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Tyrosine Kinase Inhibitors Target B Lymphocytes [PDF]
Biomolecules, 2023 Autoimmune disorders and some types of blood cancer originate when B lymphocytes malfunction. In particular, when B cells produce antibodies recognizing the body’s proteins, it leads to various autoimmune disorders.
Nikki Lyn Esnardo Upfold +3 more
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B Lymphocytes in Parkinson's Disease. [PDF]
J Parkinsons Dis, 2022 It is well known that B lymphocytes differentiate into plasma cells that produce antibodies. B cells also perform a number of less well-known roles including antigen presentation, regulation of T cells and innate immune cells, cytokine production, and maintenance of subcapsular sinus macrophages.
Scott KM.
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Application of High-Throughput Imaging Mass Cytometry Hyperion in Cancer Research
Frontiers in Immunology, 2022 Imaging mass cytometry (IMC) enables the in situ analysis of in-depth-phenotyped cells in their native microenvironment within the preserved architecture of a single tissue section.
Marion Le Rochais +5 more
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Frontiers in Immunology, 2023 Persistent inflammation can promote the development of tertiary lymphoid structures (TLS) within tissues resembling secondary lymphoid organs (SLO) such as lymph nodes (LN).
Marion Le Rochais +10 more
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Could AMPs and B-cells be the missing link in understanding periodontitis?
Frontiers in Immunology, 2022 Periodontal diseases are common inflammatory conditions characterized by bone loss in response to simultaneous bacterial aggression and host defenses. The etiology of such diseases is still not completely understood, however.
Vanessa Dominique Lobognon +2 more
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IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates
Frontiers in Immunology, 2021 Mucosal immune responses are crucial in protecting against pathogens entering through mucosal surfaces. However, due to poor T-cell responsiveness upon mucosal antigenic stimulation, mucosal immunity remains difficult to obtain through vaccines and ...
Sandrine Logerot +9 more
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Rheumatological features of Whipple disease
Scientific Reports, 2021 Whipple disease (WD) is a rare infectious systemic disease. Rheumatologists are at the frontline of WD diagnosis due to the early rheumatological manifestations. An early diagnosis is crucial, as usual anti-rheumatic drugs, especially TNF inhibitors, may
Alice Tison +16 more
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Marine Drugs, 2021 Ciguatera fish poisoning (CFP) and neurotoxic shellfish poisoning syndromes are induced by the consumption of seafood contaminated by ciguatoxins and brevetoxins.
Ophélie Pierre +9 more
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STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia
Journal for ImmunoTherapy of Cancer, 2019 Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly described ...
Marjolaine Debant +14 more
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Вісник медичних і біологічних досліджень, 2022 Sumarry. To date, the issue of finding out the specifics of changes in the immune system under the conditions of allergic alveolitis and immobilization stress remains unexplored, since these diseases are quite widespread.
M.S. Regeda, V.V. Galii-Lutska
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