Results 11 to 20 of about 14,096,305 (385)

CD20 and CD19 targeted vectors induce minimal activation of resting B lymphocytes [PDF]

, 2013
B lymphocytes are an important cell population of the immune system. However, until recently it was not possible to transduce resting B lymphocytes with retro- or lentiviral vectors, making them unsusceptible for genetic manipulations by these vectors ...
A Pezzutto, A Yoder, AD Bucheit, B Anliker, C Demaison, C Frecha, C Frecha, C Frecha, CA Walshe, Christian J. Buchholz, CJ Buchholz, D Unutmaz, DA Tuveson, DD Sloan, Els Verhoeyen, Evren Alici, François-Loic Cosset, H Li, H Niiro, J Bruenke, J Uchida, JT Golay, K Akashi, K Itoh, L Ginaldi, M Fujimoto, M Kügler, M Peipp, M Serafini, M Zanetti, MD Mühlebach, Michael Schwenkert, MJ Polyak, MS Cragg, NE Harwood, Q Zhou, Q Zhou, Q Zhou, Qi Zhou, R Zufferey, RC Münch, RN Damle, RS Noyce, S Funke, S Kheirallah, S Kneissl, Sabrina Kneissl, T Nakamura, TF Tedder, X Li, Y Reiter, YD Korin   +51 more
core   +11 more sources

CD4+ T cells reverse surface antigen persistence in a mouse model of HBV replication

Microbiology Spectrum, 2023
Hepatitis B virus (HBV) is responsible for over 800,000 deaths yearly worldwide. While chronic HBV infection currently has no highly effective cure, immunotherapy has generated interest as a potential therapeutic solution due to the connection between ...
Jacob T. Bailey, Safiehkhatoon Moshkani, Catherine Rexhouse, Jesse L. Cimino, Michael D. Robek   +4 more
doaj   +1 more source

Discrimination of human cytotoxic lymphocytes from regulatory and B-lymphocytes by orthogonal light scattering [PDF]

, 1986
Light scattering properties of human lymphocyte subpopulations selected by immunofluorescence were studied with a flow cytometer. Regulatory and B-lymphocytes showed a low orthogonal light scatter signal, whereas cytotoxic lymphocytes identified with leu-
Berkel, W. van, Greve, J., Grooth, B.G. de, Napel, C.H.H. ten, Terstappen, L.W.M.M.   +4 more
core   +9 more sources

STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Background Dysregulation in calcium (Ca2+) signaling is a hallmark of chronic lymphocytic leukemia (CLL). While the role of the B cell receptor (BCR) Ca2+ pathway has been associated with disease progression, the importance of the newly described ...
Marjolaine Debant, Miguel Burgos, Patrice Hemon, Paul Buscaglia, Tinhinane Fali, Sarra Melayah, Nelig Le Goux, Christophe Vandier, Marie Potier-Cartereau, Jacques-Olivier Pers, Adrian Tempescul, Christian Berthou, Cristina Bagacean, Olivier Mignen, Yves Renaudineau   +14 more
doaj   +1 more source

Inflammation is responsible for systemic bone loss in patients with seropositive rheumatoid arthritis treated with rituximab [PDF]

The Korean Journal of Internal Medicine, 2023
Background/Aims We investigated the effect of rituximab on systemic bone metabolism in patients with seropositive rheumatoid arthritis (RA). Methods Twenty seropositive patients with RA were enrolled and administered one cycle of rituximab.
Mie Jin Lim, Kyong-Hee Jung, Seong-Ryul Kwon, Won Park   +3 more
doaj   +1 more source

B lymphocytes secrete antigen-presenting vesicles

Journal of Experimental Medicine, 1996
Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II- enriched compartment), that harbors newly synthesized MHC class II molecules in transit to the plasma membrane. MIICs have a
G. Raposo, H. Nijman, W. Stoorvogel, R. Liejendekker, C. Harding, C. Melief, H. Geuze   +6 more
semanticscholar   +1 more source

Simulated patient and role play methodologies for communication skills and empathy training of undergraduate medical students

BMC Medical Education, 2020
Background Verbal and non-verbal communication, as well as empathy are central to patient-doctor interactions and have been associated with patients’ satisfaction. Non-verbal communication tends to override verbal messages.
Cristina Bagacean, Ianis Cousin, Anne-Helene Ubertini, Mohamed El Yacoubi El Idrissi, Anne Bordron, Lolita Mercadie, Leonor Canales Garcia, Jean-Christophe Ianotto, Philine De Vries, Christian Berthou   +9 more
doaj   +1 more source

CLINICAL AND LABORATORY FEATURES OF THE IMMUNE RESPONSE IN CHILDREN WITH COVID-19 INFECTION

Siberian Journal of Life Sciences and Agriculture, 2023
The article presents the results of the analysis of clinical and morphological characteristics and a number of indicators of peripheral blood in children with a new coronavirus infection.
Elizaveta S. Ageeva, Natalya V. Rymarenko, Elena N. Dyadyura, Anna K. Gurtovaya, Sergey L. Safronyuk, Remzie N. Ablaeva, Svetlana V. Usova   +6 more
doaj   +1 more source

SURFACE MARKERS ON HUMAN T AND B LYMPHOCYTES

Journal of Experimental Medicine, 1972
By using the two criteria (a) high density of immunoglobulin determinants on the cell surface and (b) presence of receptors for C'3 on the cell surface for defining bone marrow-derived lymphocytes, it is indirectly shown that all or at least a major ...
M. Jondal, G. Holm, H. Wigzell
semanticscholar   +1 more source

Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance Spontaneous accumulation of somatic DNA mutations has been hypothesized as a cause of both cancer and aging. However, detecting mutations in normal, noncancer cells is challenging, because mutations accumulate independently in each cell ...
Lei Zhang, Xiao Dong, Moonsook Lee, A. Maslov, Tao Wang, J. Vijg   +5 more
semanticscholar   +1 more source