Optimized CUT&RUN protocol for activated primary mouse B cells. [PDF]
Ruiz SE, Maul RW, Gearhart PJ.
europepmc +1 more source
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci+6 more
wiley +1 more source
B cells are not drivers of stromal cell activation during acute CNS infection. [PDF]
Boylan BT+6 more
europepmc +1 more source
Mild alkaline hydrolysis of lipopolysaccharide endotoxin enhances its mitogencity for murine B cells [PDF]
G W Goodman, Barnet M. Sultzer
openalex +1 more source
Landscape of BRAF transcript variants in human cancer
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda+5 more
wiley +1 more source
Cold-blooded vertebrates evolved regulatory B cells to participate in inflammatory diseases. [PDF]
Wang J+11 more
europepmc +1 more source
Accumulation of dopamine in mouse pancreatic B-cells following injection of L-DOPA. Localization to secretory granules and inhibition of insulin secretion [PDF]
Lars Ericson+2 more
openalex +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren+16 more
wiley +1 more source
MicroRNA-196a increases apoptosis in B cells through downregulation of FOXO1. [PDF]
Kim S+7 more
europepmc +1 more source
Cytotoxic effects of streptozotocin and N-nitrosomethylurea on the pancreatic B cells with special regard to the role of nicotinamide–adenine dinucleotide [PDF]
R Gunnarsson+2 more
openalex +1 more source