Results 21 to 30 of about 754,020 (340)

Monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by CD5+ B cells from patients with rheumatoid arthritis. [PDF]

, 1988
In patients with rheumatoid arthritis (RA), circulating CD5+ B lymphocytes, but not CD5- B lymphocytes, are increased in number and size, exist in an activated state, spontaneously proliferate, and secrete Ig that binds to the Fc fragment of IgG.
Burastero, SE, Casali, P, Notkins, AL, Wilder, RL   +3 more
core   +1 more source

17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades in this pathology, when used in combination with chemotherapy ...
Cristina Bagacean, Adrian Tempescul, David Ternant, Anne Banet, Nathalie Douet-Guilbert, Anne Bordron, Boutahar Bendaoud, Hussam Saad, Mihnea Zdrenghea, Christian Berthou, Gilles Paintaud, Yves Renaudineau   +11 more
doaj   +1 more source

Inflammation is responsible for systemic bone loss in patients with seropositive rheumatoid arthritis treated with rituximab [PDF]

The Korean Journal of Internal Medicine, 2023
Background/Aims We investigated the effect of rituximab on systemic bone metabolism in patients with seropositive rheumatoid arthritis (RA). Methods Twenty seropositive patients with RA were enrolled and administered one cycle of rituximab.
Mie Jin Lim, Kyong-Hee Jung, Seong-Ryul Kwon, Won Park   +3 more
doaj   +1 more source

B lymphocytes in neuromyelitis optica [PDF]

Neurology Neuroimmunology & Neuroinflammation, 2015
Neuromyelitis optica (NMO) is an inflammatory autoimmune disorder of the CNS that predominantly affects the spinal cord and optic nerves. A majority (approximately 75%) of patients with NMO are seropositive for autoantibodies against the astrocyte water channel aquaporin-4 (AQP4).
Bennett, Jeffrey L., O'Connor, Kevin C., Bar-Or, Amit, Zamvil, Scott S., Hemmer, Bernhard, Tedder, Thomas F., von Büdingen, H-Christian, Stuve, Olaf, Yeaman, Michael R., Smith, Terry J., Stadelmann, Christine   +10 more
openaire   +5 more sources

Morphologic observations of human T and B lymphocytes by scanning electron microscopy [PDF]

, 1974
T cell concerned with cell mediated immunity and B cell concerned with humoral antibody are classified by scanning electron microscopy of the surface structure of lymphocytes using E binding lymphocytes and EAC (sensitized sheep erythrocytes treated with
Yamamoto, Isamu
core   +1 more source

JAK Inhibitors and Oxidative Stress Control

Frontiers in Immunology, 2019
Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras, Pinelopi Arvaniti, Pinelopi Arvaniti, Pinelopi Arvaniti, Christelle Le Dantec, George N. Dalekos, George N. Dalekos, Kaliopi Zachou, Kaliopi Zachou, Anne Bordron, Yves Renaudineau, Yves Renaudineau   +11 more
doaj   +1 more source

CLINICAL AND LABORATORY FEATURES OF THE IMMUNE RESPONSE IN CHILDREN WITH COVID-19 INFECTION

Siberian Journal of Life Sciences and Agriculture, 2023
The article presents the results of the analysis of clinical and morphological characteristics and a number of indicators of peripheral blood in children with a new coronavirus infection.
Elizaveta S. Ageeva, Natalya V. Rymarenko, Elena N. Dyadyura, Anna K. Gurtovaya, Sergey L. Safronyuk, Remzie N. Ablaeva, Svetlana V. Usova   +6 more
doaj   +1 more source

Expression of CXCR4 on feline peripheral blood mononuclear cells: effect of feline immunodeficiency virus infection. [PDF]

, 2003
CXCR4 expression on feline peripheral blood mononuclear cells (PBMC) was analyzed. While monocytes and B lymphocytes expressed CXCR4, no CXCR4 was detected on T lymphocytes, in stark contrast to the expression pattern on T lymphocytes from humans.
Cannon, C.A., Hosie, M.J., Willett, B.J.
core   +2 more sources

High Ki67 proliferation index but not cell-of-origin subtypes is associated with shorter overall survival in diffuse large B-cell lymphoma

Avicenna Journal of Medicine, 2020
Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome.
Feras Zaiem, Rada Jerbi, Omar Albanyan, Jordyn Puccio, Zyad Kafri, Jay Yang, Ali M Gabali   +6 more
doaj   +1 more source

Correlation Between Immune Function Status and EBV DNA in Patients with Nasopharyngeal Carcinoma and Their Influence on Prognosis

Zhongliu Fangzhi Yanjiu, 2021
Objective To explore the correlation between EBV DNA load and peripheral immune cells (including lymphocyte supsets and natural killer cells) before treatment in patients with NPC, and analyze the influence of circulating immune cell supsets related to ...
WEI Xueling, LAN Mei, PENG Xinhao, ZHANG Hanyi, LONG En, LIU Hui, LANG Jinyi   +6 more
doaj   +1 more source