Results 81 to 90 of about 36,785 (263)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

A hopeful therapy for Niemann-Pick C diseases [PDF]

, 2017
Not abstract ...
Erickson, Robert P., Fiorenza, Maria Teresa   +1 more
core   +1 more source

Early Onset Dystonia, Parkinsonism, and Spasticity in Siblings with VAC14‐Associated Neurodegeneration: A Case Report and Literature Review

Movement Disorders Clinical Practice, EarlyView.
Rebecca Lindsay, Sangeetha Yoganathan, Wei Kang Lim, Pradeep Krishnan, Asif Doja, Sunita Venkateswaran, Julie Richer, Sara Breitbart, Nicole S.Y. Liang, Alfonso Fasano, George M. Ibrahim, Carolina Gorodetsky   +11 more
wiley   +1 more source

Neurobiologische Korrelate der Belohnungs- und Suchtreizverarbeitung im Rahmen der Alkoholabhängigkeit und deren pharmakologische Modifikation mit Baclofen [PDF]

, 2020
Hintergrund: In der Erforschung alkoholbezogener psychischer Störungen konnte festgestellt werden, dass eine veränderte neurobiologische Verarbeitung des mesokortikolimbischen dopaminergen Systems, des sogenannten Belohnungssystems, vorliegt.
Pelz, Patricia
core   +1 more source

Effects of baclofen on insular gain anticipation in alcohol-dependent patients — a randomized, placebo-controlled, pharmaco-fMRI pilot trial [PDF]

, 2022
Patricia Pelz, Alexander Genauck, Robert C. Lorenz, Torsten Wüstenberg, Carolin Wackerhagen, Katrin Charlet, Tobias Gleich, Olga Geisel, Andreas Heinz, Christian Müller, Anne Beck   +10 more
openalex   +1 more source

A rare case report of baclofen induced mania: Uncovering the unexpected

Telangana Journal of Psychiatry
Baclofen is one of the most commonly used anti-craving agents; the effect is mainly mediated by antagonizing GABA-B receptors, thereby reducing the craving for alcohol.
Barath Ramanathan, Souganya Vijayan, Arun Selvaraj, Mirdula Devi   +3 more
doaj   +1 more source

Symptomatic treatment of children with anti-NMDAR encephalitis. [PDF]

, 2016
AIM: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Brilot, F, Dale, R. C., Hong, M, Jones, H, Mohammad, Ss, Nosadini, M, Pillai, Sc, Sharpe, C   +7 more
core   +1 more source

Neurological evolution of severe baclofen intoxication: from brain death mimic to recovered brain function [PDF]

, 2023
Sebastian Berger, Tobias Kuster, Raoul Sutter, Urs Fisch   +3 more
openalex   +1 more source

How copy number variations shape brain developmental disorders: Unraveling the synaptic puzzle

Psychiatry and Clinical Neurosciences, EarlyView.
Neurodevelopmental disorders (NDDs), such as schizophrenia (SCZ), Attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), learning disabilities, and intellectual disabilities (ID), are highly prevalent. One significant genetic factor associated with NDDs is copy number variations (CNVs), which are structural changes in the ...
Tianqi Wang, Kubra Trabzonlu, Emily Fullard Jones, Yasir Ahmed Syed   +3 more
wiley   +1 more source

Severe, Protracted Spasm of Urinary Bladder and Autonomic Dysreflexia Caused by Changing the Suprapubic Catheter in a Cervical Spinal Cord Injury Patient: Treatment by a Bolus Dose and Increased Total Daily Dose of Intrathecal Baclofen

Clinical Medicine Insights: Case Reports, 2016
Background Intrathecal administration of baclofen by implanted pump reduces rigidity and muscle spasms. Its use specifically to control bladder spasms has not been reported.
Subramanian Vaidyanathan, Tun Oo, Bakul M. Soni, Peter L. Hughes, Gurpreet Singh   +4 more
doaj   +1 more source