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Basic fibroblast growth factor in rat salivary glands
Cell & Tissue Research, 1993We studied the occurrence and localization of basic fibroblast growth factor (bFGF) in rat salivary glands using a specific monoclonal antibody. It was shown that the extract of rat salivary glands has a pronounced stimulatory activity on the growth of bovine capillary endothelial cells, which is blocked by the addition of an antibody against bFGF. The
O, Amano +3 more
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Basic fibroblast growth factor and the complexity of tumour angiogenesis
Expert Opinion on Investigational Drugs, 1998Intrinsic biochemical properties of basic fibroblast growth factor (bFGF) do not adequately explain its potent pro-angiogenic activity. In vivo, bFGF can act in concert with other modulators of angiogenesis, such as vascular endothelial growth factor (VEGF). It is suggested that due to the complexity of angiogenic growth factor networks the process may
J, Rak, R S, Kerbel
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[Astrogliosis and basic fibroblast growth factor].
Zhonghua bing li xue za zhi = Chinese journal of pathology, 1999To study the relationship between reactive astrogliosis and its autocrine bFGF.On the primary astrocyte culture with mechanical scratch, the dynamic expression of bFGF, PCNA, GFAP and GFAP-mRNA were determined by immunocytochemistry and in situ hybridization.Astrocytes at the edge of the injury began to express bFGF 2 hours after scratching and reached
L, Li, Z, Ye, J, Zhu
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Biochemical and Biophysical Research Communications - BBRC, 1992
M. Pepper +3 more
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M. Pepper +3 more
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Basic Fibroblast Growth Factor Gene Expression
Annals of the New York Academy of Sciences, 1991R Z, Florkiewicz +6 more
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Heparin Structure and Interactions with Basic Fibroblast Growth Factor
Science, 1996S. Faham +4 more
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Basic fibroblast growth factor and hematopoiesis.
Leukemia, 1995Basic fibroblast growth factor (bFGF or FGF-2) is an angiogenic and pleiotropic factor involved in the proliferation and differentiation of numerous cell types. It is expressed mostly in tissues of mesoderm and neuroectoderm origin, and plays an important role in the mesoderm induction, together with transforming growth factor-beta (TGF-beta). Although
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