Results 111 to 120 of about 1,751 (156)
Some of the next articles are maybe not open access.
Structural biology of cytoplasmic and axonemal dyneins
Journal of Structural Biology, 2012Dyneins are microtubule-based, ATP-driven motor proteins with six tandemly linked AAA+ domains, a long N-terminal tail and a coiled-coil stalk. Cytoplasmic dyneins function as individual homodimers and are responsible for minus-end-oriented transport along microtubules. Axonemal dyneins of flagella/cilia are anchored in arrays to peripheral microtubule
openaire +2 more sources
Axonemal dynein expression in human fetal tracheal epithelium
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2002Ciliogenesis in human fetal airway epithelium occurs from 11 to 24 gestational weeks. Using genetic and antigenic markers specific for human axonemal dynein heavy chain 9, we characterized temporal aspects of axonemal dynein expression associated with large airway epithelial ciliogenesis during human fetal development.
Johnny L, Carson +6 more
openaire +2 more sources
Purification of Axonemal Dyneins and Dynein-Associated Components from Chlamydomonas
2009Axonemal dyneins are responsible for generating the force required to power ciliary and flagellar motility. These highly complex enzymes form the inner and outer arms associated with the outer doublet microtubules. They are built around one or more ~520kD heavy chains that exhibit motor activity and also include additional components that are required ...
openaire +2 more sources
Does axonemal dynein push, pull, or oscillate?
Cell Motility, 2003AbstractDynein is the molecular motor that provides motive force in cilia and flagella. Dynein is anchored to the A‐subtubule of the outer doublets by a club‐shaped extension called the stem, which supports the large globular head of the molecule. Dynein forms an attachment or cross‐bridge to the B‐subtubule of the adjacent outer doublet through a ...
Charles B, Lindemann, Alan J, Hunt
openaire +2 more sources
Cytoskeleton, 2014
The Ephemeroptera sperm axoneme is devoid of outer dynein arms (ODA) and exhibits a pronounced modification of the central pair complex (CPC), which is substituted by the central sheath (CS): a tubular element of unknown molecular composition. We performed a detailed ultrastructural analysis of sperm axonemes in the genera Cloeon and Ecdyonurus using ...
MENCARELLI, CATERINA +3 more
openaire +4 more sources
The Ephemeroptera sperm axoneme is devoid of outer dynein arms (ODA) and exhibits a pronounced modification of the central pair complex (CPC), which is substituted by the central sheath (CS): a tubular element of unknown molecular composition. We performed a detailed ultrastructural analysis of sperm axonemes in the genera Cloeon and Ecdyonurus using ...
MENCARELLI, CATERINA +3 more
openaire +4 more sources
Biochemical and Physiological Analysis of Axonemal Dyneins
2013Axonemal dyneins are highly complex molecular motors that power the beating of cilia/flagella. In addition to the motor subunits, these enzymes contain components that allow for assembly at the correct axonemal location and also enable the motor to respond to a broad array of signals including phosphorylation, Ca(2+), redox changes, and mechanical ...
openaire +2 more sources
Isoform-specific phosphorylation of axonemal dynein heavy chains
Molecular Biology of the CellAxonemal dyneins power ciliary motility and phosphorylation of key intermediate and light chain components affects the regulation and properties of these motors in very distantly related organisms. It is also known that many axonemal dynein heavy chains are subject to this posttranslational modification although this has been little studied.
Miho Sakato-Antoku +4 more
openaire +2 more sources
Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
DynAPs and cytoplasmic assembly of axonemal dyneins
Journal of Cell ScienceABSTRACT Motile cilia are microtubule-based organelles that generate fluid flow through coordinated beating, a process powered by axonemal dynein motors. Dyneins are pre-assembled in the cytoplasm by a suite of proteins called dynein axonemal assembly factors (DNAAFs).
John B. Wallingford +3 more
openaire +1 more source