Results 121 to 130 of about 26,623 (217)

Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer's management. [PDF]

PLoS One
Ahmad I, Waheed S, Alotaibi BS, Abbasi SW, Khan MU, Rahman FU, Dib H, Fawy KF, Nishan U, Ali A, Zaman A, Shah M.   +11 more
europepmc   +1 more source

Nano-magnolol enhances the modulatory effects of magnolol on cognitive performance and BACE1-related biochemical changes in an STZ-induced rat model of Alzheimer's disease. [PDF]

Discov Nano
Youssef B, Ibrahim EA, Moselhy SS, ElShebiney S, ELabd WK.   +4 more
europepmc   +1 more source

lncRNAs: key player in Aβ deposition. [PDF]

RNA Biol
Wang RM, Wang ZQ.
europepmc   +1 more source

BACE1 in central nervous system myelination revisited [PDF]

Molecular Psychiatry, 2011
Treiber, H., Hagemeyer, N., Ehrenreich, H., Simons, M.   +3 more
openaire   +4 more sources

RNA-binding activity of PHGDH drives amyloid-beta production in a human brain organoid model of sporadic Alzheimer's disease. [PDF]

Proc Natl Acad Sci U S A
Chen J, Xu M, Liu Y, Hadi F, Xue S, Chien S, Zhong S.   +6 more
europepmc   +1 more source

Identifying Potential BACE1 Inhibitors from the ChEMBL Database Using Machine Learning and Atomistic Simulation Approaches. [PDF]

ACS Omega
Dao QT, Do TMD, Thai QM, Tran PT, Ngo ST, Nguyen TH.   +5 more
europepmc   +1 more source

Design, validation, and functional impact of oligonucleotides for multigene silencing in Alzheimer's disease. [PDF]

Mol Ther Nucleic Acids
Woffindale C, Riera NG, Wood MJA, Varela MA.   +3 more
europepmc   +1 more source

Computational prioritization of multi-target inhibitors: explainable QSAR and docking-based discovery of dual AChE/BACE1 chemotypes. [PDF]

J Comput Aided Mol Des
Bozkır İ, İbişoğlu MS, Kayıkçıoğlu Bozkır İ, Güler Hİ.   +3 more
europepmc   +1 more source

Discontinued BACE1 Inhibitors in Phase II/III Clinical Trials and AM-6494 (Preclinical) Towards Alzheimer's Disease Therapy: Repurposing Through Network Pharmacology and Molecular Docking Approach. [PDF]

Pharmaceuticals (Basel)
Ugbaja SC, Kumalo HM, Gqaleni N.
europepmc   +1 more source

Ramalin Ameliorates Alzheimer's Disease Pathology by Targeting BACE1, HDAC6, and MAPK Pathways. [PDF]

MedComm (2020)
Cho Y, Lee J, Choi BY, Yun JH, Han S, Baek SH, Park J, Cho Y, Kim HK, Kim E, Palomera LF, Lim J, Jeon Y, Im J, Hong JM, Kim TK, Kim SH, Yim JH, Jo DG.   +18 more
europepmc   +1 more source