Results 31 to 40 of about 30,341 (234)

Sensitivity towards DMI fungicides and haplotypic diversity of their CYP51 target in the Mycosphaerella graminicola population of Flanders [PDF]

, 2014
Septoria leaf blotch, caused by the fungus Mycosphaerella graminicola, is the most important wheat disease in Northwestern Europe, and is currently controlled by fungicide applications.
Curvers, Katrien, Gheysen, Godelieve, Haesaert, Geert, Kyndt, Tina, Pycke, Bart   +4 more
core   +1 more source

A Novel Environmental Azole Resistance Mutation in Aspergillus fumigatus and a Possible Role of Sexual Reproduction in Its Emergence

mBio, 2017
This study investigated the dynamics of Aspergillus fumigatus azole-resistant phenotypes in two compost heaps with contrasting azole exposures: azole free and azole exposed.
Jianhua Zhang, Eveline Snelders, Bas J. Zwaan, Sijmen E. Schoustra, Jacques F. Meis, Karin van Dijk, Ferry Hagen, Martha T. van der Beek, Greetje A. Kampinga, Jan Zoll, Willem J. G. Melchers, Paul E. Verweij, Alfons J. M. Debets   +12 more
doaj   +1 more source

Azole resistance inCandida

European Journal of Clinical Microbiology & Infectious Diseases, 1997
Resistance of Candida to azoles is an increasing problem. Susceptibility testing of Candida against fluconazole and ketoconazole is now feasible and desirable. Good correlation of resistance in vitro with clinical failure of fluconazole therapy has now been shown in mucosal candidiasis.
Denning, D.W., Baily, G.G., Hood, S.V.
openaire   +4 more sources

High-Level Pan-Azole-Resistant Aspergillosis [PDF]

Journal of Clinical Microbiology, 2015
ABSTRACT High-level pan-azole-resistant Aspergillus fumigatus was recovered from four patients with chronic lung disease. In one patient, the development of progressive resistance followed long-term azole therapy and switching between antifungal azoles.
Ingen, J. van, Lee, H.A.L. van der, Rijs, A.J.M.M., Snelders, E., Melchers, W.J.G., Verweij, P.E.   +5 more
openaire   +3 more sources

Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]

, 2017
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba, van der Lee, Henrich, Verweij, Paul, Warris, Adilia   +3 more
core   +1 more source

Azole-ResistantAspergillus fumigatus, Iran

Emerging Infectious Diseases, 2013
To the Editor: Aspergillus fumigatus causes a variety of diseases in humans. The drugs recommended for treatment of Aspergillus diseases are the mold-active azole antifungal drugs (1). However, a wide range of mutations in A. fumigatus confer azole resistance, which commonly involves modifications in the cyp51A gene (2), the target for azole antifungal
Seyedmousavi, S., Hashemi, S.J., Zibafar, E., Zoll, J., Hedayati, M.T., Mouton, J.W., Melchers, W.J.G., Verweij, P.E.   +7 more
openaire   +5 more sources

Azole Cross-Resistance in Aspergillus fumigatus [PDF]

Antimicrobial Agents and Chemotherapy, 2002
ABSTRACT We susceptibility tested 17 clinical isolates of Aspergillus fumigatus , for most of which MICs of itraconazole were elevated (MIC at which 50% of the isolates tested are inhibited, 16 μg/ml), against itraconazole, posaconazole, ravuconazole, and voriconazole.
Mosquera, J., Denning, D.W.
openaire   +3 more sources

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Impact of TR₃₄/L98H, TR₄₆/Y121F/T289A and TR₅₃ Alterations in Azole-Resistant Aspergillus fumigatus on Sterol Composition and Modifications after In Vitro Exposure to Itraconazole and Voriconazole

Microorganisms, 2022
Background: Sterols are the main components of fungal membranes. Inhibiting their biosynthesis is the mode of action of azole antifungal drugs that are widely used to treat fungal disease including aspergillosis.
Rose-Anne Lavergne, Marjorie Albassier, Jean-Benoît Hardouin, Carlos Alvarez-Moreno, Fabrice Pagniez, Florent Morio, Patrice Le Pape, Isabelle Ourliac-Garnier   +7 more
doaj   +1 more source

Sequencing the Major Mycosphaerella Pathogens of Wheat and Banana [PDF]

, 2009
Mycosphaerella is one of the largest genera of plant-pathogenic fungi with more than 1,000 named species, many of which are important pathogens causing leaf spotting diseases in a wide variety of crops including cereals, citrus, banana, eucalypts, soft ...
Kema, G.H.J.
core   +2 more sources