Natural killer (NK) cells are an essential component of innate immunity against cancer development. Many studies have been conducted to evaluate immune-modulating effects using dietary compounds.
Pan Pan +10 more
doaj +1 more source
Deletion of glutathione peroxidase-2 inhibits azoxymethane-induced colon cancer development. [PDF]
The selenoprotein glutathione peroxidase-2 (GPx2) appears to have a dual role in carcinogenesis. While it protected mice from colon cancer in a model of inflammation-triggered carcinogenesis (azoxymethane and dextran sodium sulfate treatment), it ...
Mike F Müller +7 more
doaj +1 more source
Calcium Carbonate Suppresses Haem Toxicity Markers without Calcium Phosphate Side Effect on Colon Carcinogenesis [PDF]
Red meat intake is associated with increased risk of colorectal cancer. We have previously shown that haemin, haemoglobin and red meat promote carcinogen-induced preneoplastic lesions, aberrant crypt foci, in the colon of rats.
Belbraouet +14 more
core +5 more sources
Polyethylene glycol, unique among laxatives, suppresses aberrant crypt foci, by elimination of cells. [PDF]
OBJECTIVE: Polyethylene glycol (PEG), an osmotic laxative, is a potent inhibitor of colon cancer in rats. In a search for the underling mechanisms, the hypothesis that fecal bulking and moisture decrease colon carcinogenesis was tested.
Corpet, Denis E. +3 more
core +3 more sources
Colorectal cancer (CRC) is one of the most common cancers and a major cause of mortality. Mice with truncating Apc germline mutations have been used as a standard model of CRC, but most of the Apc-mutated lines develop multiple tumors in the proximal ...
Rebecca Metzger +4 more
doaj +1 more source
Processed Meat and Colorectal Cancer: A Review of Epidemiologic and Experimental Evidence [PDF]
Processed meat intake may be involved in the etiology of colorectal cancer, a major cause of death in affluent countries. The epidemiologic studies published to date conclude that the excess risk in the highest category of processed meat-eaters is ...
Corpet, Denis E. +2 more
core +4 more sources
Carbohydrate Digestibility Predicts Colon Carcinogenesis in Azoxymethane-Treated Rats
The purpose of this study was to compare the effect of carbohydrate structure and digestibility on azoxymethane (AOM)-induced colon carcinogenesis. Five groups of male Fischer 344 rats each comprising 30 animals were injected with AOM and fed a high-fat diet with 15% of various carbohydrates.
Jacobsen, Helene +5 more
openaire +2 more sources
Latarbelakang: Inflamasi merupakan salah satu faktor yang berperan penting dalam patofisiologi kanker kolorektal. Daun Carica pubescens yang mengandung flavonoid berpotensi sebagai agen preventif kanker kolorektal.
Maharani Shofa Yudina +2 more
doaj +1 more source
Gum arabic and red propolis protecteting colorectal preneoplastic lesions in a rat model of azoxymethane [PDF]
Purpose: To evaluate red propolis, gum arabic and L-lysine activity on colorectal preneoplastic lesions induced by azoxymethane (AOM). Methods: The study featured 4 control groups (I-IV) and 4 experimental groups (V-VIII), totaling 48 rats. Once a week
Vanessa Nogueira Lages Braga +7 more
doaj +1 more source
Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats [PDF]
Recent epidemiological studies suggest that high meat intake is associated with promotion of colon cancer linked to haem-iron intake. We previously reported that dietary haem, in the form of either haemoglobin or meat, promotes precancerous lesions in ...
Guéraud, Françoise +5 more
core +1 more source

