Results 91 to 100 of about 18,930 (288)

Metal-free double azide addition to strained alkynes of an octadehydrodibenzo[12]annulene derivative with electron-withdrawing substituents

Beilstein Journal of Organic Chemistry
Strain-promoted azide–alkyne cycloaddition (SpAAC) is a powerful tool in the field of bioconjugation and materials research. We previously reported a regioselective double addition of organic azides to octadehydrodibenzo[12]annulene derivatives with ...
Naoki Takeda, Shuichi Akasaka, Susumu Kawauchi, Tsuyoshi Michinobu   +3 more
doaj   +1 more source

Synthesis and Characterization of Binary Azides (e.g. RbN3) via Ion-Exchange Method

Journal of the Turkish Chemical Society, Section A: Chemistry
Azides have garnered significant interest in chemical research for their diverse properties and applications, ranging from their use in airbags and detonators to their roles in photochemistry.
Semih Afyon
doaj   +1 more source

Screen-printed Microsensors Using Polyoctyl-thiophene (POT) Conducting Polymer As Solid Transducer for Ultratrace Determination of Azides

Molecules, 2019
Two novel all-solid-state potentiometric sensors for the determination of azide ion are prepared and described here for the first time. The sensors are based on the use of iron II-phthalocyanine (Fe-PC) neutral carrier complex and nitron-azide ion-pair ...
Ahmed Galal Eldin, Abd El-Galil E. Amr, Ayman H. Kamel, Saad S. M. Hassan   +3 more
doaj   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source

Dual Nickel/Photoredox‐Catalyzed Regio‐ and Enantioselective Alkenylation of Epoxides

Advanced Science, EarlyView.
Ni/photoredox‐catalyzed stereoconvergent cross‐electrophile coupling of racemic epoxides with alkenyl bromides is described, affording β‐alkenyl products with up to 95% ee, excellent E‐selectivity, and complete regiocontrol. These versatile intermediates enable diverse chiral synthons; mechanistic studies suggest a halide ring‐opening followed by ...
Hongyan Lan, Shengzhou Jin, Zhao‐Dong Xu, Guigen Li, Dingyi Wang   +4 more
wiley   +1 more source

Iron Corrole‐Catalyzed Intramolecular Amination Reactions of Alkyl Azides. Spectroscopic Characterization and Reactivity of [FeV(Cor)(NAd)]

Advanced Science
As nitrogen analogues of iron‐oxo species, high‐valent iron‐imido species have attracted great interest in the past decades. FeV‐alkylimido species are generally considered to be key reaction intermediates in Fe(III)‐catalyzed C(sp3)─H bond aminations of
Tingjie You, Ka‐Pan Shing, Liangliang Wu, Kai Wu, Hua‐Hua Wang, Yungen Liu, Lili Du, Runhui Liang, David Lee Phillips, Xiao‐Yong Chang, Jie‐Sheng Huang, Chi‐Ming Che   +11 more
doaj   +1 more source

New possibilities for the synthesis of reactive functional aminopolysilanes using azide pathway [PDF]

Memoirs of the Scientific Sections of the Romanian Academy, 2014
Two new reaction frameworks with high stereospecificity and high yields are described. Azidopolysilanes offers multiple options for obtaining aminopolysilanes, either by reducing the azido group using the Staudinger technique or by Huisgen 1,3 ...
Andrei Dascalu, Rodinel Ardeleanu, Bogdan C. Simionescu   +2 more
doaj  

α-Substituted vinyl azides: An emerging functionalized alkene [PDF]

, 2017
Vinyl azides are highly versatile synthons that provide access to numerous N-heterocycles and other functional groups. a-Substituted vinyl azides (azido vinylidenes) are a special class that display unique reactivity, able to react not only as azides ...
Xihe Bi, Fu, Junkai, Zanoni, Giuseppe, Junkai Fu, Bi, Xihe, Edward A. Anderson, Anderson, Edward A., Giuseppe Zanoni   +7 more
core   +1 more source

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source

Synthesis and applications of β-aminoethanesulfonyl azides

, 2006
A very efficient method for the synthesis of β-amino­ethanesulfonyl azides is descibed. These aliphatic sulfonyl azides are accessible starting from a variety of protected amino acids, including those having functionalized side chains. Furthermore, these
Rijkers, Dirk T.S., Remco Merkx, Afd Chemical Biology and Drug Discovery, Arwin J. Brouwer, Rijkers, D.T., Dabrowska, Katarzyna, Dirk T. S. Rijkers, Liskamp, R.M.J., Merkx, Remco, Merkx, R., Dabrowska, K., Medicinal Chemistry, Brouwer, A.J., Rob M. J. Liskamp, Brouwer, Arwin J., Katarzyna Dabrowska, Liskamp, Rob M.J.   +16 more
core   +1 more source