Ontogeny of mouse B lymphocytes and inactivation by antigen of early B lymphocytes. [PDF]
Taking advantage of recent findings about membrane fluidity, we have studied and compared the biosynthetic capacities of fetal or neonatal mouse B (bone-marrow derived) lymphocytes (until 10 days after birth) and adult B lymphocytes. Although both early and adult lymphocytes can synthesize surface immunoglobulins, they have a different physiological ...
Bruyns, C +4 more
openaire +3 more sources
DR-bearing T lymphocytes in thoracic duct lymph [PDF]
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo +25 more
core +1 more source
CD4+ T cells reverse surface antigen persistence in a mouse model of HBV replication
Hepatitis B virus (HBV) is responsible for over 800,000 deaths yearly worldwide. While chronic HBV infection currently has no highly effective cure, immunotherapy has generated interest as a potential therapeutic solution due to the connection between ...
Jacob T. Bailey +4 more
doaj +1 more source
Epigenome-wide profiling identifies significant differences in DNA methylation between matched-pairs of T- and B-lymphocytes from healthy individuals [PDF]
Multiple reports now describe changes to the DNA methylome in rheumatoid arthritis and in many cases have analyzed methylation in mixed cell populations from whole blood.
Dawes, Peter T. +8 more
core +2 more sources
Phosphorylation of androgen receptors at serine 515 is a potential prognostic marker for triple negative breast cancer [PDF]
1.7 million cases of breast cancer are diagnosed every year with 522,000 deaths. Molecular classifications of breast cancer have resulted in improved treatments. However, treatments for triple negative breast cancer (TNBC) are lacking.
Edwards, Joanne +6 more
core +2 more sources
Background The objective was to evaluate concordance between 2002 American-European Consensus Group (AECG) and 2016 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) classification criteria for primary Sjögren’s syndrome ...
Maëlle Le Goff +13 more
doaj +1 more source
Adhesion and transcellular migration of neutrophils and B lymphocytes on fibroblasts [PDF]
During tissue inflammation, infiltrated leukocytes may have physical contacts with fibroblasts. We observed that neutrophils and B lymphocytes adhered in a larger proportion than T cells on cultured fibroblasts.
Couture, Patrick +3 more
core +2 more sources
Polyclonal and monoclonal B lymphocytes response in HCV-infected patients treated with direct-acting antiviral agents [PDF]
Hepatitis C virus (HCV) chronic infection can be associated with extrahepatic manifestations such as mixed cryoglobulinaemia and lymphoproliferative disorders that are endowed with increased rates of morbidity and all-cause mortality.
Burra, Patrizia +13 more
core +1 more source
Randomly Evolving Idiotypic Networks: Structural Properties and Architecture
We consider a minimalistic dynamic model of the idiotypic network of B-lymphocytes. A network node represents a population of B-lymphocytes of the same specificity (idiotype), which is encoded by a bitstring.
A. Ilachinsky +24 more
core +1 more source
Coupling imaging mass cytometry with Alcian blue histochemical staining for a single-slide approach
Imaging mass cytometry (IMC) is a metal mass spectrometry-based method allowing highly multiplex immunophenotyping of cells within tissue samples. However, some limitations of IMC are its 1-µm resolution and its time and costs of analysis limiting ...
Patrice Hemon +11 more
doaj +1 more source

