Suppression of alcohol-dependence using baclofen: a two-year observational study of 100 patients.
Frontiers in Psychiatry, 2012 Aims: The purpose of this study was to examine the long-term effects of baclofen in a large cohort of alcohol-dependent patients compliant to baclofen treatment.
Renaud eDe Beaurepaire
doaj +1 more source
GABA_{B} Receptors Regulate Chick Retinal Calcium Waves [PDF]
, 2001 Correlated spiking activity and associated Ca²⁺ waves in the developing retina are important in determining the connectivity of the visual system. Here, we show that GABA, via GABA_{B} receptors, regulates the temporal characteristics of Ca²⁺ waves ...
Catsicas, M, Mobbs, P
core
The Mammalian Interaural Time Difference Detection Circuit Is Differentially Controlled by GABAB Receptors during Development [PDF]
, 2010 Throughout development GABAB receptors (GABABRs) are widely expressed in the mammalian brain. In mature auditory brainstem neurons, GABABRs are involved in the short-term regulation of the strength and dynamics of excitatory and inhibitory inputs, thus ...
Grothe, Benedikt +2 more
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Evaluation of an innovative, green, and eco-friendly baclofen-loaded niosome (Baclosome) formulation for pain management by transdermal delivery [PDF]
Nanomedicine JournalObjective(s): Baclofen, a muscle relaxant, exhibits limited dermal penetration, restricting its therapeutic efficacy. This study aimed to optimize baclofen delivery using ultrasonically manufactured niosomes (Baclosomes) for improved antinociceptive and ...
Jafar Akbari +5 more
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Movement Disorders in Neuromyelitis Optica Spectrum Disorder: A Systematic Review
Movement Disorders Clinical Practice, EarlyView.Abstract Background Several movement disorders (MD) have been reported to occur in neuromyelitis optica spectrum disorder (NMOSD). No extensive review has addressed the whole spectrum of MD in NMOSD. Objective This article aims to review MD in NMOSD, describing its prevalence and features.
Luciana A.F. Bringel +18 more
wiley +1 more source
Baclofen-Induced Coma Reversible by Dialysis in a Patient Affected by Acute Kidney Injury
Clinical Management Issues, 2022 Baclofen is commonly used to treat muscular spasticity and other conditions such as pain, alcohol withdrawal, and myoclonus. It is contraindicated in chronic kidney disease.
Oliver Malle +2 more
doaj +1 more source
Managing Dystonia in Partington Syndrome
Movement Disorders Clinical Practice, EarlyView.Abstract Background Bilateral focal hand dystonia is an almost pathognomonic sign of Partington syndrome, frequently accompanied by intellectual disability and oromotor dyspraxia. However, a few studies have focused on the treatment of this focal dystonia, making patient management uncertain.
Emilie Pichon +13 more
wiley +1 more source
Journal of Ovarian Research, 2020 Objective This study aimed to explore the effects of activating GABAB1 receptor by baclofen on proliferation, migration, invasion and epithelial-mesenchymal transition (EMT) of ovarian cancer cells.
Jun Gao +7 more
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Management of Central Hyperthermia in Traumatic Brain Injury Using Baclofen
Indian Journal of Physical Medicine & Rehabilitation, 2023 Central hyperthermia in cases of traumatic brain injury (TBI) is often misdiagnosed or underdiagnosed due to inadequate data. The current diagnosis is one of exclusion. Existing treatment as per guidelines is symptomatic and supportive.
Ijaz N. Pillai, Gaurav Gomez
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New Aspects of Thromboangiitis obliterans (von Winiwarter-Buerger's Disease) [PDF]
, 1984 The existence of thromboangiitis obliterans as a clinical entity has been a matter of debate for many years. In contrast to other immunovasculitides there is no organ involvement while peripheral vessels are affected.
Berlit, Peter +3 more
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