Results 11 to 20 of about 1,101 (192)

Synthesis and Application of Bioactive N-Functionalized Aziridines. [PDF]

Angew Chem Int Ed Engl
This review discusses modern synthetic methods for the preparation of aziridine‐containing small molecules, including biocatalytic, electrocatalytic, and photocatalytic strategies. We highlight the compatibility of various synthetic methods with control of the exocyclic N‐substituent.
Tan H, Samanta S, Qiu N, Adibekian A, Powers DC.   +4 more
europepmc   +3 more sources

3-Aryl-2H-azirines as annulation reagents in the Ni(II)-catalyzed synthesis of 1H-benzo[4,5]thieno[3,2-b]pyrroles [PDF]

Beilstein Journal of Organic Chemistry
A high-yielding method for the synthesis of 3-arylbenzo[4,5]thieno[3,2-b]pyrroles has been developed via pyrrole ring annulation to the aromatic benzo[b]thiophene system, using 3-arylazirines as a N‒C=C synthon.
Julia I. Pavlenko, Pavel A. Sakharov, Anastasiya V. Agafonova, Derenik A. Isadzhanyan, Alexander F. Khlebnikov, Mikhail S. Novikov   +5 more
doaj   +2 more sources

Azirinyl-Substituted Nitrile Oxides: Generation and Use in the Synthesis of Isoxazole Containing Heterocyclic Hybrids [PDF]

Molecules
The procedure for the generation of azirinyl-substituted nitrile oxides by the reaction of 2-(diazoacetyl)-2H-azirines with tert-butyl nitrite while preserving the azirine ring has been developed.
Alexander S. Dudik, Timur O. Zanakhov, Ekaterina E. Galenko, Mikhail S. Novikov, Alexander F. Khlebnikov   +4 more
doaj   +2 more sources

Diverse reactivity of maleimides in polymer science and beyond. [PDF]

Polym Int
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Kirkpatrick BE, Anseth KS, Hebner TS.
europepmc   +2 more sources

A sustainable strategy for the straightforward preparation of 2H-azirines and highly functionalized NH-aziridines from vinyl azides using a single solvent flow-batch approach [PDF]

Beilstein Journal of Organic Chemistry, 2021
The reported flow-batch approach enables the easy preparation of 2H-azirines and their stereoselective transformation into highly functionalized NH-aziridines, starting from vinyl azides and organolithium compounds.
Michael Andresini, Leonardo Degannaro, Renzo Luisi   +2 more
doaj   +2 more sources

Acridine–Isoxazole and Acridine–Azirine Hybrids: Synthesis, Photochemical Transformations in the UV/Visible Radiation Boundary Region, and Anticancer Activity [PDF]

Molecules
Easy-to-handle N-hydroxyacridinecarbimidoyl chloride hydrochlorides were synthesized as convenient nitrile oxide precursors in the preparation of 3-(acridin-9/2-yl)isoxazole derivatives via 1,3-dipolar cycloaddition with terminal alkynes, 1,1 ...
Ekaterina E. Galenko, Mikhail S. Novikov, Alexander S. Bunev, Alexander F. Khlebnikov   +3 more
doaj   +2 more sources

Isomerization of 5-(2H-Azirin-2-yl)oxazoles: An Atom-Economic Approach to 4H-Pyrrolo[2,3-d]oxazoles [PDF]

Molecules, 2021
An atom economical method for the preparation of variously substituted 4H-pyrrolo[2,3-d]oxazoles was developed on the basis of thermal isomerization of 5-(2H-azirin-2-yl)oxazoles.
Timur O. Zanakhov, Ekaterina E. Galenko, Mariya A. Kryukova, Mikhail S. Novikov, Alexander A. Khlebnikov   +4 more
doaj   +2 more sources

2H-Azirines as electrophiles [PDF]

, 2011
2H-Azirines have shown an unusual potential to synthesise aziridines and other types of compounds. Many functionalized aziridines can be produced by addition of O-, S-,N-, C-nucleophiles and hydride to 2H-azirines. This review is designed to give an overview of the reactivity of 2H-azirines as electrophiles along the years and their usefulness in the ...
Alves, M. José, Costa, Flora Teixeira e
openaire   +2 more sources

Cobalt catalyst with exclusive metal-centered chirality for asymmetric photocatalysis [PDF]

Nature Communications
For decades, progress in chiral transition metal catalysis has been closely linked to the design of tailor-made chiral ligands. Recently, an alternative to this conventional paradigm has emerged in which the overall chirality of the catalysts arises ...
Su-Yang Yao, Marco Villa, Yuan Zheng, Antonio Fiorentino, Barbara Ventura, Sergei I. Ivlev, Paola Ceroni, Eric Meggers   +7 more
doaj   +2 more sources

Diastereoselective ZnCl₂-Mediated Joullié–Ugi Three-Component Reaction for the Preparation of Phosphorylated N-Acylaziridines from 2H-Azirines [PDF]

Molecules
We disclose a direct approach to the diastereoselective synthesis of phosphorus substituted N-acylaziridines based on a one-pot ZnCl2-catalyzed Joullié–Ugi three-component reaction of phosphorylated 2H-azirines, carboxylic acids and isocyanides.
Julene Allende, Iurre Olaizola, Ana M. Ochoa de Retana, Francisco Palacios, Jesús M. de los Santos   +4 more
doaj   +2 more sources