Results 81 to 90 of about 16,315 (211)
ABSTRACT Introduction End stage kidney disease (ESKD) is associated with a high prevalence of depression and anxiety, arising from both biological factors and the psychosocial burden of chronic dialysis care. Approximately 25%–30% of dialysis patients experience clinically significant depressive symptoms when assessed by structured clinical interview ...
Kunal Malhotra +2 more
wiley +1 more source
Azole drug resistance in yeasts [PDF]
E M, Johnson, D W, Warnock
openaire +2 more sources
Land use and climate change are two major environmental pressures that interact to impact insect biodiversity. We compared the impacts of land use alone and of the interaction between land use and climate change on the five major insect orders. Most impacted were the Lepidoptera, showing 91% lower total abundance in sites of high‐intensity agriculture ...
Kyra Nancie Smith +10 more
wiley +1 more source
Evolution of Dermatophytic Fungi: Anthropogenic and Biogenic Environmental Factors
ABSTRACT Climate change presents new challenges to dermatologic care, ranging from anthropogenic factors, such as pollution that select for extremotolerant and potentially antifungal‐resistant fungi, to biogenic factors that can drive zoonotic outbreaks, which have received increased attention since the SARS‐CoV‐2 pandemic.
Aditya K. Gupta +2 more
wiley +1 more source
The widespread use of azole antifungals in agriculture and clinical settings has led to serious drug resistance. Overexpression of the azole drug target 14α-demethylase ERG11 (CYP51) is the most common fungal resistance mechanism.
Pengju Yu +7 more
doaj +1 more source
Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley +15 more
wiley +1 more source
Marian A Gerges,1 Yasmin Ahmed Fahmy,1 Thoraya Hosny,2 Nessma H Gandor,2 Sherif Y Mohammed,2 Tahia Mohamed Ahmed Mohamed,2 Nabila Elsayed Mousa Abdelmoteleb,3 Noura E Esmaeel1 1Medical Microbiology and Immunology Department, Faculty of Medicine, Zagazig ...
Gerges MA +7 more
doaj
Systemic treatment of cutaneous leishmaniasis: A systematic review and meta‐analysis
This systematic review and meta‐analysis assessed systemic treatments for cutaneous leishmaniasis across 83 studies and 4603 patients. Treatment efficacies of meglumine antimoniate, miltefosine, azoles, pentamidine, and liposomal amphotericin B varied by region and species. Miltefosine showed consistent evidence across multiple settings.
Maximilian Egg +10 more
wiley +1 more source
Consensus recommendations for Trichophyton indotineae: A modified Delphi study
A modified Delphi consensus for suspected terbinafine‐resistant T. indotineae: confirm dermatophytes with KOH microscopy/culture and species‐level PCR/ITS sequencing. Itraconazole is recommended as first‐line systemic therapy, with luliconazole 1% cream as a topical adjunct. Posaconazole may be considered if itraconazole fails, while keeping antifungal
Aditya K. Gupta +20 more
wiley +1 more source
Azole-resistant Aspergillus fumigatus in the Italian environment
Azole resistance in Aspergillus fumigatus environmental and clinical isolates is recognised as an emerging problem worldwide. Development of azole resistance may be environmentally driven because of the massive use of azole fungicides in agriculture. The mechanism of azole resistance is mostly related to mutations in the cyp51A gene.A.
Anna Prigitano +4 more
openaire +2 more sources

