Results 51 to 60 of about 32,024 (272)
The effect of nanoparticle size on the probability to cross the blood-brain barrier: an in-vitro endothelial cell model [PDF]
, 2015 BACKGROUND: During the last decade nanoparticles have gained attention as promising drug delivery agents that can transport through the blood brain barrier.
Anat Sharon +5 more
core +1 more source
Abuse of gabapentinoids in individuals with substance use disorders
Journal of Forensic Sciences, EarlyView.Abstract The abuse of gabapentinoids has increased rapidly, and death cases have been reported with increasing rates. This study examines the toxicological analysis data of substance abuse cases conducted after legal regulations were implemented in Türkiye.
İnci Sağlam +3 more
wiley +1 more source
Identification of Barbiturates [PDF]
Nature, 1959 IN Great Britain the most common poisons at the present time are the 5 : 5′ disubstituted barbiturates. The longer-acting barbiturates, barbitone and phenobarbitone, can accumulate in the body when administered in relatively low therapeutic dosage, and concentrations of these drugs in the blood of about 5 mgm./100 ml. do not necessarily imply poisoning.
openaire +3 more sources
Central nervous system depressant effect of the fruits of Piper guineense [PDF]
, 2020 The central nervous system depressant effect of the butanol extract of the fruits of Piper guineense was pharmacologically screened by measuring the prolongation of barbiturate sleeping time. Nine rats (n=9) were used and assigned into three groups, with
Adedeji, Olusegun S. +3 more
core +2 more sources
Quantitative burst suppression on serial intermittent EEG in refractory status epilepticus
Clinical Neurophysiology Practice, 2021 Objectives: In refractory status epilepticus (RSE), the optimal degree of suppression (EEG burst suppression or merely suppressing seizures) remains unknown.
Joseph Peedicail +4 more
doaj
Addiction, EarlyView.Abstract Background and Aim Sedative, hypnotic or anxiolytic use disorders (SHA‐UD) are defined by significant impairment or distress caused by recurrent sedative, hypnotic or anxiolytic use. This study aimed to measure trends in the prevalence of SHA‐UD diagnoses in adolescent and young adult US Medicaid enrollees from 2001 to 2019.
Greta Bushnell +6 more
wiley +1 more source
State-Dependent Modulation of Slow Wave Motifs towards Awakening
Frontiers in Cellular Neuroscience, 2017 Slow cortical waves that propagate across the cerebral cortex forming large-scale spatiotemporal propagation patterns are a hallmark of non-REM sleep and anesthesia, but also occur during resting wakefulness.
Thomas Knöpfel +6 more
doaj +1 more source
Connections of the Mesencephalic Locomotor Region (MLR) in the Cat [PDF]
, 1980 The cat entopeduncular nucleus (EN), which is the main output of the basal ganglia, is known to project to the mesencephalic tegmentum. We have been able to elicit antidromic responses in single EN neurons from the region of the mesencephalic locomotor ...
Garcia-Rill, E. +2 more
core +2 more sources
3d/4f Coordination clusters as cooperative catalysts for highly diastereoselective Michael addition reactions [PDF]
, 2017 Michael addition (MA) is one of the most well studied chemical transformation in synthetic chemistry. Here, we re-port the synthesis and crystal structures of a library of 3d/4f coordination clusters (CCs) formulated as ZnII2YIII2L4(solv)X(Z)Y and study ...
Abdul-Sada, Alaa +8 more
core +3 more sources
Elevated rate of suicide risk in individuals with opioid use disorder
The American Journal on Addictions, EarlyView.Abstract Background and Objectives Few studies have longitudinally investigated suicide risk (SR) in opioid use disorder (OUD). This investigation administered three screening tools to individuals with OUD to compare rates of and variables associated with SR over 12 months.
Max Spaderna +19 more
wiley +1 more source