Results 21 to 30 of about 2,279,736 (377)

Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane

open access: yesCells, 2023
A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into ...
Shayan S. Nazari   +3 more
doaj   +1 more source

Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report

open access: yesSAGE Open Medical Case Reports, 2023
Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh   +3 more
doaj   +1 more source

Mechanisms of Basement Membrane Micro-Perforation during Cancer Cell Invasion into a 3D Collagen Gel

open access: yesGels, 2022
Cancer invasion through basement membranes represents the initial step of tumor dissemination and metastasis. However, little is known about how human cancer cells breach basement membranes.
Shayan S. Nazari   +2 more
doaj   +1 more source

The prognostic significance of type IV collagen expression in colorectal carcinomas [PDF]

open access: yesArchive of Oncology, 2003
BACKGROUND: Breakdown of basement membrane is believed to be an essential step for tumor invasion and metastasis. The interaction between tumor cells and extracellular matrix can also result in induction of basement membrane synthesis by tumor and ...
Fenyvesi Attila
doaj   +1 more source

Basement membranes [PDF]

open access: yesCurrent Biology, 2017
Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues.
Ranjay, Jayadev, David R, Sherwood
openaire   +2 more sources

Basement membrane components [PDF]

open access: yesJournal of Clinical Pathology, 2003
New blood tests in inflammatory bowel disease Idiopathic inflammatory bowel disease (IBD) collectively describes ulcerative colitis (UC) and Crohn’s disease (CD). UC is characterised by inflammation limited to the colonic mucosa and collagen deposition only in the submucosa,1 whereas CD is characterised by transmural, granulomatous inflammation and ...
A C Y, Li, R P H, Thompson
openaire   +2 more sources

Anti-Glomerular Basement Membrane Disease

open access: yesDefinitions, 2020
Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement ...
A. Rees
semanticscholar   +1 more source

Antiglomerular Basement Membrane Disease [PDF]

open access: yesSeminars in Respiratory and Critical Care Medicine, 2014
AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
openaire   +7 more sources

Basement membrane remodelling regulates mouse embryogenesis

open access: yesNature, 2020
Tissue sculpting during development has been attributed mainly to cellular events through processes such as convergent extension or apical constriction1,2.
Christos Kyprianou   +7 more
semanticscholar   +1 more source

Anti-Glomerular Basement Membrane Disease in a 10-year-old Child: A Case Report

open access: yesJournal of Nepal Medical Association, 2023
Anti-glomerular basement membrane disease is an extremely uncommon entity in children. It has an incidence of 0.5 to 1 per million per year in adults and is even more uncommon in children.
Md Firoz Anjum   +4 more
doaj   +1 more source

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