Results 71 to 80 of about 8,858 (221)
On Differences between Racemic and Enantiomerically Pure Forms of Aziridine-2-Carboxamide
Synthesis, X-ray and cytotoxicity studies of (S)- and (R)-aziridine-2-carboxamide (Leakadine) are described. X-Ray data of the enantiomerically pure form are compared with those for racemic aziridine-2-carboxamide in order to explain the 21 oC large ...
Meikas, A. +7 more
core +1 more source
A Study on the Biological Activity of Optically Pure Aziridine Phosphines and Phosphine Oxides
MoleculesA series of optically pure aziridine phosphines and their corresponding phosphine oxides were synthesized through established chemical methodologies. The compounds were systematically investigated for their biological properties. Notably, all synthesized
Aleksandra Kowalczyk +4 more
doaj +1 more source
Metal‐Catalyzed Transformations of Carbon Dioxide Toward the Production of Commodity Chemicals
Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.This perspective highlights how transition‐metal catalysis can enable the synthesis of economically attractive CO2‐derived commodity chemicals. By transforming waste CO2 into acrylic acid, cyclic carbonates, and other valuable products, these strategies provide a practical route for simultaneous CO2 sequestration and valorization, helping to align ...
Chaodi Dai +2 more
wiley +1 more source
Aziridine-Mediated Ligation and Site-Specific Modification of Unprotected Peptides
, 2016 A synthesis of aziridine-containing peptides via the Cu(II)-promoted coupling of unprotected peptide thioacids and N–H aziridine-2-carbonyl peptides is reported.
Ryan Joseph (1831123) +3 more
core +1 more source
Machine Learning for Synthetic Organic Chemistry: Methods, Applications, and Best Practices
Angewandte Chemie Novit, Volume 2, Issue 3, September 2026.Artificial intelligence (AI) and machine learning (ML) are increasingly reshaping experimental chemistry. This review maps the challenges of synthetic organic chemistry to modern digital tools that can help address them. While focusing on the practical application of ML tools in real‐world laboratory settings, we outline prerequisites, emerging ...
Niklas Hölter +3 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2011 A novel synthetic methodology has been developed for the synthesis of diethyl 5-alkyl/aryl/heteroaryl substituted 3,4-dihydro-2H-pyrrole-4,4-dicarboxylates (also called 2-substituted pyrroline-4,5-dihydro-3,3-dicarboxylic acid diethyl esters) by iodide ...
Satish S. More +4 more
doaj +1 more source
Aziridine Lithiation Using Lewis Acid Activation
, 2016 Aziridine Lithiation Using Lewis Acid ...
Edwin Vedejs (1264683) +1 more
core +1 more source
Methamphetamine Enantiomers: From Chemical Synthesis to Biological Fate
Chirality, Volume 38, Issue 9, September 2026.Methamphetamine is an amphetamine‐type stimulant characterized by a single stereogenic center, resulting in two enantiomers, (R)‐(−)‐methamphetamine and (S)‐(+)‐methamphetamine, with distinct biological and pharmacological profiles. These forms exhibit differences in central nervous system activity, metabolism, excretion, and overall physiological ...
Larissa Pires do Espírito Santo +9 more
wiley +1 more source
5-Azido-4-dimethylamino-1-methyl-1,2,4-triazolium Hexafluoridophosphate and Derivatives
Crystals, 2016 5-Azido-4-(dimethylamino)-1-methyl-1,2,4-triazolium hexafluoridophosphate was synthesized from the corresponding 5-bromo compound with NaN3. Reaction with bicyclo[2.2.1]hept-2-ene yielded a tricyclic aziridine, addition of an N-heterocyclic carbene ...
Gerhard Laus +2 more
doaj +1 more source
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
European Journal of Organic Chemistry, Volume 29, Issue 32, 24 August 2026.In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source