Results 161 to 170 of about 9,437,655 (307)

Identification of Epigenetic Alteration of the IFI44L Gene in B Cells of Sjogren’s Syndrome as a Clinical Biomarker and Molecular Significance

Journal of Inflammation Research
Kaiyuan Zhang,1,* Ziyue Luo,2,* Xinyi Yao,2 Dingqi Lu,2 Tao Hong,3 Xinchao Zhu,2 Mei Chen,2 Xinchang Wang4 1School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China ...
Zhang K, Luo Z, Yao X, Lu D, Hong T, Zhu X, Chen M, Wang X   +7 more
doaj  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, Volume 20, Issue 6, Page 1612-1625, June 2026.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Unique chicken B cell development: species-specific mechanisms and contradictory requirements of B cell receptor for post-hatched B cell development. [PDF]

Front Immunol
Woo SJ, Songodan T, Han JY.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

HIV causes global B cell dysregulation and restricts HBV-specific B cell development in an incident HBV cohort. [PDF]

J Clin Invest
Cascino KE, Liechti T, Seaberg EC, Stevens K, Wolinsky SM, Witt MD, Mailliard RB, Roederer M, Bailey JR, Thio CL, Cox AL.   +10 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Erythrocyte patch for enhanced B cell depletion therapy. [PDF]

Sci Adv
Liu J, Wang F, Li L.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

The multilayered identity of B cell memory. [PDF]

Cell Mol Immunol
Glaros V, Francis N, Kreslavsky T.
europepmc   +1 more source

PIT CELLS AS NATURAL KILLER CELLS

Biomedical Research, 1983
KANEDA, KENJI, DAN, CHIEKO, WAKE, KENJIRO   +2 more
openaire   +1 more source