Results 51 to 60 of about 1,943,316 (288)
mBio, 2020 The type VI secretion system (T6SS) is a critical weapon in bacterial warfare between Gram-negative bacteria. Although invaluable for niche establishment, this machine represents an energetic burden to its host bacterium.
Juvenal Lopez +2 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Microbiology SpectrumEnterohemorrhagic Escherichia coli (EHEC) is notable for the Shiga-like toxin and several secretion systems and virulence factors that facilitate intestinal colonization and pathogenesis.
Jaime Vazquez-Lopez +5 more
doaj +1 more source
Competition in evolving communications markets: issues paper [PDF]
, 2016 The Australian Competition and Consumer Commission (ACCC) has commenced a market study to examine a range of interrelated matters that have been raised by the industry that may affect the development of competition and efficiency in communications ...
Australian Competition and Consumer Commission
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Role of competition for substrate in bacterial antagonism in the gut [PDF]
Infection and Immunity, 1982 Small slices of agar, each containing about 10(5.5) Escherichia coli organisms, were preincubated either in the contents of rat cecum or in brain heart infusion broth for 2 h and then were transferred to a small sample of saline. The purpose of these experiments was to examine the ability of E.
openaire +2 more sources
Leveraging strain competition to address antimicrobial resistance with microbiota therapies
Gut MicrobesThe enteric microbiota is an established reservoir for multidrug-resistant organisms that present urgent clinical and public health threats. Observational data and small interventional studies suggest that microbiome interventions, such as fecal ...
Danielle Barrios Steed +5 more
doaj +1 more source
Bacteria-Killing Type IV Secretion Systems
Frontiers in Microbiology, 2019 Bacteria have been constantly competing for nutrients and space for billions of years. During this time, they have evolved many different molecular mechanisms by which to secrete proteinaceous effectors in order to manipulate and often kill rival ...
Germán G. Sgro +10 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source