Advances in the Different Synthetic Routes of Fluorinated Hydrazines
This review highlights the various routes to the preparation of fluorinated hydrazines, thereby promoting the exploration of innovative methods for the synthesis of new N‐fluorinated hydrazines. Their synthesis mainly involves synthetic routes such as organometallic, organocatalytic, and photocatalytic.
Dimitra Kyrko, Benoît Crousse
wiley +1 more source
A Study on the Biological Activity of Optically Pure Aziridine Phosphines and Phosphine Oxides
A series of optically pure aziridine phosphines and their corresponding phosphine oxides were synthesized through established chemical methodologies. The compounds were systematically investigated for their biological properties. Notably, all synthesized
Aleksandra Kowalczyk +4 more
doaj +1 more source
Metal-free one-pot synthesis of 2-substituted and 2,3-disubstituted morpholines from aziridines
The metal-free synthesis of 2-substituted and 2,3-disubstituted morpholines through a one-pot strategy is described. A simple and inexpensive ammonium persulfate salt enables the reaction of aziridines with halogenated alcohols to proceed via an SN2-type
Hongnan Sun +4 more
doaj +1 more source
Síntese de azirinas contendo um grupo metileno ativado como precursores de heterociclos multifuncionalizados [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas, Programa de Pós-Graduação em Química, Florianópolis, 2015.Neste trabalho foi desenvolvida uma rota sintética simples e eficiente para a síntese de ...
Rossa, Thaís Andreia
core
Isotopic labelling studies for a gold-catalysed skeletal rearrangement of alkynyl aziridines
Isotopic labelling studies were performed to probe a proposed 1,2-aryl shift in the gold-catalysed cycloisomerisation of alkynyl aziridines into 2,4-disubstituted pyrroles.
Paul W. Davies +2 more
doaj +1 more source
Short and Efficient Synthesis of Optically Active N-Tosyl Aziridines from 2-Amino Alcohols
Two alternative and complementary one-pot procedures for the direct transformation of 2-amino alcohols to N-tosyl aziridines are presented. The unsubstituted parent compound and its less hindered homologues can be obtained in high yields by tosylation ...
Maria C. F. de Araújo +1 more
doaj +1 more source
Dimerization and isomerization reactions of alpha-lithiated terminal aziridines.
The scope of dimerization and isomerization reactions of alpha-lithiated terminal aziridines is detailed. Regio- and stereoselective deprotonation of simple terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide (LTMP) or lithium ...
Hodgson, DM +5 more
core +1 more source
Triazolylmethyl Aziridines with Various Side Chain
More than hundred compounds from aziridine class shown certain biological activity. We report here the synthesis of racemic version of protected azidomethyl aziridine via easily accessible intermediates.
Trapencieris, Pēteris +4 more
core
Heterogeneous polymer-supported triphenylphosphine oxides based on the rasta resin architecture have been synthesized, and applied as reagent precursors in a wide range of halogenation reactions.
Xuanshu Xia, Patrick H. Toy
doaj +1 more source
Hard to make space: improving access to privileged pharmacophores
Limited examples of the successful ring expansion of aziridines with sulfonium ylides to generate azetidines are known, but typically result in functional groups on azetidine that are not broadly useful for downstream chemistry.
Wilkinson, Christopher Trevor
core

