Results 31 to 40 of about 594 (157)
Synthesis of Azaphilone-Based Chemical Libraries [PDF]
ACS Combinatorial Science, 2012 The synthesis of azaphilone scaffolds that have been further diversified by cross coupling acylation and amine addition is reported. Methodology development also led to novel modifications including C5 acetoxylation and condensations producing isoquinolin-6(7H) structures. Overall, the library synthesis afforded three azaphilone sublibraries, including
Achard, Mathieu +2 more
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Fungal Pigments and Their Roles Associated with Human Health
Journal of Fungi, 2020 Fungi can produce myriad secondary metabolites, including pigments. Some of these pigments play a positive role in human welfare while others are detrimental.
Lan Lin, Jianping Xu
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A Novel Azaphilone Muyophilone A From the Endophytic Fungus Muyocopron laterale 0307-2
Frontiers in Chemistry, 2021 Two known azaphilone derivatives, 4,6-dimethylcurvulinic acid (1) and austdiol (2), and their novel heterotrimer, muyophilone A (3), were isolated and identified from an endophytic fungus, Muyocopron laterale 0307-2.
Chao Yuan +6 more
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Recent advances in the chemistry and biology of azaphilones
RSC Advances, 2020 Recent advances in the chemistry and biology of structurally diverse azaphilones from 2012 to 2019.
Chunmei Chen +6 more
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Application and stability of fungal pigments using jelly sweets as a food model system
International Journal of Food Science &Technology, Volume 58, Issue 12, Page 6761-6774, December 2023., 2023 A workflow depicting the stability study of fungal pigments in jelly‐sweet model system. Summary Natural pigments have seen an increase in usage over the past decades due to their acclaimed safety and active biological properties. This is in line with the shift in consumer market preferences requiring a source replacement for synthetic colourants ...
Tumisi Beiri Jeremiah Molelekoa +3 more
wiley +1 more source
Chemistry – A European Journal, 2020 AbstractThe diversity of azaphilones in stromatal extracts of the fungus Hypoxylon fragiforme was investigated and linked to their biosynthetic machineries by using bioinformatics. Nineteen azaphilone‐type compounds were isolated and characterized by NMR spectroscopy and mass spectrometry, and their absolute stereoconfigurations were assigned by using ...
Kevin Becker +5 more
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Medicinal Research Reviews, Volume 43, Issue 3, Page 614-682, May 2023., 2023 Abstract Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight cancer and overcome drug resistance in antitumor therapy. Understanding the molecular interactions and structural features of ferroptosis‐inducing compounds might ...
Solveigh C. Koeberle +3 more
wiley +1 more source
European Journal of Organic Chemistry, Volume 2021, Issue 36, Page 5094-5103, September 24, 2021., 2021 Rubiginosins Z‐W, novel azaphilone pigments from stromata of Hypoxylon rubiginosum and H. texense, were isolated. Extensive HRMS, NMR, and ECD analysis revealed their stereochemistry and yielded missing configurations of known congeners. Unlike the related H. fragiforme, H. rubiginosum and H.
Kevin Becker +3 more
wiley +1 more source
New Azaphilones from Nigrospora oryzae Co-Cultured with Beauveria bassiana
Molecules, 2018 In this study, the co-culture of Nigrospora oryzae and Beauveria bassiana, the endophytes in the seeds of Dendrobium officinale, were examined for metabolite diversity.
Zhuo-Xi Zhang +7 more
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Frontiers in Microbiology, 2022 Five new chloro-azaphilones, chaetofanixins A–E (1–5), and five known analogs (6–10) were isolated and identified from the hadal trench-derived fungus Chaetomium globosum YP-106.
Yaqin Fan +8 more
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