Results 241 to 250 of about 43,569 (363)

LC‐MS and High‐Throughput Data Processing Solutions for Lipid Metabolic Tracing Using Bioorthogonal Click Chemistry

open access: yesAngewandte Chemie, EarlyView.
This study introduces an integrated analytical and bioinformatics platform for high‐throughput tracing of lipid metabolism using bioorthogonal alkyne fatty acids and optimized LC‐MS workflow. Applied to human fibrosarcoma cells, the method traced fatty acid metabolism, revealing nuances in sphingolipid routing and metabolic bottlenecks, highlighting ...
Palina Nepachalovich   +7 more
wiley   +1 more source

Synthesis of enantiomerically enriched β-substituted analogs of (S)-α-alanine containing 1-phenyl-1H-1,2,3-triazole groups. [PDF]

open access: yesAmino Acids
Poghosyan AS   +8 more
europepmc   +1 more source

Studies in Azides. Part II. Synthesis of Some Substituted 1,2,3-Triazoles [PDF]

open access: green, 1963
Daleep Singh Deorha   +2 more
openalex   +1 more source

Supramolecular Gels as Active Tools for Reaction Engineering

open access: yesAngewandte Chemie, EarlyView.
The unique combination of environments within gels, self‐assembled from low‐molecular‐weight gelators, offers the ability to control reactivity in new ways, achieving unique reaction outcomes, leading to the emerging concept of supramolecular gels as nanoreactors. Smart chemical engineering methods enable the use of such gels to fabricate materials and
David K. Smith
wiley   +1 more source

New Developments in the Organic Chemistry of Fullerenes [PDF]

open access: yes, 1997
Bellavia-Lund, C.   +5 more
core   +2 more sources

Conditional Activation of Protein Therapeutics by Templated Removal of Peptide Nucleic Acid Masking Groups

open access: yesAngewandte Chemie, EarlyView.
A strategy for the conditional activation of therapeutic proteins utilizing removable peptide nucleic acid (PNA) masking groups is presented. Site‐specific installation of “Lock”‐PNAs containing a cleavage thioester linkage enabled steric blockage of receptor binding sites.
Bengt H. Gless   +6 more
wiley   +1 more source

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