Results 91 to 100 of about 16,315 (211)

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Expression of Efflux Pumps and Fatty Acid Activator One Genes in Azole Resistant Candida Glabrata Isolated From Immunocompromised Patients

Acta Medica Iranica, 2016
Acquired azole resistance in opportunistic fungi causes severe clinical problems in immunosuppressed individuals. This study investigated the molecular mechanisms of azole resistance in clinical isolates of Candida glabrata.
Shirin Farahyar, Farideh Zaini, Parivash Kordbacheh, Sassan Rezaie, Mehraban Falahati, Mahin Safara, Reza Raoofian, Kamran Hatami, Masoumeh Mohebbi, Mansour Heidari   +9 more
doaj  

The addition of clotrimazole reduces but does not abrogate fungal dysbiosis during effective antibacterial therapy for canine otitis externa

Journal of Small Animal Practice, EarlyView.
Objectives Malassezia dysbiosis commonly occurs after successful piperacillin‐tazobactam monotherapy for canine bacterial otitis externa. The study objective was to compare antimicrobial outcomes in dogs with otitis treated with piperacillin‐tazobactam in combination with the antifungal drug clotrimazole with a previous cohort treated with piperacillin‐
G. Gallow, J. Juhola, E. A. Ferguson, A. Loeffler, A. Hendricks, S. M. Frosini, S. Williams, E. Brennan, R. Bond   +8 more
wiley   +1 more source

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

Molecular Microbiology, EarlyView.
During asexual blood‐stage development, P. falciparum Sec14 proteins display distinct localizations suggesting specialized roles in lipid exchange. PfSec14‐1 initially localizes to the nucleus before moving to the ER and Golgi alongside PfSec14‐4 during schizogony.
Florian Lauruol, Dominik Šťastný, J. Pedro Fernandez‐Murray, Christopher R. McMaster, Peter Griač, Dave Richard   +5 more
wiley   +1 more source

Comparision of MICs of some Iranian Herbal Essences Against Azole Resistance and Azole Susceptible of Candida Albicans

Journal of Medicinal Plants, 2008
Background: Candida albicans is the most important species, cause candida infections. The common forms of candidiasis are cutaneous and mucosal candidiasis, include oral (thrush), Vaginal candidiasis and onychomycosis.
F Katiraee, S Eidi, AR Bahonar, H Zarrinfar, AR Khosravi   +4 more
doaj  

Comparative genomics reveals lineage‐associated structural variation and diversification in a barley fungal pathogen

New Phytologist, EarlyView.
Genome‐wide copy‐number variation landscape highlights structural divergence across Puccinia hordei isolates and potentially links Cyp51 amplification to fungicide insensitivity. Summary Leaf rust, caused by Puccinia hordei, is a major barley disease worldwide.
Xiaohui Yu, Mumta Chhetri, Mafruha Hasan, Thomas H. Roberts, Peng Zhang, Robert F. Park, Yi Ding   +6 more
wiley   +1 more source

Pinus‐derived membrane vesicles disrupt pathogenic metabolism in fungi

Plant Biology, EarlyView.
Needle‐derived vesicles from pine trees impair fungal metabolism and growth, offering a sustainable strategy to control pine pitch canker disease. Abstract Much of what we know about the biological impacts of vesicles (MVs) is derived from Arabidopsis thaliana.
S. Kunene, T. J. Mmushi, E. Steenkamp, T. Motaung   +3 more
wiley   +1 more source

An epigenetic mechanism of azole tolerance facilitates acquired antifungal resistance in Aspergillus fumigatus

mBio
Antibiotic tolerance paves the way for acquired resistance in bacterial pathogens. However, the mechanisms of tolerance and its evolutionary role in acquired resistance in pathogenic fungi, and particularly in filamentous fungi, remain elusive.
Sandeep Vellanki, Nathan DeMichaelis, Catherine Liao, Jason E. Stajich, Robert A. Cramer   +4 more
doaj   +1 more source

Impact of Letermovir on Voriconazole Concentrations in Lung Transplant Patients

Transplant Infectious Disease, EarlyView.
Concomitant letermovir was associated with lower voriconazole exposure and reduced attainment of commonly used efficacy thresholds in lung transplant recipients. Routine therapeutic drug monitoring after letermovir initiation is recommended, and empiric voriconazole dose escalation may be needed to avoid subtherapeutic exposure. ABSTRACT Background The
Leah Georgiades, Sunish Shah, Erin K. McCreary, Fernanda Silveira, Raman Venkataramanan, Vignesh Vasudevan, Ryan M. Rivosecchi   +6 more
wiley   +1 more source

Invasive Fungal Infections in Heart Transplants: A 10‐Year, Single Centre Retrospective Cohort Study From Subtropical Australia

Transplant Infectious Disease, EarlyView.
In this 10‐year retrospective cohort study of heart transplant recipients in subtropical Australia, we characterize the incidence and microbiological profile of invasive fungal infections, highlighting the underappreciated burden of late‐onset and non‐Aspergillus mold infections and the potential underdiagnosis of polymicrobial disease.
Angus Lane, Karen Hay, John McNamara, Alex Chaudhuri, Andrew Burke, Robert Horvath, Maryam Khorramshahi Bayat, Kanthi Vemuri   +7 more
wiley   +1 more source