Results 21 to 30 of about 73,246 (246)

Cobalt‐Porphyrin‐Catalysed Intramolecular Ring‐Closing C−H Amination of Aliphatic Azides: A Nitrene‐Radical Approach to Saturated Heterocycles

Chemistry, 2017
Cobalt‐porphyrin‐catalysed intramolecular ring‐closing C−H bond amination enables direct synthesis of various N‐heterocycles from aliphatic azides. Pyrrolidines, oxazolidines, imidazolidines, isoindolines and tetrahydroisoquinoline can be obtained in ...
P. F. Kuijpers, M. Tiekink, Willem B. Breukelaar, D. Broere, N. P. van Leest, J. I. van der Vlugt, J. Reek, B. de Bruin   +7 more
semanticscholar   +1 more source

Synthesis and Properties of 6-Aryl-4-azidocinnolines and 6-Aryl-4-(1,2,3-1H-triazol-1-yl)cinnolines

Molecules, 2019
An efficient approach towards the synthesis of 6-aryl-4-azidocinnolines was developed with the aim of exploring the photophysical properties of 6-aryl-4-azidocinnolines and their click reaction products with alkynes, 6-aryl-4-(1,2,3-1H-triazol-1-yl ...
Natalia A. Danilkina, Nina S. Bukhtiiarova, Anastasia I. Govdi, Anna A. Vasileva, Andrey M. Rumyantsev, Artemii A. Volkov, Nikita I. Sharaev, Alexey V. Povolotskiy, Irina A. Boyarskaya, Ilya V. Kornyakov, Polina V. Tokareva, Irina A. Balova   +11 more
doaj   +1 more source

Regioselective One-Pot Synthesis, Biological Activity and Molecular Docking Studies of Novel Conjugates N-(p-Aryltriazolyl)-1,5-benzodiazepin-2-ones as Potent Antibacterial and Antifungal Agents

Molecules, 2022
Novel 1,2,3-triazolo-linked-1,5-benzodiazepinones were designed and synthesized via a Cu(I)-catalyzed 1,3-dipolar alkyne-azide coupling reaction (CuAAC).
Asma Nsira, Hasan Mtiraoui, Sami Chniti, Hanan Al-Ghulikah, Rafik Gharbi, Moncef Msaddek   +5 more
doaj   +1 more source

Thiophene-2-carbonyl azide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2013
The title compound, C5H3N3OS, is almost planar (r.m.s. deviation for the ten non-H atoms = 0.018 Å) and forms an extended layer structure in the (100) plane, held together via hydrogen-bonding inter-actions between adjacent mol-ecules. Of particular note is the occurrence of RC-H⋯N(-)=N(+)=NR inter-actions between an aromatic C-H group and an azide ...
Michael Findlater, David B. Cordes, Laci M. Singer, Gene C. Hsu   +3 more
openaire   +3 more sources

Strain-Promoted 1,3-Dipolar Cycloaddition of Cycloalkynes and Organic Azides

Topics in current chemistry, 2016
A nearly forgotten reaction discovered more than 60 years ago—the cycloaddition of a cyclic alkyne and an organic azide, leading to an aromatic triazole—enjoys a remarkable popularity.
J. Dommerholt, F. Rutjes, F. V. van Delft   +2 more
semanticscholar   +1 more source

TMSBr-Promoted Cascade Cyclization of ortho-Propynol Phenyl Azides for the Synthesis of 4-Bromo Quinolines and Its Applications

Molecules, 2019
Difficult-to-access 4-bromo quinolines are constructed directly from easily prepared ortho-propynol phenyl azides using TMSBr as acid-promoter. The cascade transformation performs smoothly to generate desired products in moderate to excellent yields with
Fengyan Jin, Tao Yang, Xian-Rong Song, Jiang Bai, Ruchun Yang, Haixin Ding, Qiang Xiao   +6 more
doaj   +1 more source

Chemoselectivity of Tertiary Azides in Strain‐Promoted Alkyne‐Azide Cycloadditions

Chemistry, 2018
The strain‐promoted alkyne‐azide cycloaddition (SPAAC) is the most commonly employed bioorthogonal reaction with applications in a broad range of fields.
D. Svatunek, Nicole Houszka, Trevor A. Hamlin, F. Bickelhaupt, H. Mikula   +4 more
semanticscholar   +1 more source

Triazol-substituted titanocenes by strain-driven 1,3-dipolar cycloadditions

Beilstein Journal of Organic Chemistry, 2014
An operationally simple, convenient, and mild strategy for the synthesis of triazole-substituted titanocenes via strain-driven 1,3-dipolar cycloadditions between azide-functionalized titanocenes and cyclooctyne has been developed.
Andreas Gansäuer, Andreas Okkel, Lukas Schwach, Laura Wagner, Anja Selig, Aram Prokop   +5 more
doaj   +1 more source

Synthesis and Characterization of Azido- and Nitratoalkyl Nitropyrazoles as Potential Melt-Cast Explosives

Molecules, 2023
Desirable advancements in the field of explosive materials include the development of novel melt-castable compounds with melting points ranging from 80 to 110 °C.
Elena Reinhardt, Tobias Lenz, Lukas Bauer, Jörg Stierstorfer, Thomas M. Klapötke   +4 more
doaj   +1 more source

Solid-phase enrichment and analysis of electrophilic natural products

Beilstein Journal of Organic Chemistry, 2017
In search for new natural products, which may lead to the development of new drugs for all kind of applications, novel methods are needed. Here we describe the identification of electrophilic natural products in crude extracts via their reactivity ...
Frank Wesche, Yue He, Helge B. Bode
doaj   +1 more source