Results 331 to 340 of about 282,340 (392)

Basic fibroblast growth factor and fibroblast growth factor receptor I are implicated in the growth of human astrocytomas

Journal of Neuro-Oncology, 1994
Malignant astrocytomas are highly invasive, vascular neoplasms that comprise the majority of nervous system tumors in humans. A strong association has previously been made between malignancy in human astrocytic tumors and increased expression of certain fibroblast growth factor (FGF) family members, including basic and acidic FGF.
R S, Morrison, F, Yamaguchi, H, Saya, J M, Bruner, A M, Yahanda, L A, Donehower, M, Berger   +6 more
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Basic fibroblast growth factor and fibroblast growth factor receptor-1 in the human hippocampal formation

Neuroscience, 2005
Basic fibroblast growth factor (bFGF) is an important mitogen and neurotrophic factor that binds and signals through the high-affinity receptor, fibroblast growth factor receptor 1 (FGFR1). However, only a limited amount of information is available concerning the molecular forms and anatomical distribution of fibroblast growth factors (FGFs) in the ...
C S, Weickert, D A, Kittell, R C, Saunders, M M, Herman, R A, Horlick, J E, Kleinman, T M, Hyde   +6 more
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Cardioprotection and Basic Fibroblast Growth Factor

1996
Basic fibroblast growth factor (bFGF, or FGF-2) is a 18–25-kDa basic protein found in variable amounts in all tissues examined (see [1] for a recent review). It is highly conserved between species and belongs to a large family of FGF growth factors (FGF 1—9) with which it shares 40%–50% sequence homology; another widely studied member of this family is
Raymond R. Padua, Lei Liu, Rajat Sethi, Sarah E. Davey-Forgie, Naranjan S. Dhalla, Elissavet Kardami   +5 more
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Expression of basic fibroblast growth factor and fibroblast growth factor receptor in advanced gastric carcinoma

The Journal of Pathology, 1995
AbstractThe expression of basic fibroblast growth factor (bFGF) and fibroblast growth factor receptor (FGFR) mRNA was examined in gastric carcinomas by immunohistochemistry and in situ hybridization, respectively. In the 20 advanced carcinomas examined, bFGF was found in 14 (70·0 per cent) and was confined to the tumour cells, whereas FGFR mRNA was ...
T, Ueki, T, Koji, S, Tamiya, P K, Nakane, M, Tsuneyoshi   +4 more
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Effects of Basic Fibroblast Growth Factor on Rat Vocal Fold Fibroblasts

Annals of Otology, Rhinology & Laryngology, 2010
Objectives The overarching goal of this line of research is to translate basic fibroblast growth factor (bFGF) treatment for vocal fold scarring into practical clinical use. In a previous canine investigation, we demonstrated that bFGF improves phonation threshold pressure, mucosal wave amplitude, and histologic
Atsushi, Suehiro, Shigeru, Hirano, Yo, Kishimoto, Ichiro, Tateya, Bernard, Rousseau, Juichi, Ito   +5 more
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Basic Fibroblast Growth Factor and Angiogenesis

2006
Regenerative medicine using growth factors is an important therapeutic tool in patients with tissue ischemia or defects. Among such therapies, we have mainly addressed the sustained release of basic fibroblast growth factor (bFGF) as a safe and effective treatment.
Akira Marui, Kazuhiko Doi, Keiichi Tambara, Yutaka Sakakibara, Koji Ueyama, Atsushi Iwakura, Masaya Yamamoto, Tadashi Ikeda, Yasuhiko Tabata, Masashi Komeda   +9 more
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BASIC FIBROBLAST GROWTH FACTOR IN HUMAN PITUITARY TUMOURS

Clinical Endocrinology, 1990
SUMMARYImmunoreactive (ir) basic fibroblast growth factor (FGF) has been measured in normal human pituitary glands and in 41 pituitary tumours of various types using a radioimmunoassay. Normal pituitary glands contained ir basic FGF ranging from 29.4 to 355 fmol/mg wet weight whereas 87.5% of pituitary tumours contained amounts of the growth factor ...
J J, Silverlight, R A, Prysor-Jones, J S, Jenkins   +2 more
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Tumor growth regulation by modulation of basic fibroblast growth factor

1992
Fibroblast growth factors (FGF) were initially characterized for their mitogenic properties [1]. Since then, members of this family of growth factors have been shown to be growth stimulatory for a variety of cell types in vitro, including glial cells [2–4].
J L, Gross, W F, Herblin, K, Eidsvoog, R, Horlick, S S, Brem   +4 more
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Basic Fibroblast Growth Factor and Fibrosis in Hodgkin's Disease

Pathology - Research and Practice, 1999
Hodgkin's disease (HD) is characterized by the presence of Hodgkin and Reed-Sternberg (H-RS) cells against a hyperplastic background of reactive cells such as lymphocytes, histiocytes, plasma cells, eosinophils, neutrophils and stromal cells. In addition, the HD nodular sclerosis (NS) subtype shows characteristic fibrous bundles, while the other ...
K, Ohshima, M, Sugihara, J, Suzumiya, S, Haraoka, M, Kanda, K, Shimazaki, K, Katoh, M, Kumagawa, M, Kikuchi   +8 more
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[Basic fibroblast growth factor in leiomyoma].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2005
Fibroblast growth factor (FGF) is a potent stimulator of collagen and glycosaminoglycan biosynthesis and may play an important role in extracellular matrix (ECM) remodelling. Heparin sulphate was shown to be the major proteoglycan molecule in ECM of leiomyoma. It shows ability to bind some growth factors, including FGF.
Małgorzata, Wolańska, Krzysztof, Sobolewski   +1 more
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