Results 21 to 30 of about 1,276 (179)
Late-Stage Functionalization of Peptides on the Solid Phase. [PDF]
Angew Chem Int Ed EnglPeptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Werner M, Pham TL, Thomas F.
europepmc +2 more sources
A Chemical Framework for Engineering Extracellular Vesicles' Biointerface to Advance Precision Therapeutics. [PDF]
Adv MaterExtracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Pourtalebi Jahromi L +3 more
europepmc +2 more sources
SynOpen, 2022 An efficient organo-photocatalytic method for the synthesis of tetrasubstituted pyrroles bearing a ketone, ester, alcohol, or nitro group at the 3-position has been developed.
Lalita Devi +3 more
doaj +1 more source
Simple Conversion of Enamines to 2H-Azirines and Their Rearrangements under Thermal Conditions
, 2016 A variety of substituted enamine derivatives were first found to be conveniently converted to the corresponding 2H-azirines mediated by phenyliodine (III) diacetate (PIDA).
Yunfei Du (1490683) +5 more
core +3 more sources
[3 + 2]-Cycloadditions of nitrile ylides after photoactivation of vinyl azides under flow conditions
Beilstein Journal of Organic Chemistry, 2013 The photodenitrogenation of vinyl azides to 2H-azirines by using a photoflow reactor is reported and compared with thermal formation of 2H-azirines. Photochemically, the ring of the 2H-azirines was opened to yield the nitrile ylides, which underwent a [3
Stephan Cludius-Brandt +2 more
doaj +1 more source
Tetrahedron Letters, 1976 Tetrahedron Letters 17 (1976) 1413-1414. doi:10.1016/S0040-4039(00)71270-6 ; Received by publisher: 1975-12-23 ; Harvest Date: 2016-01-04 12:20:50 ; DOI:10.1016/S0040-4039(00)71270-6 ; Page Range: 1413 ...
Department of Chemistry, University of Florida Gainesville, Florida 32611 U.S.A. ( host institution ) +2 more
openaire +2 more sources
Synthesis of Stable 1H-Azirines Reinvestigated: A Structural Corrigendum [PDF]
, 2012 The isoquinoline-catalyzed synthesis of pretended 1H-azirines from phenacyl bromides and N,N\'-dialkylcarbodiimides was repeated. The products do not possess the structure of antiaromatic 1H-azirines, but simple N-acyl-N,N\'-dialkylureas were formed ...
Peisker, Heiko +2 more
core +1 more source
, 2016 The reaction of 3-azido-2,3-dideoxy-hexopyranose compounds from the d-gluco, d-galacto, d-lacto, and l-arabino carbohydrate series, with (diacetoxyiodo)benzene and iodine, generated 2-azido-1,2-dideoxy-1-iodo-alditols with one carbon less than the ...
María S. Rodríguez (3030198) +3 more
core +2 more sources
Nature Communications, 2019 Due to their poor electrophilicity, 2H-azirines do not easily react with nucleophiles. Here, the authors show an acidic activation of 2H-azirines by cyanoacetic acid coupling partners affording chiral aziridines containing vicinal tetrasubstituted and ...
Hai-Jun Zhang, Yan-Cheng Xie, Liang Yin
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3-Amino-2H-azirine, Moleküle mit vielfältigen Reaktionsmöglichkeiten
CHIMIA, 1979 3-Amino-2H-azirines, cyclic three-membered amidines with an estimated ring strain of about 200 kJ/mole, undergo a variety of reactions. Thereby, each of the azirine bonds can be broken: Thermolysis leads to the rupture of the C(2),C(3)-bond, with strong
Heinz Heimgartner
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