New Cytotoxic Azaphilones from Monascus purpureus-Fermented Rice (Red Yeast Rice)
Using a cell-based cytotoxicity assay three new cytotoxic azaphilones, including two stereoisomers and designated monapurones A-C (1-3), were isolated from the extract of Monascus purpureus-fermented rice (red yeast rice).
Jinjie Li
exaly +3 more sources
Minutellins E-I and daldinone L, new secondary metabolites from different species of the Hypoxylaceae (Xylariales, Ascomycota) [PDF]
Fungi of the family Hypoxylaceae (Xylariales, Ascomycota) are ubiquitously distributed and fulfil important ecological roles as saprobes, pathogens, and endophytes.
Christopher Lambert +7 more
doaj +2 more sources
Fungal Pigments: Carotenoids, Riboflavin, and Polyketides with Diverse Applications [PDF]
Natural pigments and colorants have seen a substantial increase in use over the last few decades due to their eco-friendly and safe properties. Currently, customer preferences for more natural products are driving the substitution of natural pigments for
Maria Afroz Toma +5 more
doaj +2 more sources
Proangiogenic Azaphilones from the Marine-Derived Fungus Neopestalotiopsis sp. HN-1-6 [PDF]
Developing novel, safe, and efficient proangiogenic drugs is an important approach for the prevention and treatment of cardiovascular diseases. In this study, 4 new compounds, including 3 azaphilones (1–3) and 1 dihydroisocoumarin (4), as well as 13 ...
Ting Feng +6 more
doaj +2 more sources
From Pigment Chemistry to Nanomaterials: Fungal Pigments as Reducing and Stabilizing Agents in Green Nanoparticle Synthesis [PDF]
Fungal pigments have gained attention as eco-friendly and versatile materials for green nanotechnology because of their varied chemical structures, inherent redox properties, and strong metal ion-binding capabilities. These pigments, such as polyketides,
Akshay Chavan +4 more
doaj +2 more sources
Muyocopronones A and B: azaphilones from the endophytic fungus Muyocopron laterale
Two new azaphilones, namely muyocopronones A (1) and B (2), were isolated from the cultures of an endophytic fungus Muyocopron laterale ECN279. Their structures were elucidated by extensive spectroscopic analysis.
Yoshiaki Kawamura +2 more
exaly +2 more sources
Chemical Profiling and In Vitro Cytotoxicity Assessment of Commercial Red Yeast Rice Ingredients [PDF]
Red yeast rice (RYR) food supplements are widely used for cholesterol management due to their monacolin content, particularly monacolin K (MK), which shares the same chemical structure as lovastatin, a compound associated with several side effects.
Paola Nezi +8 more
doaj +2 more sources
Isolation and Characterization of Antimicrobial Metabolites from the Sophora tonkinensis-Associated Fungus Penicillium sp. GDGJ-N37 [PDF]
Chemical investigation of Penicillium sp. GDGJ-N37, a Sophora tonkinensis-associated fungus, yielded two new azaphilone derivatives, N-isoamylsclerotiorinamine (1) and 7-methoxyl-N-isoamylsclerotiorinamine (2), and four known azaphilones (3–6), together ...
Lili Huang +9 more
doaj +2 more sources
Novel bioactive compounds from marine-derived endosymbiotic Penicillium fungi reported during 2020–2025 [PDF]
Marine-derived Penicillium fungus gained significant attention in recent years due to their potential as a valuable source of unique natural compounds with a wide range of chemical structures and bioactive capabilities.
Sarah A. Omran +3 more
doaj +2 more sources
New Azaphilones, Seco-Chaetomugilins A and D, Produced by a Marine-Fish-Derived Chaetomium globosum
Seco-chaetomugilins A and D were isolated from a strain of Chaetomium globosum that was originally isolated from the marine fish Mugil cephalus, and their absolute stereostructures were elucidated on the basis of spectroscopic analyses, including 1D and ...
Reiko Tanaka
exaly +3 more sources

