Results 41 to 50 of about 2,279,736 (377)
Basement membrane and cell integrity of self-tissues in maintaining Drosophila immunological tolerance. [PDF]
PLoS Genetics, 2014 The mechanism underlying immune system recognition of different types of pathogens has been extensively studied over the past few decades; however, the mechanism by which healthy self-tissue evades an attack by its own immune system is less well ...
Moon Jong Kim, Kwang-Min Choe
doaj +1 more source
The vascular basement membrane in the healthy and pathological brain
Journal of Cerebral Blood Flow and Metabolism, 2017 The vascular basement membrane contributes to the integrity of the blood-brain barrier (BBB), which is formed by brain capillary endothelial cells (BCECs).
M. S. Thomsen, L. J. Routhe, T. Moos
semanticscholar +1 more source
Ultrastructure of neurovascular changes in human diabetic retinopathy [PDF]
, 2018 The previous concept regarding diabetic retinopathy assigned a primary role to hyperglycemia-induced microvascular alterations, while neuronal and glial abnormalities were considered to be secondary to either ischemia or exudation.
Artico, Marco +9 more
core +1 more source
Nature Communications, 2017 At the stage of carcinoma in situ, the basement membrane (BM) segregates tumor cells from the stroma. This barrier must be breached to allow dissemination of the tumor cells to adjacent tissues.
Alexandros Glentis +14 more
semanticscholar +1 more source
Frontiers in Medicine, 2022 Alport syndrome results from a myriad of variants in the COL4A3, COL4A4, or COL4A5 genes that encode type IV (basement membrane) collagens. Unlike type IV collagen α1(IV)2α2(IV)1 heterotrimers, which are ubiquitous in basement membranes, α3/α4/α5 have a ...
Dominic Cosgrove, Jacob Madison
doaj +1 more source
Action of the Metalloproteinases in Gonadal Remodeling during Sex Reversal in the Sequential Hermaphroditism of the Teleostei Fish Synbranchus marmoratus (Synbranchiformes: Synbranchidae) [PDF]
, 2018 Teleostei present great plasticity regarding sex change. During sex reversal, the whole gonadincluding the germinal epithelium undergoes significant changes, remodeling, and neoformation.However, there is no information on the changes that occur within ...
Antoneli, Fernanda +3 more
core +2 more sources
Basement membrane collagens and disease mechanisms
Essays in Biochemistry, 2019 Basement membranes (BMs) are specialised extracellular matrix (ECM) structures and collagens are a key component required for BM function. While collagen IV is the major BM collagen, collagens VI, VII, XV, XVII and XVIII are also present.
Anna Gatseva +3 more
semanticscholar +1 more source
Journal of Medical Case Reports, 2017 Background We report a previously unrecognized and unreported case of a patient with anti-glomerular basement membrane glomerulonephritis following nintedanib, an orally active small molecule tyrosine kinase inhibitor.
Ibrahim Ismail +3 more
doaj +1 more source
Elevated expression of type VII collagen in the skin of patients with systemic sclerosis. Regulation by transforming growth factor-beta. [PDF]
, 1994 A hallmark of systemic sclerosis (SSc) is the development of tissue fibrosis. Excessive production of several connective tissue components normally present in the dermis, including type I, III, V, and VI collagens as well as fibronectin and proteoglycans,
Christiano, Angela M. +5 more
core +3 more sources
Acta Neuropathologica, 2018 Tracers injected into CSF pass into the brain alongside arteries and out again. This has been recently termed the “glymphatic system” that proposes tracers enter the brain along periarterial “spaces” and leave the brain along the walls of veins.
Nazira J. Albargothy +6 more
semanticscholar +1 more source