Results 121 to 130 of about 29,405 (265)

An eco-compatible strategy for the diversity-oriented synthesis of macrocycles exploiting carbohydrate-derived building blocks

open access: yesBeilstein Journal of Organic Chemistry, 2017
An efficient, eco-compatible diversity-oriented synthesis (DOS) approach for the generation of library of sugar embedded macrocyclic compounds with various ring size containing 1,2,3-triazole has been developed.
Sushil K. Maurya, Rohit Rana
doaj   +1 more source

Chemoenzymatic tandem cyclization for the facile synthesis of bicyclic peptides

open access: yesCommunications Chemistry
Bicyclic peptides exhibit improved metabolic stabilities and target specificities when compared to their linear or mono-cyclic counterparts; however, efficient and straightforward synthesis remains challenging due to their intricate architectures.
Masakazu Kobayashi   +3 more
doaj   +1 more source

The Copper-Catalyzed Azide-Alkyne Cycloaddition Reaction: Why Two Is Faster than One. [PDF]

open access: yesChemphyschem
Quantum chemical analyses uncover that the copper‐catalyzed azide–alkyne cycloaddition favors the dinuclear catalyst mechanism over the mononuclear analog due to reduced steric Pauli repulsion between the copper acetylide and the azide, rather than relief of strain in the six‐membered metallacycle. The copper‐catalyzed azide–alkyne cycloaddition (CuAAC)
Vermeeren P.
europepmc   +2 more sources

Synthesis and antibacterial activity of new 1,2,3-triazolylmethyl-2H-1,4-benzothiazin-3(4H)-one derivatives

open access: yesChemistry Central Journal, 2018
Background A novel series of 1,2,3-triazole derivatives containing 1,4-benzothiazin-3-one ring (7a–9a, 7b–9b), (10a–12a, 10b–12b) and (13–15) were synthesized by 1,3-dipolar cycloaddition reactions of azides α-d-galactopyranoside azide F, 2,3,4,6-tetra-O-
Mohamed Ellouz   +8 more
doaj   +1 more source

Hierarchical single-crystal-to-single-crystal transformations of a monomer to a 1D-polymer and then to a 2D-polymer

open access: yesNature Communications
Designing and synthesizing flawless two-dimensional polymers (2D-Ps) via meticulous molecular preorganization presents an intriguing yet challenging frontier in research.
Haripriya Balan, Kana M. Sureshan
doaj   +1 more source

CuAAC-Based Assembly and Characterization of a New Molecular Dyad for Single Material Organic Solar Cell

open access: yesMetals, 2019
The synthesis and characterization of a new molecular dyad consisting of a benzodithiophene-based push-pull linked to a fullerene derivative through the use of the well-known Copper Azide-Alkyne Huisgen Cycloaddition (CuAAC) reaction is reported herein ...
Antoine Labrunie   +8 more
doaj   +1 more source

1-(2-Chlorobenzyloxy)-3-[1,2,3]triazol-1-yl-propan-2-ol Derivatives: Synthesis, Characterization, and DFT-Based Descriptors Analysis

open access: yesJournal of Chemistry, 2017
A novel series of 1-(2-chlorobenzyloxy)-3-[1,2,3]triazol-1-yl-propan-2-ol derivatives was designed and synthesized using copper catalyzed alkyne-azide cycloaddition in the key step.
Eloisa Román-Maldonado   +4 more
doaj   +1 more source

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