Baclofen Withdrawal–Induced Psychosis in the Setting of Renal Insufficiency
Journal of Investigative Medicine High Impact Case Reports, 2022 Baclofen is used to treat muscle spasticity, acting at GABA B receptors in the central nervous system. The abrupt cessation of baclofen causes baclofen withdrawal–induced psychosis. The risk is exacerbated if the patient has renal insufficiency or if the
Guilmette Amanda +4 more
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Correlates of baclofen effectiveness in alcohol dependence
Indian Journal of Psychological Medicine, 2015 Alcohol dependence is a global concern. Baclofen has shown promise as an anti-craving agent but its efficiency remains to be settled. We reviewed 549 male cases diagnosed with alcohol dependence who received Acamprosate (201) or Baclofen (348).
Lekhansh Shukla +6 more
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Presynaptic actions of 4-Aminopyridine and γ-aminobutyric acid on rat sympathetic ganglia in vitro [PDF]
, 1980 Responses to bath-applications of 4-aminopyridine (4-AP) and -aminobutyric acid (GABA) were recorded intracellularly from neurones in the rat isolated superior cervical ganglion.
A Nistri +36 more
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GABA increases electrical excitability in a subset of human unmyelinated peripheral axons [PDF]
, 2010 A proportion of small diameter primary sensory neurones innervating human skin are chemosensitive. They respond in a receptor dependent manner to chemical mediators of inflammation as well as naturally occurring algogens, thermogens and pruritogens.
Carr, Richard W +3 more
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A population of immature cerebellar parallel fibre synapses are insensitive to adenosine but are inhibited by hypoxia [PDF]
, 2011 The purine adenosine plays an important role in a number of physiological and pathological processes and is neuroprotective during hypoxia and ischemia.
Atterbury, Alison, Wall, Mark J.
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The Effect of Ginkgo on Baclofen Induced Amnesia using Passive Avoidance Learning and Memory in Rats [PDF]
Journal of Fasa University of Medical Sciences, 2015 Background & Objective: Ginkgo biloba is an herbal medicine that has a positive effect on improving memory. It prevents oxidative damage in mitochondria and cell death in a variety of Neuropathies.
Elaheh Nooshinfar +3 more
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Bidirectional enantioselective effects of the GABAB receptor agonist baclofen in two mouse models of excessive ethanol consumption [PDF]
, 2015 The GABAB receptor agonist baclofen has been studied extensively in preclinical models of alcohol-use disorders, yet results on its efficacy have been uncertain.
Blasingame, Shelby N. +2 more
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O baclofeno intratecal no tratamento da espasticidade.
Acta Médica Portuguesa, 2006 The neuromotor techniques do not have good results in severe spasticity prevention and treatment (Ashworth Scale > or = 3). High doses of oral Baclofen are required, thus intrathecal baclofen is a current alternative.To assess the effectiveness of ...
Iolanda Veiros +2 more
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Solubility of baclofen in 1-hexyl-4-methylpyridinium bromide + water binary mixtures [PDF]
شیمی کاربردی روز, 2017 In this paper, solubility of baclofen was studied by gravimetric method. The solubility of baclofen was measured in (water + 1-hexyl-4-methylpyridinium bromide) binary mixtures from 293.1 K to 313.1 K under atmosphere pressure.
Abbas Mehrdad +2 more
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Current Perspective on the Location and Function of Gamma- Aminobutyric Acid (GABA) and its Metabolic Partners in the Kidney. [PDF]
, 2014 Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter located in the mammalian central nervous system, which binds to GABAA and GABAB receptors to mediate its neurological effects.
Dunn, Kadeshia +3 more
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