The Acinar Cage: Basement Membranes Determine Molecule Exchange and Mechanical Stability of Human Breast Cell Acini. [PDF]
The biophysical properties of the basement membrane that surrounds human breast glands are poorly understood, but are thought to be decisive for normal organ function and malignancy.
Aljona Gaiko-Shcherbak +5 more
doaj +4 more sources
Ubiquitous supportive tissue adjacent to epithelium and around smooth and striated muscle cells. This tissue contains intrinsic macromolecular components such as collagen, laminin, and sulfated proteoglycans.
J. Ireland
openaire +2 more sources
Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries. [PDF]
The labyrinth is the highly vascularized part of the rodent placenta that allows efficient transfer of gases, nutrients, wastes, and other molecules between the maternal and embryonic circulations. These two blood compartments are separated by blastocyst-
Sung Tae Kim +3 more
doaj +12 more sources
Basement membrane perforations guide anterior–posterior axis formation [PDF]
Establishment of the anterior-posterior (AP) axis is a critical symmetry-breaking event in mammalian development. In mice, this process involves the directed migration of the distal visceral endoderm (DVE).
Dong-Yuan Chen +9 more
doaj +2 more sources
Basement membrane and stroke [PDF]
Located at the interface of the circulation system and the CNS, the basement membrane (BM) is well positioned to regulate blood–brain barrier (BBB) integrity. Given the important roles of BBB in the development and progression of various neurological disorders, the BM has been hypothesized to contribute to the pathogenesis of these diseases.
Yao Yao
openaire +3 more sources
Expression of basement membrane laminin in oral squamous cell carcinomas
Summary: The basement membrane is a dynamic structure that undergoes quantitative and qualitative changes during the progression of squamous cell carcinoma, which is essencially important in tumoral invasion and metastasis.
Silvia Regina de Almeida Reis +4 more
doaj +2 more sources
Beyond classical collagen: basement membrane collagen IV in age-associated lung diseases [PDF]
Chronic lung diseases such as COPD, asthma, idiopathic pulmonary fibrosis (IPF) and pulmonary hypertension are characterised by aberrant remodelling and degradation of the extracellular matrix.
Natalia El-Merhie +3 more
doaj +2 more sources
Vascular Basement Membrane Fragmentation in Keloids and the Expression of Key Basement Membrane Component Genes [PDF]
Background:. Keloids are growing scars that arise from injury to the reticular dermis and subsequent chronic local inflammation. The latter may be promoted by vascular hyperpermeability, which permits the ingress of chronic inflammatory cells/factors ...
Yusaku Saijo, MD +3 more
doaj +2 more sources
To form and function: on the role of basement membrane mechanics in tissue development, homeostasis and disease [PDF]
The basement membrane (BM) is a special type of extracellular matrix that lines the basal side of epithelial and endothelial tissues. Functionally, the BM is important for providing physical and biochemical cues to the overlying cells, sculpting the ...
Nargess Khalilgharibi, Yanlan Mao
doaj +1 more source
SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the blood–brain barrier (BBB).
Ling Zhang +20 more
semanticscholar +1 more source

