Results 71 to 80 of about 6,575 (208)
Development and application of the vinylepoxide – dihydrofuran rearrangement [PDF]
, 2000 The vinylepoxide - diliydrofuran rearrangement offers a route to substituted 2,3- dihydrofurans with a high degree of diastereoselectivity. The rearrangement proceeds via an ylide-type intermediate arising from the thermolysis of a carbon-carbon epoxide ...
Dutton, William Martin
core
Methamphetamine Enantiomers: From Chemical Synthesis to Biological Fate
Chirality, Volume 38, Issue 9, September 2026.Methamphetamine is an amphetamine‐type stimulant characterized by a single stereogenic center, resulting in two enantiomers, (R)‐(−)‐methamphetamine and (S)‐(+)‐methamphetamine, with distinct biological and pharmacological profiles. These forms exhibit differences in central nervous system activity, metabolism, excretion, and overall physiological ...
Larissa Pires do Espírito Santo +9 more
wiley +1 more source
Deprotection of sulfonyl aziridines
, 1998 The deprotection of the chiral N-sulfonyl aziridines 1-3 has been studied under different desulfonylation conditions. Two methods for the efficient deprotection of 2-benzyl-, 2-phenyl-, and 2-carboxyl-N-sulfonylaziridines were found.
Andersson, PG,, Alonso, DA,
core +5 more sources
Facile and Green Synthesis of Saturated Cyclic Amines
Molecules, 2017 Single-nitrogen containing saturated cyclic amines are an important part of both natural and synthetic bioactive compounds. A number of methodologies have been developed for the synthesis of aziridines, azetidines, pyrrolidines, piperidines, azepanes and
Arruje Hameed +7 more
doaj +1 more source
Synthesis and chemistry of methyleneaziridines bearing aryl groups [PDF]
This thesis describes the synthesis of methyleneaziridines bearing aryl groups and investigates some of their chemistry, focusing on thermal rearrangements and metal catalysed reactions.
Bayliffe, Frances
core
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
European Journal of Organic Chemistry, Volume 29, Issue 32, 24 August 2026.In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source
Chemistry – A European Journal, Volume 32, Issue 31, 18 August 2026.Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato +3 more
wiley +1 more source
Nature Communications, 2019 Due to their poor electrophilicity, 2H-azirines do not easily react with nucleophiles. Here, the authors show an acidic activation of 2H-azirines by cyanoacetic acid coupling partners affording chiral aziridines containing vicinal tetrasubstituted and ...
Hai-Jun Zhang, Yan-Cheng Xie, Liang Yin
doaj +1 more source
MoleculesThe asymmetric [3+2] cycloaddition of azomethine ylides generated from the corresponding imino ester-to-trans-β-nitrostyrene catalysis by chiral aziridine-containing phosphines and phosphine oxides is described. Of the sixteen stereoisomers that could be
Julia Szymańska +2 more
doaj +1 more source
Catalytic Asymmetric Synthesis of Trisubstituted Aziridines
, 2016 A method is described which provides for the direct asymmetric catalytic synthesis of trisubstituted aziridines from imines and diazo compounds. While unactivated imines were not reactive to α-diazo carbonyl compounds in which the diazo carbon was ...
William D. Wulff (1338240) +1 more
core +1 more source