Results 211 to 220 of about 104,244 (349)

LncRNA THUMPD3‐AS1 Regulates Behavioral and Synaptic Structural Abnormalities in Schizophrenia via miR‐485‐5p and ARHGAP8

Advanced Science, EarlyView.
Schizophrenia (SCZ) is linked to synaptic structural deficits driven by dysregulated noncoding RNAs. Using the novel ceRNAxis pipeline, THUMPD3‐AS1/miR‐485‐5p/ARHGAP8 is identified as a key regulator of actin cytoskeletal remodeling through noncanonical RhoB/C‐ROCK2 signaling. Modulating this axis ameliorates SCZ‐like phenotypes in mice and aligns with
Xiaojuan Gong, Lingxi Chen, Xin Guo, Anna Jiang, Yayi He, Chunxia Yan, Liang Ma, Jiayang Gao, Jinyu Zhang, Bao Zhang   +9 more
wiley   +1 more source

Mex3a-dependent post-transcriptional silencing ensures olfactory receptor diversity and axon guidance specificity. [PDF]

Cell Rep
Duffié R, Shayya H, Escamilla Del Arenal M, Wang M, Kahiapo J, Ugurbil A, Keskin A, Clowney F, Bashkirova EV, Pourmorady AD, Schieren I, Avila HI, Berchowitz LE, Barriga FM, Batlle E, Jovanovic M, Lomvardas S.   +16 more
europepmc   +1 more source

Axon Guidance Molecules in the Islets of Langerhans. [PDF]

Front Endocrinol (Lausanne), 2022
Waters BJ, Blum B.
europepmc   +1 more source

Retinal Ganglion Cell Axons Recognize Specific Guidance Cues Present in the Deafferented Adult Rat Superior Colliculus [PDF]

, 1996
Mathias Bähr, Andrea Wizenmann
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

3D-printed plugs enhance cell usage efficiency for single-cell migration and neuron axon guidance assays. [PDF]

Cell Rep Methods
Cheng J, Rock EC, Rao M, Chen HC, Ma Y, Chang KC, Chen YC.   +6 more
europepmc   +1 more source

Integrin-mediated electric axon guidance underlying optic nerve formation in the embryonic chick retina. [PDF]

Commun Biol, 2023
Yamashita M.
europepmc   +1 more source

Axon Guidance Molecules Guiding Neuroinflammation

, 2019
Won Suk Lee, Won‐Ha Lee, Yong Chul Bae, Kyoungho Suk   +3 more
openalex   +2 more sources

Cofilin 1 activation prevents the defects in axon elongation and guidance induced by extracellular alpha-synuclein [PDF]

, 2015
Sharada Tilve, Francesco Difato, Evelina Chieregatti   +2 more
openalex   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source