Results 81 to 90 of about 2,038,554 (284)

In silico Analyses of Core Proteins and Putative Effector and Immunity Proteins for T6SS in Enterohemorrhagic E. coli

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Shiga-toxin-producing Escherichia coli (STEC) has become an important pathogen that can cause diarrhea, hemorrhagic colitis and hemolytic uremic syndrome (HUS) in humans.
Jaime Vazquez-Lopez   +1 more
doaj   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analysis of the Type VI secretion system and microbiological characteristics of hypervirulent Klebsiella pneumoniae causing urinary tract infections

open access: yesJournal of Infection in Developing Countries
Introduction: This study aimed to evaluate the Type VI secretion system (T6SS) and microbiological features in hypervirulent Klebsiella pneumoniae (hvKP) causing urinary tract infections (UTIs) in hospitalized adults.
Fei-Fei Li   +4 more
doaj   +3 more sources

Handbook of Belgian Competition Law. Anticompetitive practices

open access: yes, 2021
Le Manuel de droit belge de la concurrence présente le droit belge des pratiques restrictives de concurrence : • le Chapitre I porte sur le droit des ententes entre entreprises : cartels, accords de coopération horizontale et accords verticaux ; • le ...
Neyrinck, Norman
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

THE EVOLUTION OF RESTRAINT IN BACTERIAL BIOFILMS UNDER NONTRANSITIVE COMPETITION [PDF]

open access: yesEvolution, 2008
Theoretical and empirical evidence indicates that competing species can coexist if dispersal, migration, and competitive interactions occur over relatively small spatial scales. In particular, spatial structure appears to be critical to certain communities with nontransitive competition.
Federico, Prado, Benjamin, Kerr
openaire   +2 more sources

Interbacterial warfare in the human gut: insights from Bacteroidales’ perspective

open access: yesGut Microbes
Competition and cooperation are fundamental to the stability and evolution of ecological communities. The human gut microbiota, a dense and complex microbial ecosystem, plays a critical role in the host’s health and disease, with competitive interactions
Kun Jiang   +6 more
doaj   +1 more source

Baseplate Component TssK and Spatio-Temporal Assembly of T6SS in Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology, 2019
The Gram-negative bacteria use the contractile multi-molecular structure, called the Type VI Secretion System (T6SS) to inject toxic products into eukaryotic and prokaryotic cells.
David Liebl   +5 more
doaj   +1 more source

Exploring the ordoliberal paradigm : the competition-democracy nexus [PDF]

open access: yes, 2016
The present article purports to shed a new light on ordoliberalism and to explore its role in EU competition law. For this purpose, the article analyses the ordoliberal school of thought in its historical context and re-conceptualizes its understanding ...
DEUTSCHER, Elias, MAKRIS, Stavros
core  

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