Results 101 to 110 of about 36,341 (274)

Complementary Sensory and Associative Microcircuitry in Primary Olfactory Cortex [PDF]

open access: yes, 2011
The three-layered primary olfactory (piriform) cortex is the largest component of the olfactory cortex. Sensory and intracortical inputs converge on principal cells in the anterior piriform cortex (aPC).Wecharacterize organization principles of the ...
Beed, Prateep   +5 more
core   +2 more sources

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Untersuchung neuroprotektiver Effekte der intrathekalen Baclofenapplikation [PDF]

open access: yes, 2006
Cerebral-ischämische Erkrankungen nehmen eine wichtige Rolle bei der Versorgung neurologischer und neurochirurgischer Patienten ein. Sie sind darüberhinaus ein enormer gesundheitsökonomischer Faktor.
Becker, Ralf (Dr.), Ludolph, Alexander
core   +1 more source

Effectiveness and safety of abobotulinumtoxinA in pediatric lower limb spasticity: A phase IV, prospective, observational, multicenter study

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To assess the longitudinal attainment of patient‐centered, function‐related Goal Attainment Scaling Total (GAS T)‐score after repeated abobotulinumtoxinA (AboBoNT‐A) injections over a period of up to 30 months and up to 10 cycles. Method In this prospective observational study, the investigators' clinical practices recruited patients aged ...
Mark E. Gormley   +7 more
wiley   +1 more source

A randomized, open-label, standard controlled, parallel group study of efficacy and safety of baclofen, and chlordiazepoxide in uncomplicated alcohol withdrawal syndrome

open access: yesBiomedical Journal, 2016
Background: Alcohol withdrawal syndrome (AWS) is a distressing condition, generally controlled by benzodiazepines (BZD's). Baclofen, a gamma-aminobutyric acid-B (GABAB) agonist, has also shown promising results in controlling AWS.
K. Girish   +8 more
doaj   +1 more source

Improving GHB withdrawal with baclofen [PDF]

open access: gold, 2021
National Institute for Health Research
openalex   +1 more source

Outcomes of selective dorsal rhizotomy in ambulatory children and young people with cerebral palsy: A scoping review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This scoping review highlights that in the selective dorsal rhizotomy (SDR) literature, the emphasis still remains on impairment‐based outcomes in the body function and structure domain of the ICF. However, there has been a small shift towards participation and quality‐of‐life outcomes in the last decade.
Deepti Chugh   +7 more
wiley   +1 more source

GABA\u3csub\u3eB\u3c/sub\u3e Receptors Couple to Gα\u3csub\u3eq\u3c/sub\u3e to Mediate Increases in Voltage-Dependent Calcium Current During Development [PDF]

open access: yes, 2015
Metabotropic GABAB receptors are known to modulate the activity of voltage-dependent calcium channels. Previously, we have shown that GABAB receptors couple to a non-Gi/o G-protein to enhance calcium influx through L-type calcium channels by activating ...
Karls, Andrew S., Mynlieff, Michelle
core   +1 more source

The Possibility of Using Different Variants HPLC in Determining Baclofen in Biological Objects [PDF]

open access: yes, 2015
Рассмотрены возможности определения баклофена в биологических жидкостях (крови, моче) методом ВЭЖХ с различными вариантами детектирования с целью подтверждения диагноза отравление баклофеном. Для идентификации и количественного определения баклофена в
Dukova, Olga A.   +9 more
core   +1 more source

Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale

open access: yesGeriatrics &Gerontology International, EarlyView.
ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi   +4 more
wiley   +1 more source

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