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Long Prehensile Protrusions Can Facilitate Cancer Cell Invasion through the Basement Membrane
A basic process in cancer is the breaching of basement-membrane barriers to permit tissue invasion. Cancer cells can use proteases and physical mechanisms to produce initial holes in basement membranes, but how cells squeeze through this barrier into ...
Shayan S. Nazari +3 more
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Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report
Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
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Mechanisms of Basement Membrane Micro-Perforation during Cancer Cell Invasion into a 3D Collagen Gel
Cancer invasion through basement membranes represents the initial step of tumor dissemination and metastasis. However, little is known about how human cancer cells breach basement membranes.
Shayan S. Nazari +2 more
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The prognostic significance of type IV collagen expression in colorectal carcinomas [PDF]
BACKGROUND: Breakdown of basement membrane is believed to be an essential step for tumor invasion and metastasis. The interaction between tumor cells and extracellular matrix can also result in induction of basement membrane synthesis by tumor and ...
Fenyvesi Attila
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Basement membranes (BMs) are thin, dense sheets of specialized, self-assembled extracellular matrix that surround most animal tissues (Figure 1, top). The emergence of BMs coincided with the origin of multicellularity in animals, suggesting that they were essential for the formation of tissues.
Ranjay, Jayadev, David R, Sherwood
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Basement membrane components [PDF]
New blood tests in inflammatory bowel disease Idiopathic inflammatory bowel disease (IBD) collectively describes ulcerative colitis (UC) and Crohn’s disease (CD). UC is characterised by inflammation limited to the colonic mucosa and collagen deposition only in the submucosa,1 whereas CD is characterised by transmural, granulomatous inflammation and ...
A C Y, Li, R P H, Thompson
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Anti-Glomerular Basement Membrane Disease
Anti-glomerular basement membrane disease (anti-GBM) is a rare but well-characterized cause of glomerulonephritis. It is defined by the presence of autoantibodies directed at specific antigenic targets within the glomerular and/or pulmonary basement ...
A. Rees
semanticscholar +1 more source
Antiglomerular Basement Membrane Disease [PDF]
AbstractAntiglomerular basement membrane (anti-GBM) disease is a rare but life-threatening autoimmune vasculitis that is characterized by the development of pathogenic autoantibodies to type IV collagen antigens expressed in the glomerular and alveolar basement membranes.
McAdoo, SP, Pusey, CD
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Basement membrane remodelling regulates mouse embryogenesis
Tissue sculpting during development has been attributed mainly to cellular events through processes such as convergent extension or apical constriction1,2.
Christos Kyprianou +7 more
semanticscholar +1 more source
Anti-Glomerular Basement Membrane Disease in a 10-year-old Child: A Case Report
Anti-glomerular basement membrane disease is an extremely uncommon entity in children. It has an incidence of 0.5 to 1 per million per year in adults and is even more uncommon in children.
Md Firoz Anjum +4 more
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