Results 121 to 130 of about 57,959 (306)

Pinus‐derived membrane vesicles disrupt pathogenic metabolism in fungi

open access: yesPlant Biology, EarlyView.
Needle‐derived vesicles from pine trees impair fungal metabolism and growth, offering a sustainable strategy to control pine pitch canker disease. Abstract Much of what we know about the biological impacts of vesicles (MVs) is derived from Arabidopsis thaliana.
S. Kunene   +3 more
wiley   +1 more source

Clinical Utility of Frailty Scoring in Elderly Acute Myeloid Leukemia Patients Treated With Venetoclax and Hypomethylating Agents

open access: yesEuropean Journal of Haematology, Volume 116, Issue 2, Page 160-168, February 2026.
ABSTRACT Acute myeloid leukemia (AML) in elderly patients presents a major therapeutic challenge, as many are deemed unfit for intensive chemotherapy due to age, comorbidities, or frailty. Venetoclax in combination with hypomethylating agents (HMA) has emerged as a standard‐of‐care for this population, yet outcomes remain heterogeneous and predictive ...
Ernesto Vigna   +11 more
wiley   +1 more source

Chemical Composition and Anti-candida Activity of Trachyspermum ammi Essential Oil on Azoles Resistant Candida albicans Isolates from Oral Cavity of HIV+ Patients

open access: yesJournal of Medicinal Plants, 2013
Background: Oral candidiasis, caused by Candida albicans, is one of the most common infections in immunocompromised patients, especially in HIV+ individuals. Objective: The aims of this study were to evaluate the susceptibility of C. albicans isolates to
I Ashrafi Tamai   +4 more
doaj  

Outcome Analysis of Breakthrough Invasive Aspergillosis on Anti-Mold Azole Prophylaxis and Treatment: 30-Year Experience in Hematologic Malignancy Patients

open access: yesJournal of Fungi
Background: Anti-mold azoles have improved the outcomes of invasive aspergillosis (IA) when used therapeutically, but they are extensively used as prophylaxis.
Hiba Dagher   +10 more
doaj   +1 more source

High-Pressure Synthesis of a Pentazolate Salt

open access: yes, 2016
The pentazolates, the last all-nitrogen members of the azole series, have been notoriously elusive for the last hundred years despite enormous efforts to make these compounds in either gas or condensed phases.
Crowhurst, Jonathan C.   +5 more
core   +4 more sources

Probing the role of point mutations in the cyp51A gene from Aspergillus fumigatus in the model yeast Saccharomyces cerevisiae [PDF]

open access: yes, 2017
Azole-resistant strains of Aspergillus fumigatus have been detected and the underlying molecular mechanisms of resistance characterized. Point mutations in the cyp51A gene have been proved to be related to azole resistance in A.
Alcazar-Fuoli, L.   +3 more
core  

Variability in competitive fitness among environmental and clinical azole-resistant Aspergillus fumigatus isolates

open access: yesmBio
Azoles are the primary antifungal drugs used to treat infections caused by Aspergillus fumigatus. However, the emergence of azole resistance in A. fumigatus has become a global health concern despite the low proportion of resistant isolates in natural ...
Shu Chen   +8 more
doaj   +1 more source

Vaginal azoles versus oral fluconazole in treatment of recurrent vulvovaginal candidiasis [PDF]

open access: yes
Background: Vulvovaginal candidiasis (VVC) is a fungal infection of the vagina and vulva. It is usually caused by Candida albicans, however, occasionally other candida species are responsible. The optimal treatment of VVC has not yet been defined.
تلو, مهشید   +3 more
core  

Cytotoxic and Antileishmanial Potential of Pilocarpus microphyllus Essential Oil: In Vitro and In Silico Study

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Jaborandi (Pilocarpus microphyllus) essential oil is obtained by removal and characterization using GC‐MS, revealing γ‐cadinene and trans‐caryophyllene as major constituents. The oil exhibits biological activity, with antifungal action against Candida spp.
Juniel Cruz Silva   +15 more
wiley   +1 more source

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