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Advances in tumor-infiltrating B lymphocytes [PDF]
In the landscape of tumor immunotherapy, T cell-mediated immune responses have consistently captured the attention, while the contributions of B cells have been neglected.
Yule Zhang +4 more
doaj +2 more sources
Tyrosine Kinase Inhibitors Target B Lymphocytes [PDF]
Autoimmune disorders and some types of blood cancer originate when B lymphocytes malfunction. In particular, when B cells produce antibodies recognizing the body’s proteins, it leads to various autoimmune disorders.
Nikki Lyn Esnardo Upfold +3 more
doaj +2 more sources
B Lymphocytes in Parkinson’s Disease [PDF]
It is well known that B lymphocytes differentiate into plasma cells that produce antibodies. B cells also perform a number of less well-known roles including antigen presentation, regulation of T cells and innate immune cells, cytokine production, and maintenance of subcapsular sinus macrophages.
Scott KM.
openaire +4 more sources
Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research
Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais +5 more
doaj +1 more source
CD20 and CD19 targeted vectors induce minimal activation of resting B lymphocytes [PDF]
B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors ...
A Pezzutto +51 more
core +11 more sources
Persistent inflammation can promote the development of tertiary lymphoid structures (TLS) within tissues resembling secondary lymphoid organs (SLO) such as lymph nodes (LN).
Marion Le Rochais +10 more
doaj +1 more source
Could AMPs and B-cells be the missing link in understanding periodontitis?
Periodontal diseases are common inflammatory conditions characterized by bone loss in response to simultaneous bacterial aggression and host defenses. The etiology of such diseases is still not completely understood, however.
Vanessa Dominique Lobognon +2 more
doaj +1 more source
IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates
Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot +9 more
doaj +1 more source
Immunopathogenesis of childhood idiopathic nephrotic syndrome [PDF]
Pediatric nephrotic syndrome (NS) is a clinical syndrome characterized by massive proteinuria, hypoalbuminemia, and generalized edema. Most childhood NS cases are idiopathic (with an unknown etiology).
Hae Il Cheong
doaj +1 more source
Rheumatological features of Whipple disease
Whipple disease (WD) is a rare infectious systemic disease. Rheumatologists are at the frontline of WD diagnosis due to the early rheumatological manifestations. An early diagnosis is crucial, as usual anti-rheumatic drugs, especially TNF inhibitors, may
Alice Tison +16 more
doaj +1 more source

