Results 21 to 30 of about 637,016 (303)
Iatreia, 2022 Rheumatoid Arthritis (RA) is a common autoimmune disease characterized by chronic inflammation in the joints that can progress to bone destruction. Although the pathophysiology of RA is unclear, T cells and B cells are though to be involved.
Segura-González, Angie Katherine +3 more
doaj +1 more source
B lymphocytes in neuromyelitis optica [PDF]
Neurology Neuroimmunology & Neuroinflammation, 2015 Neuromyelitis optica (NMO) is an inflammatory autoimmune disorder of the CNS that predominantly affects the spinal cord and optic nerves. A majority (approximately 75%) of patients with NMO are seropositive for autoantibodies against the astrocyte water channel aquaporin-4 (AQP4).
Bennett, Jeffrey L. +10 more
openaire +5 more sources
JAK Inhibitors and Oxidative Stress Control
Frontiers in Immunology, 2019 Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras +11 more
doaj +1 more source
Inflammation is responsible for systemic bone loss in patients with seropositive rheumatoid arthritis treated with rituximab [PDF]
The Korean Journal of Internal Medicine, 2023 Background/Aims We investigated the effect of rituximab on systemic bone metabolism in patients with seropositive rheumatoid arthritis (RA). Methods Twenty seropositive patients with RA were enrolled and administered one cycle of rituximab.
Mie Jin Lim +3 more
doaj +1 more source
Инфекция и иммунитет, 2021 The aim of the study was to identify a relationship between gene polymorphisms associated with developing coronary heart disease and pathogenetic features of opisthorchiasis invasion.
S. A. Grigoryeva +6 more
doaj +1 more source
Ontogeny of mouse B lymphocytes and inactivation by antigen of early B lymphocytes. [PDF]
Proceedings of the National Academy of Sciences, 1976 Taking advantage of recent findings about membrane fluidity, we have studied and compared the biosynthetic capacities of fetal or neonatal mouse B (bone-marrow derived) lymphocytes (until 10 days after birth) and adult B lymphocytes. Although both early and adult lymphocytes can synthesize surface immunoglobulins, they have a different physiological ...
Bruyns, C +4 more
openaire +3 more sources
Medicine Science, 2023 Kyrgyzstan's challenging natural conditions and fragile mountain ecosystems can weaken the immune system of individuals residing permanently in high-altitude areas.
Nasira Tiumonbaeva +3 more
doaj +1 more source
Contribution of B-lymphocytes to the production of Interleukin-17 in multiple sclerosis
Неврология, нейропсихиатрия, психосоматика, 2023 The study of pathogenic systems involved in multiple sclerosis (MS) is essential for the development of new therapies.Objective: to determine the contribution of B-lymphocytes to the production of IL-17 in MS with an assessment of the ability of B-cells ...
N. V. Sursyakova +4 more
doaj +1 more source
Arthritis Research & Therapy, 2017 Background The objective was to evaluate concordance between 2002 American-European Consensus Group (AECG) and 2016 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for primary Sjögren’s syndrome ...
Maëlle Le Goff +13 more
doaj +1 more source
The role of laboratory biomarkers in monitoring of rituximab biosimilar therapy (Acellbia, “BIOCAD”) in patients with rheumatoid arthritis [PDF]
Терапевтический архив, 2019 Aim: to evaluate the role of laboratory biomarkers in monitoring effectiveness of rituximab (RTM) biosimilar therapy in a total dose of 1200 mg. Materials and methods.
A S Avdeeva +7 more
doaj +1 more source