Results 21 to 30 of about 12,670 (211)

Luminescent Lariat Aza-Crown Ether

Molbank, 2010
Lariat ethers are interesting recognition motifs in supramolecular chemistry. The synthesis of a luminescent lariat ether with triglycol chain by azide–alkyne (Huisgen) cycloaddition is presented.
Burkhard König, Eva-Maria Rummel, Andreas Späth   +2 more
doaj   +1 more source

Dinuclear Copper(I) Thiodiacetate Complex-Mediated Expeditious Synthesis of the Chlorine-Containing Cyclen-Cored 36-Glucose-Coated Glycodendrimer

Journal of Chemistry, 2021
High-sugar-tethered glycodendrimers are a remarkable tool in glycobiology for the investigation of carbohydrate-protein interaction using its multivalency property.
Anand K. Agrahari, Sunil Kumar, Anindra Sharma, Vinod K. Tiwari   +3 more
doaj   +1 more source

A Genetically Encoded Picolyl Azide for Improved Live Cell Copper Click Labeling

Frontiers in Chemistry, 2021
Bioorthogonal chemistry allows rapid and highly selective reactivity in biological environments. The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is a classic bioorthogonal reaction routinely used to modify azides or alkynes that have been ...
Birthe Meineke, Birthe Meineke, Johannes Heimgärtner, Johannes Heimgärtner, Alexander J. Craig, Michael Landreh, Lindon W. K. Moodie, Lindon W. K. Moodie, Simon J. Elsässer, Simon J. Elsässer   +9 more
doaj   +1 more source

Luminescent Lariat Aza-Crown Ether Carboxylic Acid

Molbank, 2010
Lariat ethers are interesting recognition motifs in supramolecular chemistry. The synthesis of a luminescent lariat aza-crown ether with a carboxyl group appended by azide-alkyne (Huisgen) cycloaddition is presented.
Burkhard König, Eva-Maria Rummel, Andreas Späth   +2 more
doaj   +1 more source

Peptoids and polyamines going sweet: Modular synthesis of glycosylated peptoids and polyamines using click chemistry

Beilstein Journal of Organic Chemistry, 2013
Sugar moieties are present in a wide range of bioactive molecules. Thus, having versatile and fast methods for the decoration of biomimetic molecules with sugars is of fundamental importance.
Daniel Fürniss, Timo Mack, Frank Hahn, Sidonie B. L. Vollrath, Katarzyna Koroniak, Ute Schepers, Stefan Bräse   +6 more
doaj   +1 more source

Covalent Attachment of Aggregation-Induced Emission Molecules to the Surface of Ultrasmall Gold Nanoparticles to Enhance Cell Penetration

Molecules, 2022
Three different alkyne-terminated aggregation-induced emission molecules based on a para-substituted di-thioether were attached to the surface of ultrasmall gold nanoparticles (2 nm) by copper-catalyzed azide–alkyne cycloaddition (click chemistry).
Kai Klein, Matthias Hayduk, Sebastian Kollenda, Marco Schmiedtchen, Jens Voskuhl, Matthias Epple   +5 more
doaj   +1 more source

Site-Specific Fluorogenic Protein Labelling Agent for Bioconjugation

Biomolecules, 2020
Many clinically relevant therapeutic agents are formed from the conjugation of small molecules to biomolecules through conjugating linkers. In this study, two novel conjugating linkers were prepared, comprising a central coumarin core, functionalized ...
Kelvin K. Tsao, Ann C. Lee, Karl É. Racine, Jeffrey W. Keillor   +3 more
doaj   +1 more source

N-[7-Chloro-4-[4-(phenoxymethyl)-1H-1,2,3-triazol-1-yl]quinoline]-acetamide

Molbank, 2021
The 1,2,3-triazole is a well-known biologically active pharmacophore constructed by the copper-catalyzed azide–alkyne cycloaddition. We herein reported the synthesis of 4-amino-7-chloro-based [1,2,3]-triazole hybrids via Cu(I)-catalyzed Huisgen 1,3 ...
Paolo Coghi, Jerome P. L. Ng, Ali Adnan Nasim, Vincent Kam Wai Wong   +3 more
doaj   +1 more source

Microwave-assisted three-component domino reaction: Synthesis of indolodiazepinotriazoles

Beilstein Journal of Organic Chemistry, 2013
A microwave-assisted three-component protocol involving N-1 alkylation of 2-alkynylindoles with epichlorohydrin, ring opening of the epoxide with sodium azide, and an intramolecular Huisgen azide–internal alkyne 1,3-dipolar cycloaddition domino sequence ...
Rajesh K. Arigela, Sudhir K. Sharma, Brijesh Kumar, Bijoy Kundu   +3 more
doaj   +1 more source

Clickable azide-functionalized bromoarylaldehydes – synthesis and photophysical characterization

Beilstein Journal of Organic Chemistry, 2020
Herein, we present a facile synthesis of three azide-functionalized fluorophores and their covalent attachment as triazoles in Huisgen-type cycloadditions with model alkynes.
Dominik Göbel, Marius Friedrich, Enno Lork, Boris J. Nachtsheim   +3 more
doaj   +1 more source