Results 91 to 100 of about 4,580,472 (190)

Precision multiplexed base editing in human cells using Cas12a-derived base editors

Nature Communications
Base editors enable the direct conversion of target nucleotides without introducing DNA double strand breaks, making them a powerful tool for creating point mutations in a human genome. However, current Cas9-derived base editing technologies have limited
Anabel Y. Schweitzer, Etowah W. Adams, Michael T. A. Nguyen, Monkol Lek, Farren J. Isaacs   +4 more
doaj   +1 more source

Investigations into the Cellular Mechanism of Base Editing [PDF]

, 2019
Base editing is a recent development in the genome editing field that allows for the introduction of single nucleotide changes in the genome with high efficiency.
Burnett, Cameron Andrew
core   +1 more source

Optimization of base editing tools in maize

, 2021
[ES] Las mutaciones puntuales dirigidas a través de técnicas de edición del genoma tienen un gran potencial para desarrollar variedades mejoradas de cultivos, ya que muchos rasgos agronómicos están determinados por polimorfismos de un solo nucleótido ...
González Campo, Camila
core  

Targeted RNA base editing for therapeutic: mechanisms and advances

Pharmaceutical Science Advances
RNA base editing, which enables RNA base modification through effector proteins guided by targeting systems, is a powerful technology to correct disease-associated point mutations.
Weikai Yan, Xiaocheng Weng
doaj   +1 more source

Lecture capture - editing recordings

, 2012
A shortened version of a JISC Legal video which offers practical advice for people who are preparing to record a lecture. This clip offers advice on basic editing tips for creating simple broadcasts and more complex ones. (with thanks to JISC Legal)
Jisc Legal
core  

Cytosine base editor-DNA binding domain fusions for editing window modulation in the RNP format

BMC Biotechnology
Summary Base editing technologies allow for the precise and efficient installation of defined nucleotide substitutions into a target genome without the introduction of double strand breaks or DNA templates.
Erin Brettmann, Fuqiang Chen, Stephen Beishir, Graeme Garvey   +3 more
doaj   +1 more source

Soil alkalinity and cotton production: Challenges, physiological effects, and sustainable solutions

Plant Stress
Alkali stress, marked by high soil pH (>8.5) and excess sodium bicarbonate/carbonate, threatens global cotton productivity, especially in arid regions.
Atif Raja, Zhang Bo, Noor Muhammad, Irfan Ullah Khan, Mubashir Abbas, Azhar Iqbal, Dong Qiang, Pu Yuanchun, Cao Fei, Zhang Xiaolei, Peng Hao, Qi Xiu, Gu Yunqi, Palizhati Yusufu, Asif Iqbal, Meizhen Song   +15 more
doaj   +1 more source

Principles and Significance of Base Editing and Prime Editing.

, 2021
Collected by Alex Sobko. No abstract available.
openaire   +2 more sources

Fast Vertex Merging for Cluster Editing

, 2021
FPT algorithms for cluster editing are relatively successful in practice, however there is still the need for a fast weighted graph data-structure that allows merging vertices and deleting edges while keeping track of a lower bound.
Holten, Lucas (author)
core  

Establishment of an Efficient Protoplast-Based Base Editing Platform in Lettuce

Agronomy
Lettuce (Lactuca sativa L.) is an important leafy vegetable crop, yet the efficiency and reliability of genome editing platforms in lettuce remain limited, particularly for precision base editing applications.
Yu Jia, Guo Peng, Qiang Zhou
doaj   +1 more source