Fungal Pigments: Carotenoids, Riboflavin, and Polyketides with Diverse Applications [PDF]
Journal of Fungi, 2023 Natural pigments and colorants have seen a substantial increase in use over the last few decades due to their eco-friendly and safe properties. Currently, customer preferences for more natural products are driving the substitution of natural pigments for
Maria Afroz Toma +5 more
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Minutellins E-I and daldinone L, new secondary metabolites from different species of the Hypoxylaceae (Xylariales, Ascomycota) [PDF]
MycologyFungi of the family Hypoxylaceae (Xylariales, Ascomycota) are ubiquitously distributed and fulfil important ecological roles as saprobes, pathogens, and endophytes.
Christopher Lambert +7 more
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From Pigment Chemistry to Nanomaterials: Fungal Pigments as Reducing and Stabilizing Agents in Green Nanoparticle Synthesis [PDF]
MicroorganismsFungal pigments have gained attention as eco-friendly and versatile materials for green nanotechnology because of their varied chemical structures, inherent redox properties, and strong metal ion-binding capabilities. These pigments, such as polyketides,
Akshay Chavan +4 more
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Azaphilones from the Marine Sponge-Derived Fungus Penicillium sclerotiorum OUCMDZ-3839
Marine Drugs, 2019 Four new azaphilones, sclerotiorins A−D (1−4), as well as the dimeric sclerotiorin E (5) of which we first determined its absolute configuration, and 12 known analogues (5−16) were isolated from the fermentation broth of Penicillium ...
Qian Jia +5 more
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Isolation and Characterization of Antimicrobial Metabolites from the Sophora tonkinensis-Associated Fungus Penicillium sp. GDGJ-N37 [PDF]
MoleculesChemical investigation of Penicillium sp. GDGJ-N37, a Sophora tonkinensis-associated fungus, yielded two new azaphilone derivatives, N-isoamylsclerotiorinamine (1) and 7-methoxyl-N-isoamylsclerotiorinamine (2), and four known azaphilones (3–6), together ...
Lili Huang +9 more
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Novel bioactive compounds from marine-derived endosymbiotic Penicillium fungi reported during 2020–2025 [PDF]
Natural Products and BioprospectingMarine-derived Penicillium fungus gained significant attention in recent years due to their potential as a valuable source of unique natural compounds with a wide range of chemical structures and bioactive capabilities.
Sarah A. Omran +3 more
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Unique processes yielding pure azaphilones in Talaromyces atroroseus
Applied Microbiology and Biotechnology, 2019 Azaphilones are a class of fungal pigments, reported mostly in association with Monascus species. In Asian countries, they are used as food colourants under the name of "red yeast rice" and their production process is well described. One major limitation of current production techniques of azaphilones is that they always occur in a mixture of yellow ...
Gerit, Tolborg +4 more
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Generation of Novel Natural Products by Disrupting Azaphilone Synthesis in Penicillum sclerotiorum E23Y-1A [PDF]
Marine DrugsMarine-derived filamentous fungi are a rich source of structurally diverse and biologically active natural products. However, many biosynthetic gene clusters (BGCs) in fungi remain silent under standard conditions.
Wenjun Chang +5 more
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Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors
Bioorganic & Medicinal Chemistry, 2010 A series of mold metabolites of Ascomycetes, structurally belonging to the class of azaphilones, were found to inhibit the heat shock protein Hsp90. In particular, bulgarialactone B was tested for its binding to Hsp90 using surface plasmon resonance and limited proteolysis assays and for its effects on Hsp90 client proteins expression in a series of ...
Loana, Musso +17 more
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The Impact of the Culture Regime on the Metabolome and Anti-Phytopathogenic Activity of Marine Fungal Co-Cultures [PDF]
Marine DrugsCo-cultivation, coupled with the OSMAC approach, is considered an efficient method for expanding microbial chemical diversity through the activation of cryptic biosynthetic gene clusters (BGCs).
Mohammed Zawad Reza +2 more
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