Results 31 to 40 of about 1,782 (182)

Stereoselective cycloaddition of 1-glucosyl-1,3-butadienes with tert-butyl 2H-azirine-3-carboxylate, glyoxylates and imines [PDF]

, 2003
Glucosyl dienes 1 have been reacted with the achiral 2H-azirine 4 and with glyoxylates, forming fused structures of type 5 and disaccharide-like compounds 7 with good to excellent selectivity.
Almeida, I. G., Alves, M. José, Fortes, A. Gil, Freitas, A. P.   +3 more
core   +1 more source

Acetyl oxime/azirine 1, 3-dipole and strategy for the regioselective synthesis of polysubstituted pyrroles via [3 + 2] cycloaddition with alkyne utilizing Fe2O3@cellulose catalyst

Results in Chemistry, 2021
Fe2O3@cellulose catalyzed regioselective [3 + 2] cycloaddition of acetyl oxime with alkynes via 2H‑azirines intermediate generated in situ in an aqueous ethanolic medium is described.
Kartikey Dhar Dwivedi, Bhupender Kumar, Marri Sameer Reddy, Biplob Borah, J. Nagendra Babu, L. Raju Chowhan   +5 more
doaj   +1 more source

Catalytic asymmetric synthesis of diazabicyclo[3.1.0]hexanes by 1,3-dipolar cycloaddition of azomethine ylides with azirines [PDF]

, 2021
Substituted 1,3-diazabicyclo[3.1.0]hexanes with two contiguous quaternary stereocentres are readily prepared by catalytic asymmetric [3+2] cycloaddition of α-substituted iminoesters with azirines.
Adrio, Javier, Carretero, Juan C., Díaz-Tendero, Sergio, Molina, Alba   +3 more
core   +1 more source

Domino reactions of 2H-azirines with acylketenes from furan-2,3-diones: Competition between the formation of ortho-fused and bridged heterocyclic systems

Beilstein Journal of Organic Chemistry, 2014
3-Aryl-2H-azirines react with acylketenes, generated by thermolysis of 5-arylfuran-2,3-diones, to give bridged 5,7-dioxa-1-azabicyclo[4.4.1]undeca-3,8-diene-2,10-diones and/or ortho-fused 6,6a,12,12a-tetrahydrobis[1,3]oxazino[3,2-a:3′,2′-d]pyrazine-4,10 ...
Alexander F. Khlebnikov, Mikhail S. Novikov, Viktoriia V. Pakalnis, Roman O. Iakovenko, Dmitry S. Yufit   +4 more
doaj   +1 more source

Electrocyclizations of Conjugated Azapolyenes Produced in Reactions of Azaheterocycles with Metal Carbenes

Organics, 2021
Conjugated azapolyenes (azabuta-1,3-dienes, aza-/diaza-/oxaza-/oxadiazahexa-1,3,5-trienes) are highly reactive in electrocyclization reactions, which makes them convenient precursors for the synthesis of a wide range of four-, five-, and six-membered ...
Nikolai V. Rostovskii, Mikhail S. Novikov, Alexander F. Khlebnikov   +2 more
doaj   +1 more source

Optically active aziridine esters by nucleophilic addition of nitrogen heterocycles to a chiral 2H-azirine-2-carboxylic ester [PDF]

, 2003
Chiral enriched ethyl 3-methyl-2H-azirine-2-carboxylate acts as an efficient alkylating agent for a variety of five membered aromatic nitrogen heterocycles.Fundação para a Ciência e Tecnologia - POCTI/32723/QUI/2000 ...
Alves, M. José, Fortes, A. Gil, Gonçalves, Luís F. F. F.   +2 more
core   +1 more source

Cycloaddition of methyl 2-(2,6-dichorophenyl)-2H-azirine-3-carboxylate to electron rich 2-azadienes [PDF]

, 2003
Tert-Butyldimethylsililoxy-2-aza-1,3-butadienes react with 2H-azirine 3 leading to Diels-Alder cycloadducts in moderate yields. The reactions are endo- and regio- selective with the azirine being added by its less hindered face. There is only one product
Alves, M. José, Durães, M. Miguel, Fortes, A. Gil   +2 more
core   +1 more source

Azirinium ylides from α-diazoketones and 2H-azirines on the route to 2H-1,4-oxazines: three-membered ring opening vs 1,5-cyclization

Beilstein Journal of Organic Chemistry, 2015
Strained azirinium ylides derived from 2H-azirines and α-diazoketones under Rh(II)-catalysis can undergo either irreversible ring opening across the N–C2 bond to 2-azabuta-1,3-dienes that further cyclize to 2H-1,4-oxazines or reversibly undergo a 1,5 ...
Nikolai V. Rostovskii, Mikhail S. Novikov, Alexander F. Khlebnikov, Galina L. Starova, Margarita S. Avdontseva   +4 more
doaj   +1 more source

Synthetic Strategies to Access Fluorinated Azoles. [PDF]

European J Org Chem
This review highlights recent synthetic strategies for introducing fluorine groups (mono‐, di‐, and trifluoromethylation) into 11 major azole classes, identifying research gaps to inform future innovations in materials science, medicinal chemistry, and biomedical research.
El-Gaber MKA, Djugovski M, Huang TY, Adhikari S, Roy S.   +4 more
europepmc   +2 more sources

Design and Synthesis of Stereogenic-at-Iron Complexes with Multidentate Ligands and Application in Asymmetric Catalysis [PDF]

, 2023
Asymmetric catalysis is an indispensable tool of great importance for the economic and sustainable synthesis of non-racemic chiral molecules. In addition to organic compounds and biomolecules, chiral transition metal complexes represent a pivotal pillar ...
Steinlandt, Philipp Stefan
core   +1 more source