Results 101 to 110 of about 9,520,801 (360)
Human Vaccines & Immunotherapeutics, 2019 Opioid use disorders (OUD) and fatal overdoses are a national emergency in the United States. Therapeutic vaccines offer a promising strategy to treat OUD and reduce the incidence of overdose.
Christine Robinson +5 more
doaj +1 more source
Quantifying evolutionary constraints on B cell affinity maturation
, 2014 The antibody repertoire of each individual is continuously updated by the evolutionary process of B cell receptor mutation and selection. It has recently become possible to gain detailed information concerning this process through high-throughput ...
Bedford, Trevor +5 more
core +2 more sources
Tfg (Trk fused gene) is a Carma-1/IKKgamma interacting protein involved in CD40-induced canonical NF-KB signaling [PDF]
, 2009 Carma-1 is required for B cell receptor-/CD40- and T cell receptor-/CD28-induced B- and T-cell activation via JNK and NF-betaB. In B cells, Carma-1 becomes phosphorylated by PKCbeta, leading to its oligomerization.
Grohmann, Marcus +6 more
core +1 more source
Unique B cell responses in B cell-dependent and B cell-independent EAE
Autoimmunity, 2011 Previous studies characterized B cell-dependent and B cell-independent models of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice. To further characterize the B cell response generated in these two models, the serum antibody response and the B cell surface immunoglobulin (Ig) repertoire were analyzed following immunization of wild-type ...
Guorong, Liu +3 more
openaire +2 more sources
Cancer Management and Research, 2020 Ziyue Liu,1 Yuelun Zhang,2 Yicheng Zhu,1 Wei Zhang3 1Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 2Central Research ...
Liu Z, Zhang Y, Zhu Y, Zhang W
doaj
High fat diet deviates PtC-specific B1 B cell phagocytosis in obese mice [PDF]
, 2014 Phagocytosis had been attributed predominantly to "professional" phagocytes such as macrophages, which play critical roles in adipose tissue inflammation.
Allaimo, Danielle +8 more
core +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Effect of Cyclophosphamide on miRNA-15a expression in EBV infected transformed B cell
فصلنامه دانشگاه علوم پزشکی جهرم, 2021 Background: Despite advances in diagnosis and therapy of cancer, it is still the main cause of death worldwide. Cyclophosphamide is one of the major drugs for lymphoma treatment.
Abdolreza Sotoodeh Jahromi +4 more
doaj
Non-Hodgkin and Hodgkin Lymphomas Select for Overexpression of BCLW. [PDF]
, 2017 Purpose: B-cell lymphomas must acquire resistance to apoptosis during their development. We recently discovered BCLW, an antiapoptotic BCL2 family member thought only to contribute to spermatogenesis, was overexpressed in diffuse large B-cell lymphoma ...
Adams, Clare M. +3 more
core +1 more source