Results 121 to 130 of about 57,959 (306)
Pinus‐derived membrane vesicles disrupt pathogenic metabolism in fungi
Needle‐derived vesicles from pine trees impair fungal metabolism and growth, offering a sustainable strategy to control pine pitch canker disease. Abstract Much of what we know about the biological impacts of vesicles (MVs) is derived from Arabidopsis thaliana.
S. Kunene +3 more
wiley +1 more source
ABSTRACT Acute myeloid leukemia (AML) in elderly patients presents a major therapeutic challenge, as many are deemed unfit for intensive chemotherapy due to age, comorbidities, or frailty. Venetoclax in combination with hypomethylating agents (HMA) has emerged as a standard‐of‐care for this population, yet outcomes remain heterogeneous and predictive ...
Ernesto Vigna +11 more
wiley +1 more source
Background: Oral candidiasis, caused by Candida albicans, is one of the most common infections in immunocompromised patients, especially in HIV+ individuals. Objective: The aims of this study were to evaluate the susceptibility of C. albicans isolates to
I Ashrafi Tamai +4 more
doaj
Background: Anti-mold azoles have improved the outcomes of invasive aspergillosis (IA) when used therapeutically, but they are extensively used as prophylaxis.
Hiba Dagher +10 more
doaj +1 more source
High-Pressure Synthesis of a Pentazolate Salt
The pentazolates, the last all-nitrogen members of the azole series, have been notoriously elusive for the last hundred years despite enormous efforts to make these compounds in either gas or condensed phases.
Crowhurst, Jonathan C. +5 more
core +4 more sources
Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae [PDF]
Azole-resistant strains of Aspergillus fumigatus have been detected and the underlying molecular mechanisms of resistance characterized. Point mutations in the cyp51A gene have been proved to be related to azole resistance in A.
Alcazar-Fuoli, L. +3 more
core
Azoles are the primary antifungal drugs used to treat infections caused by Aspergillus fumigatus. However, the emergence of azole resistance in A. fumigatus has become a global health concern despite the low proportion of resistant isolates in natural ...
Shu Chen +8 more
doaj +1 more source
Vaginal azoles versus oral fluconazole in treatment of recurrent vulvovaginal candidiasis [PDF]
Background: Vulvovaginal candidiasis (VVC) is a fungal infection of the vagina and vulva. It is usually caused by Candida albicans, however, occasionally other candida species are responsible. The optimal treatment of VVC has not yet been defined.
تلو, مهشید +3 more
core
Template directed incorporation of nucleotide mixtures using azole- nucleobase analogs [PDF]
Geoffrey C. Hoops
openalex +1 more source
Jaborandi (Pilocarpus microphyllus) essential oil is obtained by removal and characterization using GC‐MS, revealing γ‐cadinene and trans‐caryophyllene as major constituents. The oil exhibits biological activity, with antifungal action against Candida spp.
Juniel Cruz Silva +15 more
wiley +1 more source

