Results 71 to 80 of about 15,578 (196)

Emergence of Trichophyton indotineae in Switzerland (2014–2025): Clinical analysis and antifungal susceptibility

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner, Dennis D. Arnold, Philipp P. Bosshard   +2 more
wiley   +1 more source

An Erg11 lanosterol 14-α-demethylase-Arv1 complex is required for Candida albicans virulence.

PLoS ONE, 2020
Azole resistant fungal infections remain a health problem for the immune compromised. Current therapies are limited due to rises in new resistance mechanisms.
Michelle L Villasmil, Antonio Daniel Barbosa, Jessie Lee Cunningham, Symeon Siniossoglou, Joseph T Nickels   +4 more
doaj   +1 more source

Consensus‐based Guideline on tinea capitis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The consensus‐based guideline developed under the auspices of the German Dermatological Society (DDG) is intended to provide physicians with a structured framework for clinical decision‐making in the management of patients with tinea capitis and to contribute to improved diagnostic accuracy, treatment adherence, and prevention. Tinea capitis is
Peter Mayser, Dietrich Abeck, Philipp P. Bosshard, Jochen Brasch, Georg Daeschlein, Isaak Effendy, Yvonne Gräser, Peter Höger, Julia Huynh, Maria Kinberger, Annette Kolb‐Mäurer, Katharina Antonia Langen, Bartosz Malisiewicz, Alexander Nast, Hagen Ott, Christin Pelzer, Dieter Reinel, Martin Schaller, Silke Uhrlaß, Pietro Nenoff   +19 more
wiley   +1 more source

High Azole Resistance in Aspergillus fumigatus Isolates from Strawberry Fields, China, 2018

Emerging Infectious Diseases, 2020
In 2018, we conducted a cross-sectional study to investigate azole resistance in environmental Aspergillus fumigatus isolates obtained from different agricultural fields in China. Using 63 soil cores, we cultured for azole-resistant A.
Yong Chen, Fengshou Dong, Jingya Zhao, Hong Fan, Chunping Qin, Runan Li, Paul E. Verweij, Yongquan Zheng, Li Han   +8 more
doaj   +1 more source

Mental Health Disorders in End‐Stage Kidney Disease: A Narrative Review of Clinical Considerations for Integrated Management

Hemodialysis International, EarlyView.
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra, Jordan Fangue‐Nelon, Garima Singh   +2 more
wiley   +1 more source

Mechanisms of resistance to azole antifungals.

Acta Biochimica Polonica, 1995
Until the late eighties, clinical resistance to azole antifungals was a rare phenomenon. Only a few cases of resistance to ketoconazole were found in patients with chronic mucocutaneous candidiasis (CMC). The spread of AIDS and the widespread prophylactic and therapeutic use of the hydrophilic azole compound fluconazole resulted both in the selection ...
P, Marichal, H, Vanden Bossche
openaire   +3 more sources

Evolution of Dermatophytic Fungi: Anthropogenic and Biogenic Environmental Factors

International Journal of Dermatology, EarlyView.
ABSTRACT Climate change presents new challenges to dermatologic care, ranging from anthropogenic factors, such as pollution that select for extremotolerant and potentially antifungal‐resistant fungi, to biogenic factors that can drive zoonotic outbreaks, which have received increased attention since the SARS‐CoV‐2 pandemic.
Aditya K. Gupta, Tong Wang, Richard C. Summerbell   +2 more
wiley   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

Variability in competitive fitness among environmental and clinical azole-resistant Aspergillus fumigatus isolates

mBio
Azoles are the primary antifungal drugs used to treat infections caused by Aspergillus fumigatus. However, the emergence of azole resistance in A. fumigatus has become a global health concern despite the low proportion of resistant isolates in natural ...
Shu Chen, Guoxing Zhu, Huiping Lin, Jian Guo, Shuwen Deng, Wenjuan Wu, Gustavo H. Goldman, Ling Lu, Yuanwei Zhang   +8 more
doaj   +1 more source

Practical recommendations for seborrheic dermatitis management: An expert consensus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This modified Delphi study established expert consensus on Seborrheic Dermatitis management. Key findings prioritize combined topical antifungal and anti‐inflammatory therapy for both acute flares and long‐term maintenance. The consensus also provides a clear framework for escalating to systemic treatment in extensive or refractory cases.
L. Naldi, A. Kyrgidis, G. S. Tiplica, M. A. de Rie, D. Tatsis, P. Gisondi, D. Ioannides, O. Chosidow, M. Deleuran, the Delphi SD study experts   +9 more
wiley   +1 more source