Effect of Rosmarinic Acid and Ionizing Radiation on Glutathione in Melanoma B16F10 Cells: A Translational Opportunity [PDF]
To explain a paradoxical radiosensitizing effect of rosmarinic acid (RA) on the melanoma B16F10 cells, we analyzed the glutathione (GSH) intracellular production on this cell (traditionally considered radioresistant) in comparison with human prostate ...
Amparo Olivares +3 more
doaj +4 more sources
Syringetin Promotes Melanogenesis in B16F10 Cells. [PDF]
Syringetin, an active compound present in red grapes, jambolan fruits, Lysimachia congestiflora, and Vaccinium ashei, is a dimethyl myricetin derivative which contains free hydroxyl groups at the C-2′ and C-4′ positions in ring B. Recent studies have revealed that syringetin possesses multiple pharmacological properties, such as antitumor ...
Han H, Hyun CG.
europepmc +3 more sources
Dimethyl Itaconate Inhibits Melanogenesis in B16F10 Cells. [PDF]
Itaconate is a metabolite produced to counteract and resolve pro-inflammatory responses when macrophages are challenged with intracellular or extracellular stimuli. In the present study, we have observed that dimethyl itaconate (DMI) inhibits melanogenesis in B16F10 cells.
Yu BY, Ngo HH, Choi WJ, Keum YS.
europepmc +4 more sources
Chamaejasmin B Decreases Malignant Characteristics of Mouse Melanoma B16F0 and B16F10 Cells [PDF]
Chamaejasmin B (CHB), a natural biflavone isolated from Stellera chamaejasme L., has been reported to exhibit anti-cancer properties; however, its effect in melanoma cells is not clear.
Lingling Si +10 more
doaj +2 more sources
Echinochrome A Inhibits Melanogenesis in B16F10 Cells by Downregulating CREB Signaling. [PDF]
Excessive increase in melanin pigment in the skin can be caused by a variety of environmental factors, including UV radiation, and can result in spots, freckles, and skin cancer. Therefore, it is important to develop functional whitening cosmetic reagents that regulate melanogenesis.
Choi MR +11 more
europepmc +4 more sources
Effects of heavy ions (12C6+) on malignant melanoma B16F10 cells. [PDF]
This study aimed to investigate the effects of heavy ion (12C6+) irradiation on the proliferation, apoptosis, cell cycle, migration, and epithelial-mesenchymal transition (EMT) of B16F10 cells.The B16F10 cells, which is a malignant melanoma cell line widely used in research, irradiated by 12C6+ and X-ray were detected by Hoechst 33342/propidium iodide ...
Zhang LP +6 more
europepmc +3 more sources
Emodin inhibits the proliferation and migration of B16F10 cells and induces their apoptosis. [PDF]
Emodin, extracted from the rhizomes of various Chinese herbs, is a natural anthraquinone derivative with the formula C15H10O5. Many recent studies have shown that emodin has an antitumour effect. In this study, emodin was investigated in vitro to observe its effect on the proliferation, migration, and apoptosis of the B16F10 melanoma cell line.B16F10 ...
Yuan M +13 more
europepmc +4 more sources
Anti-Melanogenic Effects of L-Theanine on B16F10 Cells and Zebrafish. [PDF]
L-Theanine, a natural amino acid found in green tea (Camellia sinensis) leaves, is known for its diverse psychotropic effects. This study aimed to evaluate the inhibitory effect of L-theanine on melanin production and uncover its regulatory mechanism. We evaluated the anti-melanogenic activities of L-theanine in vitro and in vivo.
Yu CL, Pang H, Run Z, Wang GH.
europepmc +4 more sources
Effects of Resveratrol Derivatives on Melanogenesis and Antioxidant Activity in B16F10 Cells. [PDF]
Excessive melanogenesis causes abnormal pigmentation and a higher risk of skin disorders (e.g., melanoma). Resveratrol (RSV), a natural polyphenol, exerts antioxidant and anti-aging effects. However, the effects of RSV and its derivatives on melanogenesis remain unclear. This study investigated their effects on melanogenesis and antioxidant activity in
Kim S, Jhin C, Lee S, Rho HS, Park CY.
europepmc +3 more sources
Peptide Phe-Thr-Gly-Met-Leu (FTGML) is a bioactive oligopeptide with tyrosinase inhibitory activity derived from gelatin hydrolysate of grass carp scales.
Zizi Hu +4 more
doaj +3 more sources

