Inhibitory Effects of Cycloheterophyllin on Melanin Synthesis
This study was performed to clarify the inhibitory effects of cycloheterophyllin on melanin synthesis. In order to elucidate the inhibitory effects of cycloheterophyllin on the B16F10 cell line, cell viability, messenger ribonucleic acid (mRNA ...
Joong-Hyun Shim
doaj +1 more source
The axis IL-10/claudin-10 is implicated in the modulation of aggressiveness of melanoma cells by B-1 lymphocytes. [PDF]
B-1 lymphocytes are known to increase the metastatic potential of B16F10 melanoma cells via the extracellular signal-regulated kinase (ERK) pathway. Since IL-10 is associated with B-1 cells performance, we hypothesized that IL-10 could be implicated in ...
Elizabeth Cristina Perez +8 more
doaj +1 more source
Acenocoumarol, an Anticoagulant Drug, Prevents Melanogenesis in B16F10 Melanoma Cells
Hyperpigmentation can occur in abnormal skin conditions such as melanomas, as well as in conditions including melasma, freckles, age spots, seborrheic keratosis, and café-au-lait spots (flat brown spots). Thus, there is an increasing need for the development of depigmenting agents.
Hyunju Han, Changgu Hyun
openaire +3 more sources
Silencing of diphthamide synthesis 3 (Dph3) reduces metastasis of murine melanoma. [PDF]
Melanoma is the most dangerous skin cancer due to its highly metastatic potential and resistance to chemotherapy. Currently, there is no effective treatment for melanoma once it is progressed to metastatic stage. Therefore, further study to elucidate the
Lei Wang +7 more
doaj +1 more source
Evaluation of [99mTc][Tc-HYNIC/EDDA]-Tyr as a target for metabolic tumor imaging in B16F10 melanoma tumor [PDF]
Objective(s): Clinical interest in metabolic imaging of cancer has been growing in recent years. The increase in protein metabolism of cancer cells is interesting target for metabolic tumor imaging, for which radiolabeled amino acids can be applied.
Hemat Yaghoubi Mogadam +3 more
doaj +1 more source
Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models [PDF]
Melanomas are highly lethal skin tumours that are frequently treated by surgical resection. However, the efficacy of such procedures is often limited by tumour recurrence and metastasis. Caveolin-1 (CAV1) has been attributed roles as a tumour suppressor,
Aguilar-Guzmán, L +11 more
core +2 more sources
Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours [PDF]
Natural killer (NK) lymphocytes are part of the innate immune system and are important in immune protection against tumourigenesis. NK cells display a broad repertoire of activating and inhibitory cell surface receptors that regulate NK cell activity ...
Filtjens, Jessica +10 more
core +2 more sources
Investigation of microsphere-mediated cellular delivery by chemical, microscopic and gene expression analysis [PDF]
Amino functionalised cross-linked polystyrene microspheres of well defined sizes (0.2-2 mm) have been prepared and shown to be efficient and controllable delivery devices, capable of transporting anything from small dye molecules to bulky proteins into ...
Akhtar +50 more
core +1 more source
The effect of ciprofloxacin on the growth of B16F10 melanoma cells
Objective: The antitumor effect of ciprofloxacin has been widely assessed in-vitro , and positive results have been reported. The aim of this study was to investigate the influence of ciprofloxacin treatment on the growth of B16F10 melanoma cells
Dalal Fares, Jaber +2 more
openaire +2 more sources
A characterization of four B16 murine melanoma cell sublines molecular fingerprint and proliferation behavior [PDF]
Background: One of the most popular and versatile model of murine melanoma is by inoculating B16 cells in the syngeneic C57BL6J mouse strain. A characterization of different B16 modified cell sub-lines will be of real practical interest.
Barbu-Tudoran, Lucian +8 more
core +1 more source

