Results 41 to 50 of about 36,341 (274)

Intra-nucleus accumbens shell injections of R(+)- and S(-)-baclofen bidirectionally alter binge-like ethanol, but not saccharin, intake in C57Bl/6J mice [PDF]

, 2014
The GABAB agonist baclofen has been widely researched clinically and preclinically as a treatment of alcohol use disorders (AUDs). However, the efficacy of baclofen remains uncertain.
Boehm II, Stephen L., Kasten, Chelsea R.
core   +1 more source

Baclofen overdose presenting as psychosis with catatonia

Indian Journal of Psychological Medicine, 2017
Baclofen is a centrally acting gamma-aminobutyric acid receptor agonist with many therapeutic uses in neurology and psychiatry. An overdose of baclofen is known to cause serious side effects such as encephalopathy, seizures, respiratory depression, and ...
Abhinav Nahar, Mukku Shiva Shanker Reddy, Bhaskaran Andi Subramaniyam, Harish Thippeswamy, Prabha S Chandra, Santosh Kumar Chaturvedi   +5 more
doaj   +1 more source

Overtime Histological Changes in the Lungs after Intoxication with Baclofen Alone or in Combination with Ethanol (Experimental Study)

Общая реаниматология, 2023
The aim of the study was to evaluate the overtime histological changes in the lungs after intoxication with baclofen alone or in combination with ethanol.Materials and methods.
O. L. Romanova, M. L. Blagonravov, P. G. Dzhuvalyakov, V. I. Torshin, A. V. Ershov, E. Kh. Barinov   +5 more
doaj   +1 more source

How to Manage Self-Poisoning With Baclofen in Alcohol Use Disorder? Current Updates

Frontiers in Psychiatry, 2018
Specialists in addiction medicine continue to debate whether baclofen is still indicated to treat alcohol use disorders in view of conflicting results as to its efficacy.
Nicolas Franchitto, Nicolas Franchitto, Nicolas Franchitto, Benjamin Rolland, Benjamin Rolland, Fanny Pelissier, Nicolas Simon   +6 more
doaj   +1 more source

Effects of the GABA(B) agonist baclofen on volitional swallowing in normal subjects

Kaohsiung Journal of Medical Sciences, 2023
The GABA(B) receptor agonist baclofen is known to suppress the rate of spontaneous swallowing but not pharyngeal muscle contraction. The extent to which baclofen may alter volitional swallowing is not currently known.
Jui‐Sheng Hung, Shu‐Wei Liang, Taher Omari, Ming‐Wun Wong, Wei‐Yi Lei, Chih‐Hsun Yi, Tso‐Tsai Liu, Lin Lin, Chien‐Lin Chen   +8 more
doaj   +1 more source

Beneficial effects of childhood selective dorsal rhizotomy in adulthood [PDF]

, 2017
Background: Selective dorsal rhizotomy (SDR) has been used to treat children with spastic cerebral palsy (CP) for over three decades. However, little is known about the outcomes of childhood SDR in adults.
Dobbs, Matthew B, Edwards, Caleb, Liu, Jenny L, Park, T. S, Walter, Deanna M   +4 more
core   +2 more sources

The Mammalian Interaural Time Difference Detection Circuit Is Differentially Controlled by GABAB Receptors during Development [PDF]

, 2010
Throughout development GABAB receptors (GABABRs) are widely expressed in the mammalian brain. In mature auditory brainstem neurons, GABABRs are involved in the short-term regulation of the strength and dynamics of excitatory and inhibitory inputs, thus ...
Grothe, Benedikt, Hassfurth, Benjamin, Koch, Ursula   +2 more
core   +1 more source

An unusual case of baclofen abuse

Indian Journal of Psychological Medicine, 2016
Baclofen was initially used for the treatment of spastic conditions. Last decade has seen its emergence as a treatment of profound interest in alcohol dependence, opiates and cocaine abuse, and tobacco addiction.
Soumitra Das, Dhanya Sasidharan Palappalllil, Sumesh Thoppil Purushothaman, Varun Rajan   +3 more
doaj   +1 more source

Clinical Practice Guideline for Evaluation and Management of Peripheral Nervous System Manifestations in Sjögren's Disease

Arthritis Care &Research, Accepted Article.
Objectives Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies. To help patients and providers in the decision‐making process, we developed
Anahita Deboo, Robert Fox, Katherine M. Hammitt, Julie Frantsve‐Hawley, Matthew C. Baker, Stamatina Danielides, Eduardo De Sousa, Brent P. Goodman, Jennifer K. King, Steven Mandel, Ghaith Noaiseh, Pantelis P. Pavlakis, George Sarka, R. Hal Scofield, Arun Varadhachary, Daniel J. Wallace, Matt Makara, Nancy Carteron, Steven Carsons, In collaboration with the Consensus Expert Panel (CEP) members   +19 more
wiley   +1 more source

Baclofen-Induced Coma Reversible by Dialysis in a Patient Affected by Acute Kidney Injury

Clinical Management Issues, 2022
Baclofen is commonly used to treat muscular spasticity and other conditions such as pain, alcohol withdrawal, and myoclonus. It is contraindicated in chronic kidney disease.
Oliver Malle, Tadeja Urbanic Purkart, Karin Amrein   +2 more
doaj   +1 more source