Results 71 to 80 of about 5,649 (226)
Synthesis and chemistry of methyleneaziridines bearing aryl groups [PDF]
This thesis describes the synthesis of methyleneaziridines bearing aryl groups and investigates some of their chemistry, focusing on thermal rearrangements and metal catalysed reactions.
Bayliffe, Frances
core
European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer +6 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2010 N-Phosphonate terminal aziridines undergo lithium 2,2,6,6-tetramethylpiperidide-induced N- to C-[1,2]-anionic phosphonyl group migration under experimentally straightforward conditions, to provide a stereocontrolled access to synthetically valuable trans-
David. M. Hodgson, Zhaoqing Xu
doaj +1 more source
, 2023 The arylation of 2-alkyl aziridines by nucleophilic ring-opening or transition metal-catalyzed cross-coupling enables facile access to biologically relevant beta-phenethylamine derivatives. However, both approaches largely favor C–C bond formation at the
Abigail, Doyle +2 more
core +1 more source
European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.Glycomimetics with triazoline and aziridine groups were synthesised via diastereoselective Huisgen cycloaddition from glycosyl azides. Density functional theory was applied to define the mechanism for BF3 promoted aziridine formation. Triazoline and aziridine derivatives were synthesised by diastereo‐ and regioselective Huisgen cycloaddition of 2,3,4,6‐
Aaron McCormack +4 more
wiley +1 more source
Molecules, 2014 The coupling of proline- and azetidinone-substituted alkenes to 2-azidobenzoic and 2-azidobenzenesulfonic acid gives precursors that undergo intramolecular azide to alkene 1,3-dipolar cycloadditions to give imine-, triazoline- or aziridine-containing ...
Karl Hemming +3 more
doaj +1 more source
Catalytic Asymmetric Synthesis of Trisubstituted Aziridines
, 2016 A method is described which provides for the direct asymmetric catalytic synthesis of trisubstituted aziridines from imines and diazo compounds. While unactivated imines were not reactive to α-diazo carbonyl compounds in which the diazo carbon was ...
William D. Wulff (1338240) +1 more
core +1 more source
, 2022 Aziridines are readily available C(sp3) precursors that afford valuable β-functionalized amines upon ring-opening. In this article, we report a Ni/photoredox methodology for C(sp3)−C(sp3) cross-coupling between aziridines and me-thyl/1⁰/2⁰ aliphatic ...
Sun, Dongbang, Abigail, Doyle
core +1 more source
Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II
European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley +1 more source
Facile and Green Synthesis of Saturated Cyclic Amines
Molecules, 2017 Single-nitrogen containing saturated cyclic amines are an important part of both natural and synthetic bioactive compounds. A number of methodologies have been developed for the synthesis of aziridines, azetidines, pyrrolidines, piperidines, azepanes and
Arruje Hameed +7 more
doaj +1 more source