Commun Biol, 2023
Yamashita M.
europepmc   +1 more source

Short-Range Guidance of Olfactory Bulb Axons Is Independent of Repulsive Factor Slit [PDF]

, 2001
Tatsumi Hirata, Hajime Fujisawa, Jane Y. Wu, Yi Rao   +3 more
openalex   +1 more source

Visual and auditory attention in individuals with DYRK1A and SCN2A disruptive variants

Autism Research, EarlyView.
Abstract This preliminary study sought to assess biomarkers of attention using electroencephalography (EEG) and eye tracking in two ultra‐rare monogenic populations associated with autism spectrum disorder (ASD). Relative to idiopathic ASD (n = 12) and neurotypical comparison (n = 49) groups, divergent attention profiles were observed for the monogenic
Caitlin M. Hudac, Kelsey Dommer, Monique Mahony, Trent D. DesChamps, Brianna Cairney, Rachel Earl, Evangeline C. Kurtz‐Nelson, Jessica Bradshaw, Raphael A. Bernier, Evan E. Eichler, Emily Neuhaus, Sara Jane Webb, Frederick Shic   +12 more
wiley   +1 more source

Efferocytosis is restricted by axon guidance molecule EphA4 via ERK/Stat6/MERTK signaling following brain injury. [PDF]

J Neuroinflammation, 2023
Soliman E, Leonard J, Basso EKG, Gershenson I, Ju J, Mills J, de Jager C, Kaloss AM, Elhassanny M, Pereira D, Chen M, Wang X, Theus MH.   +12 more
europepmc   +1 more source

Cell-contact-dependent signalling in axon growth and guidance: Eph receptor tyrosine kinases and receptor protein tyrosine phosphatase β

, 1998
Sacha J. Holland, Elior Peles, Tony Pawson, Joseph Schlessinger   +3 more
openalex   +1 more source

Target-Derived GFRα1 as an Attractive Guidance Signal for Developing Sensory and Sympathetic Axons via Activation of Cdk5 [PDF]

, 2002
Fernanda Ledda, Gustavo Paratcha, Carlos F. Ibáñez   +2 more
openalex   +1 more source

m6A‐mRNA Reader YTHDF2 Identified as a Potential Risk Gene in Autism With Disproportionate Megalencephaly

Autism Research, EarlyView.
ABSTRACT Among autistic individuals, a subphenotype of disproportionate megalencephaly (ASD‐DM) seen at three years of age is associated with co‐occurring intellectual disability and poorer prognoses later in life. However, many of the genes contributing to ASD‐DM have yet to be delineated. In this study, we identified additional ASD‐DM candidate genes
Sierra S. Nishizaki, Nicholas K. Haghani, Gabriana N. La, Natasha Ann F. Mariano, José M. Uribe‐Salazar, Gulhan Kaya, Melissa Regester, Derek Sayre Andrews, Christine Wu Nordahl, David G. Amaral, Megan Y. Dennis   +10 more
wiley   +1 more source

Axon Guidance Molecules in the Islets of Langerhans. [PDF]

Front Endocrinol (Lausanne), 2022
Waters BJ, Blum B.
europepmc   +1 more source