Results 21 to 30 of about 559 (115)

The Impact of the Culture Regime on the Metabolome and Anti-Phytopathogenic Activity of Marine Fungal Co-Cultures [PDF]

Marine Drugs
Co-cultivation, coupled with the OSMAC approach, is considered an efficient method for expanding microbial chemical diversity through the activation of cryptic biosynthetic gene clusters (BGCs).
Mohammed Zawad Reza, Ernest Oppong-Danquah, Deniz Tasdemir   +2 more
doaj   +2 more sources

Chemical Constituents of the Deep-Sea-Derived Fungus Talaromyces wortmannii and Their Ferroptosis Inhibitory Activity. [PDF]

Chem Biodivers
One new tyramine derivative (1) and 28 known compounds (2–29) were isolated from deep‐sea‐derived fungus Talaromyces wortmannii. Their structures were elucidated by NMR/MS and computational calculations. Compounds 2 and 6 potently inhibited ferroptosis with EC5₀ values of 4.52 and 13.73 µM.
Ma KX, Zou ZB, Wu QQ, Li LS, Pan YN, Yang XW.   +5 more
europepmc   +2 more sources

Dereplication, Annotation, and Characterization of 74 Potential Antimicrobial Metabolites from Penicillium Sclerotiorum Using t-SNE Molecular Networks

Metabolites, 2021
Microorganisms associated with termites are an original resource for identifying new chemical scaffolds or active metabolites. A molecular network was generated from a collection of strain extracts analyzed by liquid chromatography coupled to tandem high-
Téo Hebra, Nicolas Elie, Salomé Poyer, Elsa Van Elslande, David Touboul, Véronique Eparvier   +5 more
doaj   +1 more source

Natural pigments derived from plants and microorganisms: classification, biosynthesis, and applications. [PDF]

Plant Biotechnol J
Summary Pigments, as coloured secondary metabolites, endow the world with a rich palette of colours. They primarily originate from plants and microorganisms and play crucial roles in their survival and adaptation processes. In this article, we categorize pigments based on their chemical structure into flavonoids, carotenoids, pyrroles, quinones ...
Tang Q, Li Z, Chen N, Luo X, Zhao Q.
europepmc   +2 more sources

Azaphilones Pigments from the Fungus Penicillium hirayamae

Colorants, 2023
The use of fungal pigments as dyes is attractive for various industries. Fungal pigments arise a strong interest because they are suitable for large-scale industrial production and have none of the drawbacks of synthetic pigments.
Coralie Pavesi, Victor Flon, Grégory Genta-Jouve, Elodie Pramil, Alexandre Escargueil, Adeel Nasir, Tristan Montier, Xavier Franck, Soizic Prado   +8 more
doaj   +1 more source

Anti-Inflammatory Azaphilones from the Edible Alga-Derived Fungus Penicillium sclerotiorum

Marine Drugs, 2021
To discover the new medical entity from edible marine algae, our continuously natural product investigation focused on endophytes from marine macroalgae Grateloupia sp.
Hui-Chun Wang, Tzu-Yi Ke, Ya-Chen Ko, Jue-Jun Lin, Jui-Sheng Chang, Yuan-Bin Cheng   +5 more
doaj   +1 more source

Fungal Pigments and Their Roles Associated with Human Health

Journal of Fungi, 2020
Fungi can produce myriad secondary metabolites, including pigments. Some of these pigments play a positive role in human welfare while others are detrimental.
Lan Lin, Jianping Xu
doaj   +1 more source

A Novel Azaphilone Muyophilone A From the Endophytic Fungus Muyocopron laterale 0307-2

Frontiers in Chemistry, 2021
Two known azaphilone derivatives, 4,6-dimethylcurvulinic acid (1) and austdiol (2), and their novel heterotrimer, muyophilone A (3), were isolated and identified from an endophytic fungus, Muyocopron laterale 0307-2.
Chao Yuan, Yuhua Guo, Ke Wang, Zhunian Wang, Longfei Li, Huajie Zhu, Gang Li   +6 more
doaj   +1 more source

Application and stability of fungal pigments using jelly sweets as a food model system

International Journal of Food Science &Technology, Volume 58, Issue 12, Page 6761-6774, December 2023., 2023
A workflow depicting the stability study of fungal pigments in jelly‐sweet model system. Summary Natural pigments have seen an increase in usage over the past decades due to their acclaimed safety and active biological properties. This is in line with the shift in consumer market preferences requiring a source replacement for synthetic colourants ...
Tumisi Beiri Jeremiah Molelekoa, Laura Suzanne da Silva, Thierry Regnier, Wilma Augustyn   +3 more
wiley   +1 more source

Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling

Medicinal Research Reviews, Volume 43, Issue 3, Page 614-682, May 2023., 2023
Abstract Ferroptosis is an iron‐dependent cell death program that is characterized by excessive lipid peroxidation. Triggering ferroptosis has been proposed as a promising strategy to fight cancer and overcome drug resistance in antitumor therapy. Understanding the molecular interactions and structural features of ferroptosis‐inducing compounds might ...
Solveigh C. Koeberle, Anna P. Kipp, Hermann Stuppner, Andreas Koeberle   +3 more
wiley   +1 more source