Results 31 to 40 of about 21,150 (298)

Meat and cancer: haemoglobin and haemin in a low calcium diet promote colorectal carcinogenesis at the aberrant crypt stage in rats [PDF]

, 2003
High intake of red meat, but not of white meat, is associated with an increased risk of colon cancer. However, red meat does not promote cancer in rodents.
Corpet, Denis E., Petit, Claude, Pierre, Fabrice, Taché, Sylviane, Van der Meer, Roleof   +4 more
core   +5 more sources

Induction of Colonic Aberrant Crypts in Mice by Feeding Apparent N-Nitroso Compounds Derived From Hot Dogs [PDF]

, 2012
Nitrite-preserved meats (e.g., hot dogs) may help cause colon cancer because they contain N-nitroso compounds. We tested whether purified hot-dog-derived total apparent N-nitroso compounds (ANC) could induce colonic aberrant crypts, which are putative ...
Caderni G, Denis E. Corpet, James L. Wisecarver, James M. Gulizia, Lin Zhou, McLellan E A, McLellan E A, McLellan E A, Michael E. Davis, Michal P. Lisowyj, Mirvish S S, Nathalie Naud, Newmark H L, Sidney S. Mirvish, Valerie K. Shostrom, Ward J M   +15 more
core   +5 more sources

Effect of Tarantula cubensis alcohol extract and Capecitabin combine in Colorectal Cancer rats

Revista Científica, 2023
Colon cancer (CRC) is one of the most common types of cancer in the world. In this study, the effects of Tarantula cubensis alcoholic extract (TCAE) and the Capecitabine in CRC were investigated. Wistar albino rats were divided into eight groups with 12
Rahmi Canbar, Ozgur Ozdemir, Ahmet Levent Bas   +2 more
doaj   +1 more source

Targeting Senescence: Tianma Granule Inhibits Colorectal Cancer Progression by Modulating miR-29a-5p/P53 Signaling in the Tumor Microenvironment. [PDF]

Mol Nutr Food Res
Tianma granule (TMG) inhibits colorectal cancer progression by modulating miR‐29a‐5p/P53 signaling in the tumor microenvironment, reducing stromal senescence and countering pro‐tumorigenic effects. ABSTRACT Chemotherapy‐induced senescence‐associated tumor microenvironment (S‐TME) facilitates colorectal cancer (CRC) progression.
Tang X, Ren Y, Li Y, Lv Y, Zhao L, He Y.
europepmc   +2 more sources

Beef meat promotion of dimethylhydrazine-induced colorectal carcinogenesis biomarkers is suppressed by dietary calcium [PDF]

, 2007
Red meat consumption is associated with increased risk of colorectal cancer. We have previously shown that haemin, Hb and red meat promote carcinogen-induced preneoplastic lesions: aberrant crypt foci (ACF) and mucin-depleted foci (MDF) in rats.
Corpet, Denis E., Guéraud, Françoise, Pierre, Fabrice, Santarelli, Raphaëlle L., Taché, Sylviane   +4 more
core   +4 more sources

Increased colon tumor susceptibility in azoxymethane treated CEABAC transgenic mice [PDF]

Carcinogenesis, 2006
Human carcinoembryonic antigen (CEA), a widely used clinical tumor marker, and its close relative, CEACAM6, are often overexpressed in many cancers. This correlation suggests a possible instrumental role in tumorigenesis, which is supported by extensive results obtained with several in vitro systems.
Carlos H F, Chan, Denise, Cook, Clifford P, Stanners   +2 more
openaire   +2 more sources

A Novel Mouse Model of Intrahepatic Cholangiocarcinoma Induced by Azoxymethane

International Journal of Molecular Sciences, 2023
Cholangiocarcinoma is the second most common primary cancer of the liver and has a poor prognosis. Various animal models, including carcinogen-induced and genetically engineered rodent models, have been established to clarify the mechanisms underlying cholangiocarcinoma development.
Yohei Shirakami, Junichi Kato, Masaya Ohnishi, Daisuke Taguchi, Toshihide Maeda, Takayasu Ideta, Masaya Kubota, Hiroyasu Sakai, Hiroyuki Tomita, Takuji Tanaka, Masahito Shimizu   +10 more
openaire   +2 more sources

Dietary Carbohydrates Modify Azoxymethane-Induced Intestinal Carcinogenesis in Rats ,

The Journal of Nutrition, 1994
The effect of different dietary carbohydrates (sucrose, cornstarch and high amylose cornstarch) on intestinal carcinogenesis was studied in male Sprague-Dawley rats treated subcutaneously with azoxymethane (AOM) at a weekly dose of 8 mg/kg body wt for 8 wk.
CADERNI, GIOVANNA, LUCERI, CRISTINA, M. T. Spagnesi, A. Giannini, BIGGERI, ANNIBALE, DOLARA, PIERO   +5 more
openaire   +4 more sources

Effect of Estradiol in an Azoxymethane/Dextran Sulfate Sodium-Treated Mouse Model of Colorectal Cancer: Implication for Sex Difference in Colorectal Cancer Development

Cancer research and treatment : official journal of Korean Cancer Association, 2018
Purpose This study demonstrates that estradiol downregulates inflammation and inhibits colorectal cancer (CRC) development in azoxymethane/dextran sulfate sodium (AOM/DSS) mouse model.
Hee-Jin Son, S. Sohn, Nayoung Kim, Ha-Na Lee, S. Lee, R. Nam, J. H. Park, Chin-Hee Song, E. Shin, H. Y. Na, J. S. Kim, D. H. Lee, Y. Surh   +12 more
semanticscholar   +1 more source

6-Bromoisatin Found in Muricid Mollusc Extracts Inhibits Colon Cancer Cell Proliferation and Induces Apoptosis, Preventing Early Stage Tumor Formation in a Colorectal Cancer Rodent Model

Marine Drugs, 2013
Muricid molluscs are a natural source of brominated isatin with anticancer activity. The aim of this study was to examine the safety and efficacy of synthetic 6-bromoisatin for reducing the risk of early stage colorectal tumor formation. The purity of 6-
Babak Esmaeelian, Catherine A. Abbott, Richard K. Le Leu, Kirsten Benkendorff   +3 more
doaj   +1 more source