Results 21 to 30 of about 14,976,308 (290)

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

Cells, 2020
Red tides involving Karenia brevis expose humans to brevetoxins (PbTxs). Oral exposition triggers neurotoxic shellfish poisoning, whereas inhalation induces a respiratory syndrome and sensory disturbances.
Ophélie Pierre, Maxime Fouchard, Paul Buscaglia, Nelig Le Goux, Raphaël Leschiera, Olivier Mignen, Joachim W. Fluhr, Laurent Misery, Raphaële Le Garrec   +8 more
doaj   +1 more source

Epstein–Barr virus reprograms human B lymphocytes immediately in the prelatent phase of infection

Proceedings of the National Academy of Sciences of the United States of America, 2018
Significance More than 50 years ago, Epstein–Barr virus (EBV) was found to infect resting human B lymphocytes and to induce their continuous proliferation in vitro.
Paulina Mrozek-Gorska, Alexander Buschle, D. Pich, T. Schwarzmayr, R. Fechtner, A. Scialdone, W. Hammerschmidt   +6 more
semanticscholar   +1 more source

CD5+ B Lymphocytes

Experimental Biology and Medicine, 1991
SummaryA major proportion of CD5+ B lymphocytes are committed to the production of a discrete type of antibody that is polyreactive. Polyreactive antibodies appear to use selected V and, perhaps, D gene segments, mostly in unmutated configuration. They generally display relatively low affinity for different antigens and are often part of the primary ...
M T, Kasaian, H, Ikematsu, P, Casali
openaire   +2 more sources

Mesenchymal Stromal Cell-Derived Exosomes Affect mRNA Expression and Function of B-Lymphocytes

Frontiers in Immunology, 2018
Background: Bone marrow mesenchymal stem cells (bmMSC) may play a role in the regulation of maturation, proliferation, and functional activation of lymphocytes, though the exact mechanisms are unknown. MSC-derived exosomes induce a regulatory response in
Drirh Khare, R. Or, I. Resnick, C. Barkatz, O. Almogi-Hazan, B. Avni   +5 more
semanticscholar   +1 more source

17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia

Journal for ImmunoTherapy of Cancer, 2019
Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades in this pathology, when used in combination with chemotherapy ...
Cristina Bagacean, Adrian Tempescul, David Ternant, Anne Banet, Nathalie Douet-Guilbert, Anne Bordron, Boutahar Bendaoud, Hussam Saad, Mihnea Zdrenghea, Christian Berthou, Gilles Paintaud, Yves Renaudineau   +11 more
doaj   +1 more source

JAK Inhibitors and Oxidative Stress Control

Frontiers in Immunology, 2019
Primary Sjögren's syndrome (SjS) is a complex autoimmune epithelitis, with few treatment options, but the use of Janus kinase (JAK) inhibitors is promising because suppression of the JAK/signal transducer and activator of transcription (STAT) pathway ...
Amandine Charras, Pinelopi Arvaniti, Pinelopi Arvaniti, Pinelopi Arvaniti, Christelle Le Dantec, George N. Dalekos, George N. Dalekos, Kaliopi Zachou, Kaliopi Zachou, Anne Bordron, Yves Renaudineau, Yves Renaudineau   +11 more
doaj   +1 more source

High Ki67 proliferation index but not cell-of-origin subtypes is associated with shorter overall survival in diffuse large B-cell lymphoma

Avicenna Journal of Medicine, 2020
Background: CD10, BCL6, and MUM1 are commonly used immunohistochemical stains for classifying diffuse large B-cell lymphoma (DLBCL), which is useful in predicting outcome.
Feras Zaiem, Rada Jerbi, Omar Albanyan, Jordyn Puccio, Zyad Kafri, Jay Yang, Ali M Gabali   +6 more
doaj   +1 more source

CLINICAL AND LABORATORY FEATURES OF THE IMMUNE RESPONSE IN CHILDREN WITH COVID-19 INFECTION

Siberian Journal of Life Sciences and Agriculture, 2023
The article presents the results of the analysis of clinical and morphological characteristics and a number of indicators of peripheral blood in children with a new coronavirus infection.
Elizaveta S. Ageeva, Natalya V. Rymarenko, Elena N. Dyadyura, Anna K. Gurtovaya, Sergey L. Safronyuk, Remzie N. Ablaeva, Svetlana V. Usova   +6 more
doaj   +1 more source

B Lymphocytes in Rheumatoid Arthritis and the Effects of Anti-TNF-α Agents on B Lymphocytes: A Review of the Literature.

Clinical Therapeutics, 2018
PURPOSE The aim of this article was to review published research related to B lymphocytes in rheumatoid arthritis, their role in the pathogenesis of the disease, the effects of tumor necrosis factor (TNF)-α inhibitors on B lymphocytes, the risk for ...
O. Pala, A. Díaz, B. Blomberg, D. Frasca   +3 more
semanticscholar   +1 more source

Correlation Between Immune Function Status and EBV DNA in Patients with Nasopharyngeal Carcinoma and Their Influence on Prognosis

Zhongliu Fangzhi Yanjiu, 2021
Objective To explore the correlation between EBV DNA load and peripheral immune cells (including lymphocyte supsets and natural killer cells) before treatment in patients with NPC, and analyze the influence of circulating immune cell supsets related to ...
WEI Xueling, LAN Mei, PENG Xinhao, ZHANG Hanyi, LONG En, LIU Hui, LANG Jinyi   +6 more
doaj   +1 more source